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Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed an innovative strategy to construct a series of biodegradable cesium nanosalts.

4 Nov 2025

Study highlights bioengineered models as key to early cancer detection

Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it's more treatable and survival rates are highest.

3 Nov 2025

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Novel approaches to understanding EETs and cardiovascular disease

Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central mediators of inflammation, fever, and pain.

31 Oct 2025

AI indelibly transforms solid tumor drug development

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development.

29 Oct 2025

Broad-spectrum antivenom could revolutionize treatment of venomous snakebites in Africa

DTU researchers are behind a potentially groundbreaking antivenom that could revolutionize the treatment of venomous snakebites in Africa.

29 Oct 2025

First self-powered spinal implant can transmit real-time data from inside the body

A collaboration between civil engineering and neurosurgery at the University of Pittsburgh could change how spinal fusion surgery is performed and monitored. Associate Professors Amir Alavi, Nitin Agarwal, and D. Kojo Hamilton have received a $352,213 National Institutes of Health (NIH) R21 grant to develop the first self-powered spinal implant capable of transmitting real-time data from inside the body.

28 Oct 2025

GemPharmatech collaborates with MSK Cancer Center to accelerate discovery of therapeutic antibodies

GemPharmatech, a global leader in preclinical research solutions and genetically-engineered mouse models, today announced a collaboration with Memorial Sloan Kettering Cancer Center (MSK) to accelerate the discovery of new therapeutic antibodies.

23 Oct 2025

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University of Technology, University of Queensland, and Nanjing Stomatological Hospital has introduced groundbreaking three-dimensional (3D) dynamic cell co-culture models to simulate metabolic dysfunction-associated steatotic liver disease (MASLD) progression stages.

22 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

Gut bacteria found to make serotonin and boost intestinal motility

Researchers have identified Limosilactobacillus mucosae and Ligilactobacillus ruminis as human gut bacteria capable of producing serotonin by decarboxylating 5-hydroxytryptophan (5-HTP). Their activity enhances intestinal motility and enteric nerve density, linking microbial serotonin synthesis to gut function and potential IBS mechanisms.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

Ingestible bioprinter offers minimally invasive tissue repair

Soft tissue injuries of the gastrointestinal tract, like ulcers or hemorrhages, can currently be treated only with some form of surgery, which is invasive and may not result in permanent repair.

16 Oct 2025

Ganoderma lucidum protects against liver damage from high-fat diets

A long-term high-fat diet (HFD) exerts lipotoxic effects on multiple organs, particularly the liver, leading to metabolic diseases.

16 Oct 2025

New insights into how bacteria can drive treatment resistance in oral and colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer.

16 Oct 2025

UC Irvine develops human-like colon model for precision medicine

Researchers at the University of California, Irvine have developed a 3D human colon model integrated with bioelectronics to aid in colorectal cancer research and drug discovery.

15 Oct 2025

Does eating watermelon lower blood pressure?

Researchers reviewed the role of watermelon as a natural source of L-citrulline and its potential to improve cardiovascular health by enhancing nitric oxide production. While promising effects on blood pressure and arterial stiffness were seen in at-risk groups, long-term and dose-specific studies are still needed to confirm clinical benefits.

15 Oct 2025

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

15 Oct 2025

CU Boulder researchers advance miniature laser technology for biomedical imaging

Darwin Quiroz is exploring new frontiers in miniature lasers with major biomedical applications.

14 Oct 2025

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

in vivo News and Research

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Study highlights bioengineered models as key to early cancer detection

Pioneering technology enables scalable production of human kidney organoids

Novel approaches to understanding EETs and cardiovascular disease

AI indelibly transforms solid tumor drug development

Broad-spectrum antivenom could revolutionize treatment of venomous snakebites in Africa

First self-powered spinal implant can transmit real-time data from inside the body

GemPharmatech collaborates with MSK Cancer Center to accelerate discovery of therapeutic antibodies

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

New drug combination shows promise in treating colorectal cancer

Gut bacteria found to make serotonin and boost intestinal motility

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Ingestible bioprinter offers minimally invasive tissue repair

Ganoderma lucidum protects against liver damage from high-fat diets

New insights into how bacteria can drive treatment resistance in oral and colorectal cancer

UC Irvine develops human-like colon model for precision medicine

Does eating watermelon lower blood pressure?

What happens when microplastics reach the testes? Study shows autophagy and cell loss

CU Boulder researchers advance miniature laser technology for biomedical imaging

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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