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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Amputation injury is reflected in bioelectric properties of opposing, undamaged limb

In research that extends knowledge about the physiology of regeneration and wound repair, Tufts University biologists have discovered that amputation of one limb is immediately reflected in the bioelectric properties of the contralateral, or opposing, undamaged limb of developing frogs.

5 Oct 2018

Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction, according to new research. Dysfunctional mitochondria, the energy centers of the cells, may contribute to fatigue and weakness that some people with breast cancer experience through the course of disease treatment.

5 Oct 2018

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Poor self-esteem associated with increased risk for opioid use

Health, family and romance problems appear to be the particular life stressors most associated with increased risk for using opioids to cope, and individuals with low self-esteem appear to be at risk for these connections, according to a new paper including researchers at Binghamton University, State University at New York.

3 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

World Stomach Day: International initiative to raise awareness and support for a vital organ

Tuesday, 2 October 2018 marks the first ever World Stomach Day, an international initiative to raise awareness and support for one of our most vital organs.

3 Oct 2018

Molecule research reveals potential drug target for treating stroke patients

In an extension of research published a month ago in Nature Methods, a novel hybrid approach performed by researchers from Clemson University's department of physics and astronomy and Stony Brook University has revealed a 3-D structure of a protein fragment that could serve as a drug target in treating stroke patients.

3 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Drop in estrogen could lead to development of anxiety and memory problems, finds study

Lack of estrogen may play a role in the development of anxiety and memory problems, according to a new rodent study.

1 Oct 2018

Philips introduces Ingenia Ambition X 1.5T MR with fully-sealed BlueSeal magnet for helium-free operations

Royal Philips, a global leader in health technology, today launched the Ingenia Ambition X 1.5T MR. Incorporating Philips’ breakthrough BlueSeal fully-sealed magnet, the Ingenia Ambition X is the world’s first MR system to enable helium-free operations, reducing the chance of potentially lengthy and costly disruptions, and virtually eliminating dependency on a commodity with an unpredictable supply.

From Philips Healthcare 1 Oct 2018

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation grant, and the results were published in Nature Methods.

28 Sep 2018

Study highlights role of non-mutational mechanism in myotonic dystrophy, other types of arrhythmias

A team of researchers at Baylor College of Medicine reveals new insights into what can be causing life-threatening cardiac-related events in myotonic dystrophy type 1.

28 Sep 2018

Researchers develop new mathematical technique to study brain waves

A U.S. Army Research Laboratory scientist has collaborated with a team of researchers from the University of North Texas to develop a new data processing technique that uses electroencephalogram, or EEG, time series variability as a measure of the state of the brain.

27 Sep 2018

UCI researchers receive $3.4 million grant to study new class of cancer killing immunotherapeutics

UCI School of Medicine researchers have been awarded a $3.4 million grant by the National Cancer Institute as part of the Beau Biden Cancer Moonshot initiative.

27 Sep 2018

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today positive topline results from the interim analysis of the ENVISION Phase 3 Study of givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1 for the treatment of acute hepatic porphyria.

27 Sep 2018

New cell-based profiling service from RBC and Promega

A new cell-based profiling service for drug discovery has been announced by RBC and Promega Corporation.

From Promega Corporation 27 Sep 2018

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

For patients diagnosed with a Staphylococcus aureus infection, often referred to as a staph or MRSA infection, every minute counts.

27 Sep 2018

Moffitt researcher awarded World Molecular Imaging Society's highest honor

Robert Gillies, Ph.D., chair of the Department of Cancer Physiology and vice chair of Radiology Research at Moffitt Cancer Center, was awarded the World Molecular Imaging Society's highest honor.

27 Sep 2018

Researchers to explore sex differences in cardiovascular and renal physiology

A person's sex can be a defining factor in how well--or how poorly--they respond to disease, therapy and recovery. Experts at the forefront of sex-specific research will convene next week at the sixth APS conference on sex differences in cardiovascular and renal physiology.

26 Sep 2018

Physiology News and Research

Amputation injury is reflected in bioelectric properties of opposing, undamaged limb

Study reveals factors linked to the development of Crohn's disease

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Poor self-esteem associated with increased risk for opioid use

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

World Stomach Day: International initiative to raise awareness and support for a vital organ

Molecule research reveals potential drug target for treating stroke patients

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Drop in estrogen could lead to development of anxiety and memory problems, finds study

Philips introduces Ingenia Ambition X 1.5T MR with fully-sealed BlueSeal magnet for helium-free operations

Researchers create photoswitchable fluorescent proteins with optical properties

Study highlights role of non-mutational mechanism in myotonic dystrophy, other types of arrhythmias

Researchers develop new mathematical technique to study brain waves

UCI researchers receive $3.4 million grant to study new class of cancer killing immunotherapeutics

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

New cell-based profiling service from RBC and Promega

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

Moffitt researcher awarded World Molecular Imaging Society's highest honor

Researchers to explore sex differences in cardiovascular and renal physiology

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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