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New review explains how circular RNAs could unlock fat browning therapies

A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.

26 Feb 2026

New Mandarin cognitive tests improve dementia diagnosis for Chinese older adults

Asian Americans are the fastest-growing group of older adults in the U.S., but they often face language and cultural barriers when seeking care for dementia-related symptoms.

26 Feb 2026

Unexpected behavior observed during interactions between immune cells and dying cells

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm by a robust nuclear envelope.

25 Feb 2026

Measuring AI acceptance among Japanese medical students and rresident physicians

Artificial intelligence (AI) is rapidly transforming healthcare and medical education. From enhancing diagnostic accuracy and clinical decision-making to enabling virtual simulations and personalized learning, AI technologies are becoming embedded in the daily practice of clinicians and trainees.

24 Feb 2026

Automated platform finds unexpected enhancers for mRNA therapeutics

Integrating AI with advanced robotics to create self-driving labs (SDL) is a promising approach to tackling molecular discovery.

24 Feb 2026

ChatGPT Health fails critical emergency and suicide safety tests

ChatGPT Health, a widely used consumer artificial intelligence (AI) tool that provides health guidance directly to the public-including advice about how urgently to seek medical care-may fail to direct users appropriately to emergency care in a significant number of serious cases, according to researchers at the Icahn School of Medicine at Mount Sinai.

24 Feb 2026

Throwing cancer-driving proteins in the cellular trash

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them - throw them in the cellular trash.

24 Feb 2026

Syndex Bio unveils mcPCR technology at AGBT 2026 following $15.5 M seed financing

Syndex Bio, a biotechnology company advancing next‑generation molecular diagnostics, today announced the introduction of its proprietary mcPCR™ (methyl‑copying PCR) platform at the Advances in Genome Biology and Technology (AGBT) conference in Orlando, Florida.

23 Feb 2026

Brain injury protein in the blood could help estimate biological age in animals

The protein "neurofilament light chain" (NfL) – studied in humans in the context of neurodegenerative diseases and aging – is also detectable in the blood of numerous animals, and NfL levels increase with age in mice, cats, dogs, and horses.

20 Feb 2026

Remote-controlled CAR T cells offer safer cancer therapy

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers.

19 Feb 2026

Study reveals distinct brain roles for MNK1 and MNK2 enzymes

Researchers at the Max Delbrück Center show that two related enzymes, MNK1 and MNK2, act on the brain to regulate different behaviors.

19 Feb 2026

New technology maps protein production across individual brain cells

The brain's ability to carry out everything from forming memories to coordinating movement depends on its cells producing the right proteins at the right time.

18 Feb 2026

Bilingual mothers stay neurally synchronized with children across languages

Interbrain synchrony is the simultaneous activity of neural networks across the brains of people who are socially interacting –- for example talking, learning, singing, or working together.

18 Feb 2026

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, inflammatory, mitochondrial, and proteostasis pathways. Evidence from mechanistic, preclinical, and early clinical studies suggests potential neuroprotective effects, but definitive disease-modifying benefit remains unproven.

17 Feb 2026

JAX-NYSCF collaborates with GSK to advance human cellular models of neurodegenerative disease

The Jackson Laboratory–New York Stem Cell Foundation Collaborative (JAX-NYSCF) today announced a five-year strategic research collaboration with GSK focused on advancing human cellular models of neurodegenerative disease, including Alzheimer's disease.

17 Feb 2026

A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division.

17 Feb 2026

Study explores how reversible RNA editing could transform future cardiovascular medicine

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

15 Feb 2026

Study reveals insights into how cells coordinate gene compensation response

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms.

12 Feb 2026

Study highlights key role of non-contractile cardiac cells in persistent atrial fibrillation

Atrial fibrillation (AF), the most common chronic cardiac arrhythmia in clinical practice, is very challenging to treat once it becomes persistent, after which spontaneous return to normal rhythm becomes highly unlikely.

12 Feb 2026

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Researchers engineered CD4+ chimeric antigen receptor T cells targeting fibrillar amyloid beta and tested them in a mouse Alzheimer model. The preclinical study showed reduced amyloid pathology and altered neuroimmune responses, supporting CAR-T immunotherapy as a potential future Alzheimer strategy.

11 Feb 2026

Translation News and Research

New review explains how circular RNAs could unlock fat browning therapies

New Mandarin cognitive tests improve dementia diagnosis for Chinese older adults

Unexpected behavior observed during interactions between immune cells and dying cells

Measuring AI acceptance among Japanese medical students and rresident physicians

Automated platform finds unexpected enhancers for mRNA therapeutics

ChatGPT Health fails critical emergency and suicide safety tests

Throwing cancer-driving proteins in the cellular trash

Syndex Bio unveils mcPCR technology at AGBT 2026 following $15.5 M seed financing

Brain injury protein in the blood could help estimate biological age in animals

Remote-controlled CAR T cells offer safer cancer therapy

Study reveals distinct brain roles for MNK1 and MNK2 enzymes

New technology maps protein production across individual brain cells

Bilingual mothers stay neurally synchronized with children across languages

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

JAX-NYSCF collaborates with GSK to advance human cellular models of neurodegenerative disease

A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer

Study explores how reversible RNA editing could transform future cardiovascular medicine

Study reveals insights into how cells coordinate gene compensation response

Study highlights key role of non-contractile cardiac cells in persistent atrial fibrillation

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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