Aging News and Research

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Study identifies fPRDM16 as target for age-related pulmonary fibrosis

A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying the transcriptional regulator fPRDM16 as a potential therapeutic target.

25 Jun 2026

Preoperative HMB supplement improves liver regeneration quality after major surgery

Taking a supplement before a hepatectomy, a surgery in which part of the liver is removed, may help the organ recover more quickly and become more resistant to further damage.

25 Jun 2026

Targeting metabolic pathways could prevent relapse in KRAS-mutant cancers

Our cells rely on tightly regulated signaling pathways to control when they grow, divide, and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous.

25 Jun 2026

Study compares menopause symptom burden across different age groups

There has been a lot of discussion about how the age at menopause can affect menopause symptoms. A new study compared the prevalence and severity of menopause symptoms in women experiencing menopause around the average age of 51 years and those with premature ovarian insufficiency, showing similar symptom burden in the psychological and urogenital domains.

24 Jun 2026

Hidden costs push United States dementia toll to historic high

A new USC-led study finds Alzheimer's disease and related dementias will cost the United States an estimated $818 billion this year, driven largely by often-overlooked costs to persons living with dementia and family and friends providing their care.

24 Jun 2026

Faster biological aging may explain rising early-onset cancers

The link between biological aging and early-onset cancer risk offers crucial insights into generational health trends and potential preventive measures.

24 Jun 2026

USC study links modified Mediterranean diet to longer lifespan

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

23 Jun 2026

Lifetime estrogen exposure linked to improved brain health in women

Researchers from the University of Kansas have shown a link between reproductive hormone exposure throughout life and brain health in 459 women aged 65 to 80.

23 Jun 2026

Researchers identify molecular cause of age-related cognitive decline

A research team from University Hospitals, Case Western Reserve University and the Louis Stokes Cleveland VA Medical Center has identified a critical molecular cause of age-related cognitive decline, potentially paving the way for new treatments to protect brain health as we age.

23 Jun 2026

Accelerated biological aging may drive rising early-onset cancer risk

Cancer is often considered a disease of aging. Older adults are at higher risk because they have had more time to accumulate cellular damage that can trigger tumor formation.

22 Jun 2026

Psychological traits may uncover why Alzheimer’s biology differs between patients

In 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex. Neuroticism and loneliness were associated with molecular progression, while purpose in life showed subtype-specific inverse associations, suggesting psychological traits may align with Alzheimer’s biology beyond conventional neuropathology.

22 Jun 2026

Scientists trace cardiac aging to a fading regulator in heart muscle cells

Researchers mapped 442,239 single nuclei from nonfailing human hearts to chart how cardiac cells change from fetal development to older adulthood. The study identified PRDM16 as an age-declining cardiomyocyte regulator, with experimental evidence showing that restoring Prdm16 in aged mouse hearts improved systolic function and partly reversed aging-associated transcriptional patterns.

22 Jun 2026

New vaccines successfully boost frontline immune cells against HIV

T-cells are the immune system's frontline defenders with a crucial role in controlling HIV. In a milestone clinical trial published in the Journal of Clinical Investigation, researchers with the UNC Institute for Global Health and Infectious Diseases (IGHID) at the UNC School of Medicine have demonstrated that new vaccines can significantly boost T cells targeting the most vulnerable, conserved regions of HIV-areas considered key to effective immune control.

22 Jun 2026