immunity News and Research

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Intense light therapy reduces hypoxia-induced heart damage in mice

Right ventricular (RV) remodeling and dysfunction are serious cardiovascular consequences due to prolonged hypoxic exposure, commonly seen in conditions such as chronic lung disease and high-altitude environments.

10 Apr 2026

Social closeness drives the exchange of gut bacteria

Living with friends may quietly be altering your gut bacteria - according to a new study from the University of East Anglia.

10 Apr 2026

Vibrio cholerae acquires antiviral defenses through horizontal gene transfer

Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with antiviral immune systems.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

New monoclonal antibody shows promise for preventing Lyme disease

A Phase I clinical trial of a human monoclonal antibody discovered and developed at UMass Chan Medical School for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data presented by Mark Klempner, MD, at the World Vaccine Congress 2026 in Washington D.C.

8 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

High-dose flu vaccine reduces Alzheimer’s risk in older adults

A study reveals high-dose influenza vaccines could modestly reduce Alzheimer's risk in older adults, especially women, offering new insights into prevention.

8 Apr 2026

Declining booster uptake after vaccine schedule change in England

The change to a 1+1 pneumococcal vaccine schedule in England highlights rising inequalities in booster uptake, threatening protection for at-risk children.

7 Apr 2026

New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

Novel mucosal vaccine offers broad protection against diverse influenza viruses

A novel vaccine platform has been developed to induce broad, protective immunity against numerous influenza virus infections, showing promise as an effective mucosal vaccine strategy, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

3 Apr 2026

Machine learning uncovers thousands of unknown bacterial immune defense systems

Bacterial immune systems protect against viral invaders called phages by precisely targeting specific phage genetic sequences.

2 Apr 2026

Boosting mitochondrial function in dendritic cells can improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy. Dendritic cells activate the cytotoxic immune cells that destroy cancer.

2 Apr 2026

High-dose flu shots inked to lower Alzheimer's dementia risk in older adults

A large US claims-based study found that adults aged 65 and older who received a high-dose flu vaccine had a lower observed risk of Alzheimer dementia than those who received a standard-dose vaccine, with the association lasting up to 25 months in per-protocol analyses and 28 months in intention-to-treat analyses. The signal appeared stronger and more sustained in women, though the authors stress that the findings are observational and need confirmation in longer prospective studies.

2 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

Gut microbiome changes improve memory in early cognitive decline

Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.

1 Apr 2026

Aging reshapes breast tissue creating environment favorable for cancer

Scientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age – including dramatic changes during menopause.

31 Mar 2026

Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics.

31 Mar 2026

How the nutrient cysteine controls cancer-fighting power of T cells

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

31 Mar 2026

New T cell mechanism could lead to longer-lasting vaccines

Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer lasting vaccines for respiratory viruses like influenza and the coronavirus that causes COVID-19.

31 Mar 2026

Gut-derived metabolites regulate immune cells in complex ways

Published on March 23, 2026, in Volume 2, article number 18 of the journal Immunity & Inflammation, the review begins by systematically outlining the sources and synthetic pathways of immune-relevant microbial metabolites, including bile acids, short-chain fatty acids, amino acid derivatives, vitamins, trimethylamine/trimethylamine N-oxide, and odd-chain fatty acids.

31 Mar 2026