Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

A predictive model for COVID-19 outcomes

A new technique to solve unbalanced problems for the efficient management of SARS-CoV-2 infected patients according to comorbidities, age, and sex.

9 Mar 2022

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Leptomeningeal disease is a rare complication of several different types of cancer, including melanoma. It occurs when tumor cells migrate to the cerebrospinal fluid and the tissue that surrounds the brain and spinal column known as the meninges.

8 Mar 2022

Women with one ovary less likely to have a successful IVF outcome, study shows

Women who have had one ovary surgically removed (unilateral oophorectomy) are less likely to become pregnant after in vitro fertilization and give birth to fewer babies than women with both ovaries.

8 Mar 2022

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Helping to advance Alzheimer’s disease (AD) research, scientists from The Feinstein Institutes for Medical Research have published two studies supporting the connection of tau – a protein in the brain that forms neurofibrillary tangles that are a hallmark of AD and have been linked to chronic traumatic encephalopathy (CTE) from head trauma – with psychosis in AD.

8 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Researchers demonstrated the relative pathogenicity of SARS-CoV-2 Omicron and Delta variants of concern in Syrian hamsters.

7 Mar 2022

Canopy Biosciences launches next-generation ChipCytometry™ instrument for spatial biology with sub-cellular resolution

Canopy Biosciences, a Bruker Company, today announced the commercial launch of the CellScape™ system, the next generation in ChipCytometry™ instrumentation, advancing the cutting-edge for quantitative in situ spatial phenotyping.

From Bruker Nano Surfaces and Metrology 7 Mar 2022

New DNA test can quickly and accurately identify a range of hard-to-diagnose genetic diseases

A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.

4 Mar 2022

Study identifies unique features of MIS-C and how the syndrome gets started in children

A new study by physicians at Columbia University Vagelos College of Physicians and Surgeons has identified unique features of MIS-C, a rare but potentially deadly complication of COVID in children, that suggest how the syndrome gets started.

4 Mar 2022

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

A high-fat diet is not enough to cause short-term fatty liver disease. However, if this diet is combined with the intake of beverages sweetened with liquid fructose, the accumulation of fats in the liver accelerates and hypertriglyceridemia —a cardiovascular risk factor— can appear.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Alzheimer's disease usually is diagnosed based on symptoms, such as when a person shows signs of memory loss and difficulty thinking.

2 Mar 2022

Study unravels why women are more susceptible to Alzheimer’s disease

Epidemiological studies have shown that women are twice as likely as men to develop Alzheimer's disease (AD), but the cause of this phenomenon has been unclear.

2 Mar 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Peer-led online communities effective in increasing HIV self-testing among MSM of color

A new University of California, Irvine-led study, called the HOPE (Harnessing Online Peer Education) HIV study, revealed that using peer-led online communities was successful in increasing HIV self-testing and reducing alcohol consumption among Latinx and African American MSM (men who have sex with men).

28 Feb 2022

Studying coagulopathy in COVID-19

A new study published in the journal Diagnostics provided an overview of ROTEM with a particular focus on interpreting the symmetrical clot formation curve. Researchers also introduced new parameters that could aid in distinguishing between COVID-19 patients and outcomes.

28 Feb 2022

Pathology News and Research

Further Reading

A predictive model for COVID-19 outcomes

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Women with one ovary less likely to have a successful IVF outcome, study shows

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

How have human organoids been used in research to study SARS-CoV-2?

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Canopy Biosciences launches next-generation ChipCytometry™ instrument for spatial biology with sub-cellular resolution

New DNA test can quickly and accurately identify a range of hard-to-diagnose genetic diseases

Study identifies unique features of MIS-C and how the syndrome gets started in children

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

Researchers identify genetic link between lymphatic disorder and stillbirth

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Study unravels why women are more susceptible to Alzheimer’s disease

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Peer-led online communities effective in increasing HIV self-testing among MSM of color

Studying coagulopathy in COVID-19

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

New analysis on intersectionality in cancer care

Genetic analysis reveals eosinophilic colitis as a unique disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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