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Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Powerful microscopy tool sheds light on the origins of arterial biomass in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare and incurable disease of the lung arteries that causes early death.

20 Jan 2023

Research reveals the cellular origin of cancer-associated fibroblasts

A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows.

20 Jan 2023

InDevR raises $9 million in series B financing and partners with bioMérieux

New partnerships will drive the commercial expansion of InDevR’s game-changing solutions for vaccines and biotherapeutics.

20 Jan 2023

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

In this interview, News-Medical spoke to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer.

20 Jan 2023

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

In this interview, News Medical spoke to Kate Lawrenson, Ph.D., about their latest research which detailed the molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

19 Jan 2023

UQ researchers identify a cellular pathway to reprogram the body’s immune system

University of Queensland researchers have identified a pathway in cells that could be used to reprogram the body's immune system to fight back against both chronic inflammatory and infectious diseases.

18 Jan 2023

What does the future of clinical trials and evidence-based medicine look like?

In a recent perspective published in Nature Medicine, the researcher shared his vision and future perspectives for the domains of clinical research and evidence-based therapeutics.

18 Jan 2023

What older Americans need to know about taking Paxlovid

A new coronavirus variant is circulating, the most transmissible one yet. Hospitalizations of infected patients are rising. And older adults represent nearly 90% of U.S. deaths from covid-19 in recent months, the largest portion since the start of the pandemic.

18 Jan 2023

Researchers explore immune responses to mpox infections

In new research, researchers demonstrated that individuals recovering from mpox virus (MPXV) infection have neutralizing antibodies that target MPXV antigens A35R and H3L.

17 Jan 2023

TTP introduces Cellular Origins, a TTP Company focussed on delivering scalable manufacture of cell and gene therapies

New company created to enable commercial manufacture of new cell and gene therapies.

From TTP plc 17 Jan 2023

New molecular pathway critical to the initiation of pancreatic tumors discovered

Researchers at University of California San Diego School of Medicine have discovered a molecular pathway critical to the initiation of pancreatic tumors.

16 Jan 2023

Participants using Huma's clinical trial platform have high levels of engagement in COVID-19 study

Huma Therapeutics Limited ("Huma"), a leading global digital health company, today announced results of a new study in collaboration with the Medical Research Council Epidemiology Unit at the University of Cambridge showing that participants using Huma's clinical trial platform had high, sustained levels of engagement in an observational, fully remote COVID-19 study.

13 Jan 2023

New research identifies natural compounds with pan-SARS-CoV-2 inhibitory activity

Scientists have recently conducted a cell-based high-content screening of over 300 natural compounds and identified three compounds with potent antiviral activities against SARS-CoV-2 and its variants.

12 Jan 2023

Pheno Therapeutics announces worldwide license from UCB to a novel program for neurodegenerative disease

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics that promote remyelination for the treatment of neurological diseases such as multiple sclerosis, announced today it has entered into an exclusive worldwide license agreement with UCB.

12 Jan 2023

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Oregon State University College of Pharmacy scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

A recent study used generative AI models to develop de novo design antibodies against three distinct targets in a zero-shot fashion.

11 Jan 2023

UC researcher focuses on studying how gene mutations help pancreatic cancer grow

Only about 11% of people will survive five years after the detection of advanced pancreatic cancer. Such a low rate of success in treating pancreatic cancer is due to its late detection and an incomplete understanding of the disease development processes.

10 Jan 2023

Older adults with greater severity of hearing loss more likely to have dementia, study finds

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that older adults with greater severity of hearing loss were more likely to have dementia, but the likelihood of dementia was lower among hearing aid users compared to non-users.

10 Jan 2023

Therapeutics News and Research

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Powerful microscopy tool sheds light on the origins of arterial biomass in pulmonary arterial hypertension

Research reveals the cellular origin of cancer-associated fibroblasts

InDevR raises $9 million in series B financing and partners with bioMérieux

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

UQ researchers identify a cellular pathway to reprogram the body’s immune system

What does the future of clinical trials and evidence-based medicine look like?

What older Americans need to know about taking Paxlovid

Researchers explore immune responses to mpox infections

TTP introduces Cellular Origins, a TTP Company focussed on delivering scalable manufacture of cell and gene therapies

New molecular pathway critical to the initiation of pancreatic tumors discovered

Participants using Huma's clinical trial platform have high levels of engagement in COVID-19 study

New research identifies natural compounds with pan-SARS-CoV-2 inhibitory activity

Pheno Therapeutics announces worldwide license from UCB to a novel program for neurodegenerative disease

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

UC researcher focuses on studying how gene mutations help pancreatic cancer grow

Older adults with greater severity of hearing loss more likely to have dementia, study finds

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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