Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Research explores sex differences in placental defenses against SARS-CoV-2 infection

A plethora of earlier studies has reported on the differences between the sexes in susceptibility to the currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as its severity. A new preprint research paper posted to the bioRxiv* server extends this to the placenta in pregnancy.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

Diet and lifestyle may play a significant role in Alzheimer's disease

For years, research to pin down the underlying cause of Alzheimer's Disease has been focused on plaque found to be building up in the brain in AD patients.

2 Apr 2021

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses--like influenza--that might be mistaken for the coronavirus.

31 Mar 2021

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Introducing a neuro regenerative gene into mice with spinal cord injury improves motor function

Nagoya University researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration.

31 Mar 2021

SARS-CoV-2 inhibits the cellular response to interferon

Researchers have explored the effect of SARS-CoV-2 infection on the function of RIG-I and MDA5, and ultimately on interferon production.

31 Mar 2021

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.

31 Mar 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Vaccine-induced 2C08 antibody protects against SARS-CoV-2 variants

A new preprint study posted to the bioRxiv* server led by Ali H. Ellebedy from the Washington University School of Medicine found that the monoclonal antibody 2C08 produced by the Pfizer vaccine could help neutralize COVID-19 variants.

29 Mar 2021

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

Apes mount a much stronger early immune response compared to African and Asian monkeys

A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions.

29 Mar 2021

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

A review of more than 20 studies by researchers at Arizona State University and the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that nonalcoholic fatty-liver disease (NAFLD) is a growing dietary problem for children across the globe.

29 Mar 2021

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.

29 Mar 2021

New modeling approach to better understand how tumors become aggressive

Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood.

29 Mar 2021

DNMT3a plays a key role in regulating HSC responses to infections

Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.

26 Mar 2021

Study may provide an explanation for dawn phenomenon in patients with type 2 diabetes

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the morning, observed in many patients with type 2 diabetes.

25 Mar 2021

Study identifies NCOA3 as a novel therapeutic target for melanoma

For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention of the DNA damage response.

25 Mar 2021

Gene Expression News and Research

Further Reading

Research explores sex differences in placental defenses against SARS-CoV-2 infection

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

New RNA-sequencing method can help detect numerous modified small RNAs

Diet and lifestyle may play a significant role in Alzheimer's disease

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Introducing a neuro regenerative gene into mice with spinal cord injury improves motor function

SARS-CoV-2 inhibits the cellular response to interferon

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Vaccine-induced 2C08 antibody protects against SARS-CoV-2 variants

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Apes mount a much stronger early immune response compared to African and Asian monkeys

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

New modeling approach to better understand how tumors become aggressive

DNMT3a plays a key role in regulating HSC responses to infections

Study may provide an explanation for dawn phenomenon in patients with type 2 diabetes

Study identifies NCOA3 as a novel therapeutic target for melanoma

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