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‘Game-changer’ clinical trial launches for Australia’s second-deadliest cancer

A world-first clinical trial launched in Melbourne is being hailed a ‘game-changer’ for its potential to revolutionize the way people with bowel cancer are treated.

29 Apr 2025

Obesity changes how the gut responds to plant compounds, researchers report

Researchers found that the impact of polyphenols rutin and genistein on the human fecal metabolome varies significantly by body mass index (BMI). Lower BMI individuals showed more diverse metabolic responses, revealing how gut health and obesity could shape polyphenol metabolism.

28 Apr 2025

Largest study identifies new genetic targets for osteoarthritis treatment

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

28 Apr 2025

Medicare changes set to lower out-of-pocket costs for cancer medications

Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently.

28 Apr 2025

Distinct subtypes of senescent skin cells identified

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

26 Apr 2025

New Medicare changes ease cost burden for cancer drugs

Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently.

25 Apr 2025

New RNA-based diagnostics to fight against tuberculosis

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent antibiotics can eradicate the Mycobacterium tuberculosis bacteria.

25 Apr 2025

Researchers pioneer method to measure liver tissue stiffness without damage

Researchers in South Korea have developed an organoid disease model and non-destructive stiffness analysis technology for evaluating the efficacy of new drugs for fatty liver disease.

25 Apr 2025

Mouse study confirms early inflammation in hereditary paralysis condition

A joint study conducted by the University of Bonn and the DZNE has confirmed early-stage brain inflammation in mice.

25 Apr 2025

New biomarker offers hope for early Parkinson’s diagnosis

A misfolded protein facilitates reliable diagnosis even in the early stages of Parkinson’s disease in body fluids.

25 Apr 2025

WHO urges renewed global effort to end malaria

On World Malaria Day, the World Health Organization (WHO) is calling for revitalized efforts at all levels, from global policy to community action, to accelerate progress towards malaria elimination.

25 Apr 2025

New era of medicine emerges through structural control of nanotherapeutics

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

25 Apr 2025

Moms in crisis, jobs lost: The human cost of Trump’s addiction funding cuts

When the Trump administration cut more than $11 billion in covid-era funds to states in late March, addiction recovery programs suffered swift losses.

25 Apr 2025

What’s behind Gen Z’s skepticism about Ozempic and Wegovy

A U.S. study of over 500 youth aged 14–24 found high awareness but widespread hesitation about using semaglutide for weight loss. Concerns focused on safety, social stigma, and a preference for lifestyle changes like diet and exercise.

24 Apr 2025

Common diabetes drug can reduce the pain of people with knee osteoarthritis and obesity

A common diabetes drug can reduce the pain of people with knee osteoarthritis and overweight or obesity, possibly delaying the need for knee replacements, Monash University-led research has found.

24 Apr 2025

Global clinical trial tests two anti-inflammatory drugs for long COVID

Spanning four continents and enrolling hundreds of people, a new clinical trial will test the effectiveness of two anti-inflammatory medicines as potential treatments for long COVID, scientists from Western University and the Schmidt Initiative for Long Covid (SILC) announced today.

24 Apr 2025

Neutrophil subpopulations could help predict autoimmune disease relapse

Neutrophils, one of the immune system warriors that were thought to be all the same, turn out to be diverse. Unfortunately, these cells are also active in autoimmune diseases.

24 Apr 2025

New connective tissue cells could open path to pancreatic cancer treatment

Researchers at Umeå University, Sweden, have discovered a previously unknown type of connective tissue cells that surround cancer cells in pancreatic tumors.

24 Apr 2025

Baloxavir marboxil shows promise in reducing household flu spread

One dose of the antiviral baloxavir marboxil lowers the chance of transmitting the influenza virus to family members by about 30%, according to research in the New England Journal of Medicine.

24 Apr 2025

CN Bio and Pharmaron establish long-term strategic partnership to develop OOC technologies on a global R&D platform

CN Bio, a leading provider of Organ-on-a-chip systems and solutions that accelerate drug discovery and development workflows, today announced the establishment of a strategic partnership with Pharmaron, a premier R&D service provider for the life sciences industry.

24 Apr 2025