Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Return of mice to home cage evokes significant rise in dopamine release, shows study

By monitoring a well-replicated biomarker associated with reward, a study by neuroscientists from Florida Atlantic University provides evidence that the old adage, "There's no place like home," has its roots deep in the brain.

12 Nov 2020

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death.

11 Nov 2020

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Both of Andrew Kiselica's grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother's father become unable to walk or speak due to severe dementia.

11 Nov 2020

Severe obstructive sleep apnea linked to increased risk of dementia

A new study by Monash University has found that obstructive sleep apnea (OSA) has been linked to an increased risk of dementia.

11 Nov 2020

Study: Retired professional athletes may not suffer more severe cognitive impairment than others

Even though repeated hits to the head are common in professional sports, the long-term effects of concussions are still poorly understood.

11 Nov 2020

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Microglia -- the brain's immune cells -- play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, is also involved in removing debris as a backup to microglia.

11 Nov 2020

“Molecular volume knob” in the brain helps with learning, memory

A "molecular volume knob" regulating electrical signals in the brain helps with learning and memory, according to a Dartmouth study.

11 Nov 2020

Psychological factors are linked to incorrect fall risk perception in dementia patients

Dementia is associated with an impaired self-perception with potentially harmful consequences for health status and clinical risk classification in this patient group with an extraordinary high risk of falling.

11 Nov 2020

Study focuses on efficacy of cognitive rehabilitation across a range of neurological conditions

A new text by Kessler Foundation scientists focuses on the efficacy of cognitive rehabilitation across a variety of neurological conditions, with specific emphasis on treatment-related changes in the brain detectable via neuroimaging.

11 Nov 2020

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

St Petersburg University researchers, led by Professor Raul R. Gainetdinov, Director of the Institute of Translational Biomedicine and Academic Supervisor of the St Petersburg University Hospital, have found a new role for recently discovered neurotransmitter system that uses the trace amine-associated receptor 5 (TAAR5) for neurotransmission.

11 Nov 2020

Nanoparticles could treat neurodegenerative diseases, shows study

Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.

10 Nov 2020

Researchers investigate natural compound for treating amnestic Mild Cognitive Impairment

Greek researchers and clinicians investigated for the first time the effect of High Phenolic Early Harvest Extra Virgin Olive Oil (HP-EH-EVOO) versus Moderate Phenolic (MP-EVOO) and Mediterranean Diet (MeDi) as a therapeutic pharmaceutical natural compound for older adults with amnestic Mild Cognitive Impairment (aMCI).

10 Nov 2020

Research explores links between Alzheimer's and Parkinson′s to COVID-19

In a recent medRxiv* preprint paper, Dr. L. Miguel Martins and colleagues from the University of Cambridge investigate the links between neurodegeneration and COVID-19.

9 Nov 2020

Virginia Tech professor expands caregiving study during COVID-19 pandemic

Toni Calasanti was conducting a study on older adults who care for spouses or partners with Alzheimer's disease or dementia when the COVID-19 pandemic took hold in the United States.

9 Nov 2020

Study shows oxidant hydrogen peroxide can actually slow down cell ageing

At high concentrations, reactive oxygen species - known as oxidants - are harmful to cells in all organisms and have been linked to ageing.

9 Nov 2020

Researchers analyze metrics of cognitive decline in diverse Latinx populations

Alzheimer's disease and related dementias (ADRD) are degenerative brain diseases that affect over 5.8 million people in the U.S. Rates of ADRD are higher among Black and Latinx individuals compared to non-Latinx white individuals.

9 Nov 2020

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

6 Nov 2020

Researchers gain novel insights into the role of autophagy in neurons

It appears that autophagy protects our neurons in the brain, but evidently for entirely different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have now shown.

5 Nov 2020

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

5 Nov 2020

NIH awards grant totaling $19.5M for Down syndrome research project

Scientists and data experts are joining forces to create the world's first centralized platform for Down syndrome researchers to share, access, and analyze data.

5 Nov 2020

Alzheimer's Disease News and Research

Further Reading

Return of mice to home cage evokes significant rise in dopamine release, shows study

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Severe obstructive sleep apnea linked to increased risk of dementia

Study: Retired professional athletes may not suffer more severe cognitive impairment than others

Study may lead to new therapies that accelerate removal of cellular debris from the brain

“Molecular volume knob” in the brain helps with learning, memory

Psychological factors are linked to incorrect fall risk perception in dementia patients

Study focuses on efficacy of cognitive rehabilitation across a range of neurological conditions

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

Nanoparticles could treat neurodegenerative diseases, shows study

Researchers investigate natural compound for treating amnestic Mild Cognitive Impairment

Research explores links between Alzheimer's and Parkinson′s to COVID-19

Virginia Tech professor expands caregiving study during COVID-19 pandemic

Study shows oxidant hydrogen peroxide can actually slow down cell ageing

Researchers analyze metrics of cognitive decline in diverse Latinx populations

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

Researchers gain novel insights into the role of autophagy in neurons

HKUST researchers identify new therapeutic targets for Alzheimer's disease

NIH awards grant totaling $19.5M for Down syndrome research project

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