Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM).

26 May 2022

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

In a recent study posted to the medRxiv* pre-print server, researchers assessed whether messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines increase the incidence of glomerulonephritis against the null hypothesis stating any observed temporal association between the two phenomena was purely coincidental.

26 May 2022

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease.

25 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Immune response and the lymphatic system are key to cardiac repair after heart attack

Immune response and the lymphatic system are central to cardiac repair after a heart attack, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg Cardiovascular Research Institute.

25 May 2022

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Patients with non-alcoholic fatty liver disease (NAFLD) are at higher risk of cardiovascular disease, because NAFLD prompts the over-production of a class of proteins that cause inflammation and damage to their blood vessels.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Anosmia in pediatric COVID-19

The current paper, published in The Pediatric Infectious Disease Journal, examines the prevalence of anosmia in children with COVID-19 using a smell awareness survey.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Use of computer-aided technology during colonoscopy increases adenoma detection rate

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27 percent in average-risk patients, according to new data presented today at the Digestive Disease Week Annual Meeting.

24 May 2022

Research provides insight into genetic mechanisms of Wilms tumor

New research from Ann & Robert H. Lurie Children's Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.

24 May 2022

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Across the world, food allergies are on the rise. One of the most important cells in studying this ailment are basophils, which activate inflammation and other responses to allergens such as rashes, and sometimes, anaphylaxis.

23 May 2022

CDC scientists partner with Massachusetts Department of Public Health to investigate a monkeypox case

Scientists at the Centers for Disease Control and Prevention (CDC) are collaborating with the Massachusetts Department of Public Health to investigate a case of monkeypox in a Massachusetts resident who had recently traveled to Canada by private transportation.

23 May 2022

Novel AI algorithm developed for assessing digital pathology data

Digital pathology is an emerging field which deals with mainly microscopy images that are derived from patient biopsies.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Resarchers discuss the ability of shark-derived antibodies to protect against multiple variants of SARS-CoV-2.

23 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients.

19 May 2022

New insights on avian influenza spillover and global spread

When it comes to avian influenza, more commonly known as bird flu, all birds are not created equal.

19 May 2022

Pathology News and Research

Further Reading

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

Researchers identify the genetic causes of three mitochondrial diseases using new approach

Immune response and the lymphatic system are key to cardiac repair after heart attack

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Study unveils the novel driver of cardiomyocyte loss

Anosmia in pediatric COVID-19

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Use of computer-aided technology during colonoscopy increases adenoma detection rate

Research provides insight into genetic mechanisms of Wilms tumor

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

CDC scientists partner with Massachusetts Department of Public Health to investigate a monkeypox case

Novel AI algorithm developed for assessing digital pathology data

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New insights on avian influenza spillover and global spread

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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