High throughput screening News and Research

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High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

Russian researchers come up with faster method to discover antibiotics

Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties.

26 Sep 2019

Bath researchers identify promising prostate cancer drug candidates

Cancer researchers from the University of Bath have identified some promising drug candidates by using high-throughput screening methods to test tens of thousands of molecules.

24 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

Diet can alter efficacy of type-2 diabetes drug via its action on gut bacteria, study shows

Research published in Cell on 29th August by the groups of Filipe Cabreiro from the MRC London Institute of Medical Sciences and Imperial College and Christoph Kaleta from Kiel University in Germany has demonstrated that diet can alter the effectiveness of a type-2 diabetes drug via its action on gut bacteria.

30 Aug 2019

Potential drug could revolutionize the treatment of neurological conditions

The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons.

28 Aug 2019

Innovative single-chip platform speeds up drug development process

Scientists at the Karlsruhe Institute of Technology (KIT) have come up with a miniaturized and accelerated system of new drug development on just one chip, promising to make the process faster and cheaper than ever before. The report was published in the journal Nature Communications on June 28, 2019.

16 Jul 2019

New chemBIOS platform for drug development

In spite of increasing demand, the number of newly developed drugs decreased continuously in the past decades.

15 Jul 2019

Researchers open the door to a new era of medicinal chemistry

Progress in the pharmaceutical industry depends largely on the achievements and advances in medicinal chemistry.

14 Jul 2019

IDT and 3CR team up to widen access to custom solutions for genotyping screening

In the latest collaboration in a series to advocate for genomics research, Integrated DNA Technologies is teaming up with 3CR Bioscience to widen access to quality custom solutions for genotyping screening.

From Integrated DNA Technologies 3 Jul 2019

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019

Ziath announces opening of direct operations in the U.S.

Instrumentation control and information management product specialists - Ziath has announced the opening of direct operations in the US with the appointment of a general manager.

From Ziath Ltd 22 May 2019

Scientists develop new test to examine a drug's embryotoxicity in cell cultures

Medications have to be safe for mothers-to-be and for their unborn children. Before the authorities will approve a new drug, it must be tested in animal trials on pregnant rodents and, as a rule, pregnant rabbits.

14 May 2019

Porvair Sciences' ultra-flat Krystal glass bottom microplates for imaging applications

The family of ultra-flat Krystal glass bottom microplates from Porvair Sciences provide unmatched performance for high-throughput screening and tissue culture applications.

From Porvair Sciences Limited 26 Apr 2019

Novel system enables researchers to study bacteria within mini-tissues in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology.

19 Apr 2019

Scientists develop new approach to unravel toxic effects of multiple stressors

Genomic markers are the key in a new approach for assessing the toxic effects arising from exposure to multiple stressors.

11 Apr 2019

AACR Annual Meeting 2019 Highlighted Latest Advances in Cancer Research

On Friday, March 29 to Wednesday, April 3, the Georgia World Congress Center in Atlanta, Georgia, hosted the AACR Annual Meeting 2019.

From 10x Genomics, Inc. 4 Apr 2019

Piece of puzzle unlocked in what drives alcohol addiction

Researchers at the Scripps Research Institute have made an important discovery that may help to explain the neural mechanism that drives alcohol consumption in cases of addiction.

19 Mar 2019

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats--with the flip of a switch.

19 Mar 2019

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Researchers at the George Washington University Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.

15 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019