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New research sheds light on CDK7's role in cancer cell proliferation

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge.

25 Mar 2025

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

25 Mar 2025

New open-source tool identifies aging cells to help fight chronic diseases

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer's disease and other chronic diseases.

25 Mar 2025

New insights into therapy resistance in breast cancer

A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer."

25 Mar 2025

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical forces in tissues including stress, strain, and stiffness.

25 Mar 2025

New evidence suggests HPV could increase risk of coronary artery disease

In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

Mapping the brain network behind generalized epilepsy

Frederic L.W.V.J. Schaper, MD, PhD, director of Epilepsy Network Mapping at the Center for Brain Circuit Therapeutics at Brigham and Women's Hospital and an instructor of neurology at Harvard Medical School, is the senior author of a paper published in Nature Communications, "A generalized epilepsy network derived from brain abnormalities and deep brain stimulation."

25 Mar 2025

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Research identifies pressure-sensing protein behind gut motility

After every meal, the intestines perform an action called peristalsis - moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle.

25 Mar 2025

ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025

ELRIG, a not-for-profit, volunteer-led organization for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D site in Gothenburg, Sweden from 14-15 May. Prof Rory Johnson, Associate Professor, University College Dublin, and Dr Shalini Andersson, Vice President Nucleic Acid Therapeutics, AstraZeneca will lead this year's event focused on 'drugging the undruggable'.

25 Mar 2025

US Patent Office grants Closed Loop Medicine key patents for cardiometabolic capabilities in GLP-1 and Direct Oral Anti-Coagulants (DOAC) therapies

Closed Loop Medicine Ltd., a leader in AI-enabled precision medicines, today announced the expansion of its US patent portfolio. Strengthening its cardiometabolic treatment portfolio, the Company now has patents covering advancements in GLP-1 therapies for obesity and diabetes, and direct oral anticoagulants (DOACs) for cardiovascular health.

25 Mar 2025

New brain circuit involved in motion sickness could help improve metabolic health

Motion sickness is a very common condition that affects about 1 in 3 people, but the brain circuits involved are largely unknown. In the current study published in Nature Metabolism, researchers at Baylor College of Medicine, the University of Texas Health Science Center at Houston and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital describe a new brain circuit involved in motion sickness that also contributes to regulating body temperature and metabolic balance.

24 Mar 2025

Ancient appetite-control molecule found in starfish and humans

A team of biologists at Queen Mary University of London has discovered that a neurohormone controlling appetite in humans has an ancient evolutionary origin, dating back over half a billion years.

24 Mar 2025

Novel long-acting contraceptive implant can be delivered through tiny needles

Mass General Brigham and MIT investigators have developed a long-acting contraceptive implant that can be delivered through tiny needles to minimize patient discomfort and increase the likelihood of medication use.

24 Mar 2025

New MIT method promises less painful drug injections with tiny crystals

MIT engineers have devised a new way to deliver certain drugs in higher doses with less pain, by injecting them as a suspension of tiny crystals.

24 Mar 2025

Combination therapy could prevent thousands of cardiovascular deaths

The largest analysis to examine the best way to lower levels of 'bad' cholesterol in patients with blocked arteries shows that they should immediately be given a combination of a statin and another drug called ezetimibe, rather than statins alone.

24 Mar 2025

The Colorado psychedelic mushroom experiment has arrived

Colorado regulators are issuing licenses for providing psychedelic mushrooms and are planning to authorize the state's first "healing centers," where the mushrooms can be ingested under supervision, in late spring or early summer.

24 Mar 2025

New light-driven process could accelerate the discovery of new drugs

Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact with the body.

22 Mar 2025

Healthcare groups urge FDA to act on compounding regulations after GLP-1 medicine shortages

Today, the Obesity Action Coalition (OAC) and The Obesity Society (TOS) sent a letter to the U.S. Food & Drug Administration (FDA), along with more than 20 leading organizations and providers across the healthcare continuum, urging the agency to enforce federal regulations around compounding following the recent resolution of GLP-1 medicine shortages.

22 Mar 2025

Concierge approach enables more people to receive kidney transplants and erases disparities

Patients hoping for a kidney transplant must first undergo a battery of medical tests to determine whether they are suitable candidates for the procedure and healthy enough to take post-transplant immunosuppressant drugs to prevent organ rejection.

22 Mar 2025

Drugs News and Research

New research sheds light on CDK7's role in cancer cell proliferation

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

New open-source tool identifies aging cells to help fight chronic diseases

New insights into therapy resistance in breast cancer

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

New evidence suggests HPV could increase risk of coronary artery disease

Mapping the brain network behind generalized epilepsy

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Research identifies pressure-sensing protein behind gut motility

ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025

US Patent Office grants Closed Loop Medicine key patents for cardiometabolic capabilities in GLP-1 and Direct Oral Anti-Coagulants (DOAC) therapies

New brain circuit involved in motion sickness could help improve metabolic health

Ancient appetite-control molecule found in starfish and humans

Novel long-acting contraceptive implant can be delivered through tiny needles

New MIT method promises less painful drug injections with tiny crystals

Combination therapy could prevent thousands of cardiovascular deaths

The Colorado psychedelic mushroom experiment has arrived

New light-driven process could accelerate the discovery of new drugs

Healthcare groups urge FDA to act on compounding regulations after GLP-1 medicine shortages

Concierge approach enables more people to receive kidney transplants and erases disparities

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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