Therapeutics News and Research

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Break Through Cancer funds AML research at MD Anderson

The University of Texas MD Anderson Cancer Center was awarded more than $5.7 million in grants from Break Through Cancer to support collaborative research teams working to discover novel molecular targets to eradicate minimal residual disease in acute myeloid leukemia (AML) and to treat clonal hematopoiesis, a precursor to AML.

16 May 2023

Next-Generation EV Separation: Izon Science and Agarose Bead Technologies Collaborate to Enhance Clinical Applications for Extracellular Vesicles

A collaborative agreement between Izon Science and Agarose Bead Technologies (ABT) offers exceptional opportunities to develop solutions that aid in advancing EV research into clinical settings.

From Agarose Bead Technologies 16 May 2023

PhenomeX Launches Beacon Select™ Optofluidic System with Opto® B Discovery Workflows

Affordable two-chip Beacon Select system to broaden customer access to innovative high throughput, function-first antibody discovery capabilities.

From Bruker Cellular Analysis 16 May 2023

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Through a recent platform demonstration project, LabGenius’ machine learning-driven lead optimisation capability delivered dozens of novel T-cell engagers with best-in-class killing selectivity.

From LabGenius 16 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

Nominations open now for BIAL Award in Biomedicine

The third edition of the BIAL Foundation's international award, the BIAL Award in Biomedicine, is now underway, with nominations open until 30 June.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Researchers develop a computational approach to predict diabetic kidney disease

Researchers from Sanford Burnham Prebys and the Chinese University of Hong Kong have developed a computational approach to predict whether a person with type 2 diabetes will develop kidney disease, a frequent and dangerous complication of diabetes.

15 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Cytiva and Pall Life Sciences complete integration to create a global innovation and solutions leader in biotechnology

Cytiva and the life sciences business of Pall Corporation have completed their integration and are now united as one business under the Cytiva brand.

12 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

New SNAP approach to customizing T cell-based immunotherapies

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases.

9 May 2023

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

New research from Boston Medical Center found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis.

9 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

Study may provide new avenues for addressing somatosensory symptoms of long COVID

COVID-19, the disease resulting from SARS-CoV-2 infection, is associated with highly variable clinical outcomes that range from asymptomatic disease to death.

9 May 2023

Researchers call for urgent measures to prevent hospitals from becoming infected with CRAB bacteria

Carbapenem-resistant Acinetobacter baumannii (CRAB) was brought into the ICU, in Hangzhou, on multiple occasions as patients were admitted, creating a large 'reservoir' of the bacteria which contaminated beds and equipment.

9 May 2023

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

9 May 2023

AI-based population screening could expedite the diagnosis of pancreatic cancer

An artificial intelligence tool has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis using solely the patients' medical records, according to new research led by investigators at Harvard Medical School and the University of Copenhagen, in collaboration with VA Boston Healthcare System, Dana-Farber Cancer Institute, and the Harvard T.H. Chan School of Public Health.

8 May 2023

Cancer-fighting immune cells can fuel their ability to attack tumors

When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.

8 May 2023

Therapeutics News and Research

Break Through Cancer funds AML research at MD Anderson

Next-Generation EV Separation: Izon Science and Agarose Bead Technologies Collaborate to Enhance Clinical Applications for Extracellular Vesicles

PhenomeX Launches Beacon Select™ Optofluidic System with Opto® B Discovery Workflows

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Nominations open now for BIAL Award in Biomedicine

Newly identified genetic variant provides protection from Alzheimer's disease

Researchers develop a computational approach to predict diabetic kidney disease

Using an intracellular toolkit to map organelle bio-geography in stem cells

Cytiva and Pall Life Sciences complete integration to create a global innovation and solutions leader in biotechnology

Research sheds light on the early cellular events that give rise to pancreatic cancer

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

New SNAP approach to customizing T cell-based immunotherapies

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

Boosting gut health with short-chain fatty acids

Study may provide new avenues for addressing somatosensory symptoms of long COVID

Researchers call for urgent measures to prevent hospitals from becoming infected with CRAB bacteria

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

AI-based population screening could expedite the diagnosis of pancreatic cancer

Cancer-fighting immune cells can fuel their ability to attack tumors

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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