B Cell News and Research

RSS

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Scientists uncover how gut bacteria and body clock work together to promote fat accumulation

UT Southwestern researchers have uncovered new clues about how gut bacteria and the body's circadian clock work together to promote body fat accumulation.

12 Sep 2017

Researchers reveal possible origin of cancer-associated fibroblasts

Researchers at Okayama University describe in Scientific Reports that cancer-associated fibroblasts — cells that play a key role in cancer progression — originate from cancer stem cells. Preventing cancer stem cells from transforming into cancer-associated fibroblast may be a promising approach towards cancer treatment.

12 Sep 2017

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Oncology researchers studying high-risk children's cancers have identified a protein that offers a likely target for immunotherapy--harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an antibody selectively zeroes in on cancer cells without harming healthy cells.

11 Sep 2017

Genome sequence cannot predict radiation resistance, say researchers

For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka "Conan the bacterium," can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

11 Sep 2017

Component of fire ant venom shows promise as a psoriasis treatment

In a new study involving laboratory mice, researchers have found that solenopsin and similar compounds could be beneficial for psoriasis.

11 Sep 2017

Study findings may have critical implications to boost efficacy of T cell-based therapies

T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy.

11 Sep 2017

UM SOM research identifies four pathogens responsible for majority of diarrheal illnesses

Each year, more than half a million deaths among children under five years of age around the world are caused by diarrheal diseases -- largely due to insufficient access to adequate hygiene, sanitation and clean drinking water.

11 Sep 2017

Human cell-based methods could better identify asthma-causing chemicals, research suggests

Chemicals that could potentially cause asthma through an immune reaction could be better identified with human cell- and computer-based test methods, according to a new research paper co-authored by the Physicians Committee's Kristie Sullivan, M.P.H., in Applied In Vitro Toxicology.

11 Sep 2017

Portuguese researchers reveal mechanism of nuclei movement within muscle cells

A group of researchers at Instituto de Medicina Molecular Lisboa has revealed the mechanism by which cellular nuclei reach their position within muscle cells.

11 Sep 2017

Researchers uncover new structural information on laminin-integrin interaction

While you are what you eat, cells are what they touch. The cells with which it interacts will determine a cell's function, shape, and in some cases even identity.

11 Sep 2017

Researchers discover major mechanism in development of liver cancer

Liver cancer is the second-leading cause of cancer-related death and represents the fastest rising cancer worldwide. In most cases, the tumor develops in patients with chronic liver disease.

11 Sep 2017

TSRI scientists confirm that quality control steps exist to protect production of proteins

The devil, as always, is in the details. The production of proteins is a complex process, made up of a series of smaller intricate biochemical steps that succeeds because of an equally complex number of quality controls. Without them, the process would irreparably break down and diseases like cancer would run rampant.

11 Sep 2017

A rare dementia gene runs in the family, but he’s fine — so far

John Janda knows he takes after his mother. At 68, the graying building contractor is sentimental, just as she was. He smiles indulgently as he shows off photos of his 9-month-old grandson; he tears up at the memory of losing his dad in a construction accident more than 40 years ago.

11 Sep 2017

Researchers create first realistic model of the heart to simulate arrhythmia

A group of researchers from MIPT and Ghent University(Belgium) has developed the first realistic model able to reproduce the complexity of the cardiac microstructure.

11 Sep 2017

Scientists develop new method to reconstruct biological processes using image data

Researchers at the Helmholtz Zentrum München have developed a new method for reconstructing continuous biological processes, such as disease progression, using image data. The study was published in ‘Nature Communications’.

11 Sep 2017

E-cigarettes associated with increased blood pressure, heart rate, and arterial stiffness, study reveals

A new study, presented at the European Respiratory Society International Congress, suggests that use of e-cigarettes with nicotine causes arterial stiffness in humans, and has significant consequences leading to risk of heart disease and stroke later in life.

11 Sep 2017

Regulatory T-cells can support fat depots in dealing with environmental challenges

Immunosuppressive regulatory T-cells play an important role in the functioning of adipose tissue. This is the discovery of scientists from the Helmholtz Diabetes Center at Helmholtz Zentrum München and the Technical University of Munich.

11 Sep 2017

Study: Chemoradiation should remain standard treatment for locally advanced cervical cancer

A 14-year randomised trial in more than 600 patients has concluded that chemoradiation should remain the standard treatment for patients with locally advanced cervical cancer. The findings are reported today at the ESMO 2017 Congress in Madrid. The trial demonstrated no improved disease-free survival with neoadjuvant chemotherapy followed by surgery.

11 Sep 2017

B Cell News and Research

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Old lab technique helps researchers better understand circular DNA

Scientists uncover how gut bacteria and body clock work together to promote fat accumulation

Researchers reveal possible origin of cancer-associated fibroblasts

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Genome sequence cannot predict radiation resistance, say researchers

Component of fire ant venom shows promise as a psoriasis treatment

Study findings may have critical implications to boost efficacy of T cell-based therapies

UM SOM research identifies four pathogens responsible for majority of diarrheal illnesses

Human cell-based methods could better identify asthma-causing chemicals, research suggests

Portuguese researchers reveal mechanism of nuclei movement within muscle cells

Researchers uncover new structural information on laminin-integrin interaction

Researchers discover major mechanism in development of liver cancer

TSRI scientists confirm that quality control steps exist to protect production of proteins

A rare dementia gene runs in the family, but he’s fine — so far

Researchers create first realistic model of the heart to simulate arrhythmia

Scientists develop new method to reconstruct biological processes using image data

E-cigarettes associated with increased blood pressure, heart rate, and arterial stiffness, study reveals

Regulatory T-cells can support fat depots in dealing with environmental challenges

Study: Chemoradiation should remain standard treatment for locally advanced cervical cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News