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ESCAPE-MeVO trial advances understanding of stroke treatment for medium-sized vessel blockages

University of Calgary's Hotchkiss Brain Institute researchers with the Calgary Stroke Program at Foothills Medical Centre revolutionized treatment for stroke with the ESCAPE Trial, proving that a clot retrieval procedure known as endovascular thrombectomy (EVT) can dramatically improve patient outcomes after an acute ischemic stroke caused by a blockage in a large-sized blood vessel.

7 Feb 2025

Early immune system changes contribute to lung damage in cystic fibrosis

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the disease causes changes in the immune system early in life, presumably even in newborns.

7 Feb 2025

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Breast cancer is the world's most prevalent cancer. Although earlier detection and targeted treatment have resulted in high survival rates, many breast cancer survivors experience fear of cancer recurrence. For some survivors this fear is occasional, for others it is persistent and often debilitating.

7 Feb 2025

Dispensary warning signs about cannabis use during pregnancy found ineffective

Warning signs at dispensaries about the potential health effects of cannabis use in pregnancy may not be effective, according to a new report in the Journal of Studies on Alcohol and Drugs, based at Rutgers University.

6 Feb 2025

US aid freeze puts HIV treatment in Africa at risk

Milicent Muyoma has been turned away twice from the clinic where she collects her HIV medication in Mathare, an informal settlement in Nairobi, Kenya.

6 Feb 2025

New method for detecting inflammation could revolutionize disease diagnosis

Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.

6 Feb 2025

New study identifies potential drug targets for heart failure

Heart failure remains a substantial burden for patients due to its high prevalence and limited therapeutic options. Heart failure is classified into two major clinical subtypes- heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF).

6 Feb 2025

RUFY1-RET fusion identified as mechanism of resistance to lorlatinib in lung cancer

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report."

6 Feb 2025

Testosterone found to worsen heart attack damage

Testosterone worsens the damage caused by a heart attack by increasing the number of white blood cells released from the bone marrow.

6 Feb 2025

Jumbo phages' protective shield offers clues for fighting antibiotic resistance

Scientists are learning more about how an intriguing type of virus protects itself. Revealing its strategies could boost the fight against antibiotic resistance.

6 Feb 2025

Biden rule cleared hurdles to lifesaving HIV drug, but in Georgia barriers remain

Latonia Wilkins knows she needs to be on PrEP due to her non-monogamous lifestyle. But the 52-year-old Atlanta mother has faced repeated challenges getting the lifesaving drug that can prevent new HIV infections.

6 Feb 2025

Communication between body muscle and pituitary gland may play unexpected role in female fertility

A newly discovered line of communication between body muscle and the pituitary gland may play an unexpected role in female fertility, according to a new study.

6 Feb 2025

Cervical cancer during pregnancy linked to higher maternal health risks

A new research paper was published in Oncoscience's Volume 12 on January 20, 2025, titled "Maternal, delivery and neonatal outcomes in women with cervical cancer. A study of a population database."

6 Feb 2025

Ethnicity and mental health impact brain health in rural older adults

A new research paper was published in Aging (Aging-US) on November 27, 2024, in Volume 17, Issue 1, titled "Neurocognitive disparities: investigating ethnicity and mental health in rural aging adults."

6 Feb 2025

Research disproves persister bacteria as main cause of antibiotic resistance

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study published in the journal Nature, researchers from the University of Basel challenge the conventional view that a small subset of particularly resilient bacteria are responsible for the failure of antibiotic therapies.

5 Feb 2025

Inhibiting S6K2 gene offers potential treatment for drug-resistant melanoma

The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. .

5 Feb 2025

No extra benefit from mechanical clot removal over medications in some strokes

Removing a clot blocking a medium- or small-sized artery in the brain mechanically is a safe treatment for a common type of stroke; however, it did not lessen disability more than best medical treatment (including clot-busting medication if indicated) alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

5 Feb 2025