Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Inhibition of complement disrupts neurodegeneration, improves cognitive function in TBI patients

Traumatic brain injury (TBI) is a major cause of disability and a risk factor for early-onset dementia. The injury is characterized by a physical insult followed acutely by complement driven neuroinflammation.

9 Mar 2021

New approach can advance medical AI algorithms, reduce risks to patient privacy

Within the field of artificial intelligence (AI), deep learning is an area of rapid and high-impact innovation in the healthcare industry.

9 Mar 2021

Researchers explore 3D printing materials to print realistic aorta models

Personalized 3D printed models created from cardiac imaging data, mainly from cardiac CT images have been increasingly used in cardiovascular disease, primarily in the preoperative planning and simulation of complex surgical procedures, as well as medical education.

8 Mar 2021

Compounds in green and black tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

8 Mar 2021

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Cancers that are resistant to radiotherapy could be rendered susceptible through treatment with immunotherapy, a new study suggests.

8 Mar 2021

Impairments in immune response contribute to severe COVID-19

New research by a team of scientists at University Hospital RWTH Aachen in Germany and Erasmus Medical Centre in The Netherlands characterized changes in CD8+ T cells in response to SARS-CoV-2.

8 Mar 2021

A sneak peek of the current state and future use of artificial intelligence in pathology

Artificial intelligence can already scan images of the eye to assess patients for diabetic retinopathy, a leading cause of vision loss, and find evidence of strokes on brain CT scans.

8 Mar 2021

Study: Monoclonal antibody 'cocktail' effective against all known COVID-19 variants

A monoclonal antibody "cocktail" developed at Vanderbilt University Medical Center (VUMC) to neutralize the COVID-19 virus is effective against all known strains, or variants, of the virus, according to a report published in the journal Nature Medicine.

5 Mar 2021

New COVID-19 variants can evade antibodies that work against original form of the virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pancreatitis drug Camostat inhibits new SARS-CoV-2 activators identified in the upper respiratory tract. There are no therapeutics available that have been developed for COVID-19 treatment.

5 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

An international team of researchers has identified the CNNM4 protein as a key regulator of magnesium in the liver and potential therapeutic target for non-alcoholic fatty liver disease, according to a study published in the Journal of Hepatology.

4 Mar 2021

Study clarifies the role of collagen during pancreatic cancer development

Contrary to long-held beliefs, Type I collagen produced by cancer-associated fibroblasts may not promote cancer development but instead plays a protective role in controlling pancreatic cancer progression, reports a new study from researchers at The University of Texas MD Anderson Cancer Center.

4 Mar 2021

Researchers explore mutational signatures associated with exposure to microplastic pollutants

According to the World Health Organization, plastic products and their chemical derivatives present in the environment present public health concerns on a global scale and more exploration on the potential impact to human health is needed.

3 Mar 2021

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Researchers have investigated the effectiveness of a bioengineered miniprotein in protecting against SARS-CoV-2 infection in vivo. The researchers evaluated the miniprotein, LCB1, against SARS-CoV-2-mediated lung disease in human ACE2-expressing transgenic mice.

3 Mar 2021

Analytical Mass Spectrometry: How Did We Get Here, Where are We Going?

News-Medical interviews Rick Yost, winner of the Pittsburgh Analytical Chemistry Award 2021, about his research into mass spectrometry.

From Pittcon 3 Mar 2021

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

The SARS-CoV-2 plasma viremia has been linked to severe disease and death in COVID-19 cases in small-scale cohort studies. The current study, published on the pre-print server medRxiv, aimed to study the mechanisms behind this relationship.

2 Mar 2021

SARS-CoV-2 UK variant shows low virulence and high shedding in hamster model

A new study compares the pathogenicity and infectiousness of one such variant, the VOC 202012/01 (B.1.1.7 lineage) from the United Kingdom, with the globally dominant D614G mutation-carrying strains.

2 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

New vaccination strategy could eliminate the bacteria that cause UTIs

Anyone who has ever developed a urinary tract infection (UTI) knows that it can be painful, pesky and persistent. UTIs have a high recurrence rate and primarily afflict women -- as many as 50% of women will experience at least one UTI during their lifetime.

1 Mar 2021

Pathology News and Research

Further Reading

Inhibition of complement disrupts neurodegeneration, improves cognitive function in TBI patients

New approach can advance medical AI algorithms, reduce risks to patient privacy

Researchers explore 3D printing materials to print realistic aorta models

Compounds in green and black tea relax blood vessels by activating ion channel proteins

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Impairments in immune response contribute to severe COVID-19

A sneak peek of the current state and future use of artificial intelligence in pathology

Study: Monoclonal antibody 'cocktail' effective against all known COVID-19 variants

New COVID-19 variants can evade antibodies that work against original form of the virus

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

Study clarifies the role of collagen during pancreatic cancer development

Researchers explore mutational signatures associated with exposure to microplastic pollutants

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Analytical Mass Spectrometry: How Did We Get Here, Where are We Going?

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

SARS-CoV-2 UK variant shows low virulence and high shedding in hamster model

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New vaccination strategy could eliminate the bacteria that cause UTIs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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