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IU researchers aim to develop a new therapy for glaucoma

Researchers at Indiana University School of Medicine are using a novel approach to hopefully develop a new therapy for glaucoma, a complex disease that eventually leads to blindness, thanks to a new five-year, $2 million R01 grant from the National Eye Institute.

8 Jan 2024

Bariatric surgery may mitigate the natural history of cognitive decline in people with obesity

Within the next 10 years, it's projected that up to 50% of United States adults will be affected by obesity, which is associated with cognitive impairment and dementia.

8 Jan 2024

Rising out-of-pocket costs for PrEP threaten key strategy in ending the HIV epidemic

Increasing patients' out of pocket costs for HIV pre-exposure prophylaxis (PrEP), medications, which have been shown to dramatically reduce the risk of HIV infection, could lead to a significant reduction in PrEP use and a rise in HIV infection rates, according to a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania and Johns Hopkins Bloomberg School of Public Health.

8 Jan 2024

States begin tapping Medicaid dollars to combat gun violence

To tackle America's gun problem, a growing number of states are using Medicaid dollars to pay for community-based programs intended to stop shootings.

5 Jan 2024

Bipolar disorder cuts lives short more than smoking

Having bipolar disorder – a serious mental illness that can cause both manic and depressed moods – can make life more challenging.

4 Jan 2024

Novel population health tool for predicting ICU survivorship and mortality in older adults

A significant obstacle to improving care and outcomes for intensive care unit (ICU) patients is the unexpected nature of becoming seriously ill.

4 Jan 2024

Pre-pregnancy stress raises blood sugar during pregnancy, study finds

A new Journal of the Endocrine Society study among women attending a fertility center found that those with more stress before pregnancy had higher blood sugar levels during pregnancy, which is a sign of weaker cardiovascular health.

4 Jan 2024

Maternal stress during preconception associated with higher blood glucose levels, study finds

Stress during pregnancy is known to influence health outcomes, but a new study from Mass General Brigham researchers suggests that stress levels before pregnancy are also important to evaluate.

4 Jan 2024

Research identifies genetic connection between anorexia and morning chronotype

New research indicates that the eating disorder anorexia nervosa is associated with being an early riser, unlike many other disorders that tend to be evening-based such as depression, binge eating disorder and schizophrenia.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Doctors are as vulnerable to addiction as anyone. California grapples with a response.

Ariella Morrow, an internal medicine doctor, gradually slid from healthy self-esteem and professional success into the depths of depression.

4 Jan 2024

New approach leverages macrophages to treat traumatic brain injury

Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs.

3 Jan 2024

Missing proteins explain century-old mystery of scalp skin absence in children

Children with the condition aplasia cutis congenita (ACC) are born with the absence of skin along the midline of the scalp.

3 Jan 2024

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Researchers from Rutgers and other institutions have uncovered significant variations in how inflammatory bowel disease (IBD) affects people of different races, sexes and places of birth.

3 Jan 2024

New study demystifies clinicians' decision-making process for drug-drug interactions

Drug-drug interactions causing adverse effects are common and can cause significant patient harm and even death.

3 Jan 2024

New brain imaging technique sheds light on invisible mTBIs

Researchers have created a new brain imaging method that allows mild traumatic brain injuries (mTBIs) to be diagnosed, even when existing imaging techniques like magnetic resonance imaging (MRI) don't show any structural abnormalities.

3 Jan 2024

MGH study identifies key proteins linked to pregnancy hypertension disorders

Preeclampsia and other hypertensive disorders of pregnancy-;which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy-;carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste.

2 Jan 2024

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte-stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.

2 Jan 2024

Medical School News and Research

IU researchers aim to develop a new therapy for glaucoma

Bariatric surgery may mitigate the natural history of cognitive decline in people with obesity

Rising out-of-pocket costs for PrEP threaten key strategy in ending the HIV epidemic

States begin tapping Medicaid dollars to combat gun violence

Bipolar disorder cuts lives short more than smoking

Novel population health tool for predicting ICU survivorship and mortality in older adults

Pre-pregnancy stress raises blood sugar during pregnancy, study finds

Maternal stress during preconception associated with higher blood glucose levels, study finds

Research identifies genetic connection between anorexia and morning chronotype

Unmasking the persistent threats of long-COVID's pulmonary sequelae

Doctors are as vulnerable to addiction as anyone. California grapples with a response.

New approach leverages macrophages to treat traumatic brain injury

Missing proteins explain century-old mystery of scalp skin absence in children

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

New study demystifies clinicians' decision-making process for drug-drug interactions

New brain imaging technique sheds light on invisible mTBIs

MGH study identifies key proteins linked to pregnancy hypertension disorders

Existing beta blocker investigated as novel sickle cell therapy

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

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