Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Ultrasound technique provides a new way to diagnose circulation problems in the placenta

A team of researchers funded by the National Institutes of Health has developed a new ultrasound technique to monitor the placenta for impaired fetal blood flow early in pregnancy.

5 May 2021

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Despite decades of research and investment, the genetic underpinnings of Alzheimer's disease are still largely unknown, stymieing drug development and early diagnosis efforts.

5 May 2021

Key mechanism behind mutant p53 aggregation process is linked to cancer pathology

Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of malignant tumors.

5 May 2021

Study identifies novel combination therapy to help patients with advanced lung cancer

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a novel combination therapy to potentially help overcome resistance to immunotherapy in people diagnosed with advanced lung cancer.

5 May 2021

$3.5 million grant awarded to address the underrepresentation of Black adults in Alzheimer's research

Black adults are more likely than other groups to develop Alzheimer's disease or related disorders but are poorly represented in Alzheimer's disease research, including recent clinical trials. This health disparity illustrates how Black individuals can benefit from advances in the field if they had access.

4 May 2021

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Scientists from several hospitals and research centers have shown what happens in individual cells of patients who died of COVID-19. In a study published in Nature, the researchers describe how infected cells from multiple organs exhibited a range of molecular and genomic changes.

3 May 2021

Novel method provides faster and more precise diagnostics in histopathology

Histology is the study of biological tissues at a microscopic level. Also called microscopic anatomy, histology is widely used to provide diagnosis of cancer and other diseases.

30 Apr 2021

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals.

30 Apr 2021

New study reveals mechanisms that result in lethal COVID-19

A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases.

30 Apr 2021

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

The brain possesses a complex architecture of functional networks as its information-processing machinery. Is the brain's network architecture itself a target of disease? If so, which networks are associated with which diseases? What can this tell us about the underlying causes of brain disorders?

29 Apr 2021

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

New model may explain the perplexing asymmetrical motor symptoms in Parkinson's disease

Parkinson's disease (PD) is characterized by slowness of movement and tremors, which often appear asymmetrically in patients.

28 Apr 2021

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

A new study describes a synthetic peptide used as a platform to generate protective adaptive cellular immunity to the virus in rhesus macaques, which are the gold standard for preclinical testing in humans.

28 Apr 2021

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

27 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

Cholestenone could be a new antibacterial drug against H. pylori

Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world's population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and malignant lymphoma of the stomach.

27 Apr 2021

Pathology News and Research

Further Reading

Ultrasound technique provides a new way to diagnose circulation problems in the placenta

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Key mechanism behind mutant p53 aggregation process is linked to cancer pathology

Study identifies novel combination therapy to help patients with advanced lung cancer

$3.5 million grant awarded to address the underrepresentation of Black adults in Alzheimer's research

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Novel method provides faster and more precise diagnostics in histopathology

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

New study reveals mechanisms that result in lethal COVID-19

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

New model may explain the perplexing asymmetrical motor symptoms in Parkinson's disease

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

Cholestenone could be a new antibacterial drug against H. pylori

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

New discovery could lead to more effective treatments for fatigue-inducing anemias

New AI-driven diagnostics technique could transform treatment for bowel cancer

University-industry partnership leads to a new rapid COVID-19 test

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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