Biotechnology News and Research

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Genome sequence cannot predict radiation resistance, say researchers

For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka "Conan the bacterium," can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

11 Sep 2017

Compounds in fermented fish paste inhibit enzyme involved in cholesterol synthesis

Compounds in a fermented fish paste used as a condiment in Indonesia efficiently inhibit an enzyme involved in cholesterol synthesis, reports a study published in the Pertanika journal Tropical Agricultural Science.

11 Sep 2017

New drug treatment linked to higher bladder compliance after spinal cord injury

Researchers have shown that compared to placebo, a drug treatment intended to prevent remodeling of the bladder wall and given within 48 hours after spinal cord injury (SCI) in dogs was associated with significantly higher bladder compliance.

7 Sep 2017

Research shows new method for rapidly producing antimalarial drug at industrial scale

Compared to smallpox or typhoid, malaria is proving one of the most challenging human diseases to eradicate - and so remains a real and constant danger to nearly half the world's population.

7 Sep 2017

New DNA sequencing technology measures effects of thousands of sequences on gene activity

When a gene is switched on, various stretches of DNA nearby act as 'control dials', influencing the level of activity and the amount of gene product that is made.

7 Sep 2017

Exploration of human genetics reveals new targets to combat heart disease

Again and again, it's the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.

7 Sep 2017

Testing Service Members for Heat Related Illnesses Before Combat

It is common to think that combat deployment is the most dangerous part of being a warfighter, and in many ways this is correct. However, warfighters need to do many things before they are cleared to deploy to combat zones. Most cases of exertional heat illness (EHI) reported in the U.S. military occur during non-combat activities, such as training regimens, ruck marches, and operational exercises.

From Physitemp Instruments LLC 6 Sep 2017

Researchers find mechanism that explains differences in skin’s responsiveness to heat, mechanical stimuli

Researchers at the Bluestone Center for Clinical Research at the New York University College of Dentistry (NYU Dentistry) have identified a novel molecular mechanism which explains why dark-skinned and light-skinned people respond differently to heat and mechanical stimulation.

6 Sep 2017

Researchers decode complex finger millet genome in high quality for first time

Finger millet has two important properties: The grain is rich in important minerals and resistant towards drought and heat.

5 Sep 2017

Mayo Clinic experts move closer to realizing clinical potential of senolytic drugs on aging

Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.

4 Sep 2017

New crowdfunding campaign aims to develop, test novel photographic biomarkers of aging in mice

The Biogerontology Research Foundation announces the launch of a crowdfunding campaign, MouseAge, to develop and test photographic biomarkers of ageing in mice in collaboration with scientists from Harvard University, University of Oxford, Youth Laboratories and Insilico Medicine.

31 Aug 2017

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds of individual tests and many, many thousands of dollars.

31 Aug 2017

Study reveals new opportunities for treatment of Type 2 diabetes

Bacteria may be responsible for more than we suspect. Especially when it comes to inflammatory diseases such as Type 2 diabetes.

29 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

Bioinformatics expert receives $12.8 million grant to continue to lead Diabetic Complications Consortium

Dr. Richard A. McIndoe, bioinformatics expert and associate director of the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia at Augusta University, has received a $12.8 million grant to continue to lead a national research initiative focused on reducing the complications of diabetes.

26 Aug 2017

Tumor irradiation may prolong survival of NSCLC patients undergoing novel chemotherapy formulation

Patients with unresectable, or inoperable, lung cancer are often given a dismal prognosis, with low rates of survival beyond a few years.

26 Aug 2017

UA Valley Fever Center For Excellence awarded NIH grant to accelerate vaccine development

The Valley Fever Center for Excellence at the University of Arizona College of Medicine - Tucson has been awarded a four-year, $4.8 million grant for research to speed development of a vaccine to combat Valley fever, the sometimes deadly respiratory illness caused by Coccidioides spores found in soils of the U.S. Southwest.

24 Aug 2017

Study of ticks and tick-borne diseases receive global boost

A unique scientific resource for the study of ticks and tick-borne diseases has moved to the University of Liverpool with exciting plans for international expansion.

24 Aug 2017

New clinical trial to test cancer drug in patients with advanced solid tumors

A clinical trial to test a new cancer drug in patients with advanced solid tumors, launches in four centers across the UK today (Wednesday), through Cancer Research UK's Center for Drug Development.

23 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

Biotechnology News and Research

Genome sequence cannot predict radiation resistance, say researchers

Compounds in fermented fish paste inhibit enzyme involved in cholesterol synthesis

New drug treatment linked to higher bladder compliance after spinal cord injury

Research shows new method for rapidly producing antimalarial drug at industrial scale

New DNA sequencing technology measures effects of thousands of sequences on gene activity

Exploration of human genetics reveals new targets to combat heart disease

Testing Service Members for Heat Related Illnesses Before Combat

Researchers find mechanism that explains differences in skin’s responsiveness to heat, mechanical stimuli

Researchers decode complex finger millet genome in high quality for first time

Mayo Clinic experts move closer to realizing clinical potential of senolytic drugs on aging

New crowdfunding campaign aims to develop, test novel photographic biomarkers of aging in mice

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

Study reveals new opportunities for treatment of Type 2 diabetes

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Bioinformatics expert receives $12.8 million grant to continue to lead Diabetic Complications Consortium

Tumor irradiation may prolong survival of NSCLC patients undergoing novel chemotherapy formulation

UA Valley Fever Center For Excellence awarded NIH grant to accelerate vaccine development

Study of ticks and tick-borne diseases receive global boost

New clinical trial to test cancer drug in patients with advanced solid tumors

Id genes found to play crucial role in heart development

Biotechnology eBook

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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