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Cognitive decline may signal heart trouble years before a cardiovascular event

In a large ASPREE and ASPREE-XT nested case-control study of older adults without prior cardiovascular disease, people who later experienced a CVD event showed faster cognitive decline beginning roughly 3 to 8 years before the event. Processing speed declined earliest, suggesting that subtle cognitive changes may emerge well before overt cardiovascular disease.

21 Apr 2026

CAR-PRISM trial reports promising results in high-risk smoldering multiple myeloma

Results of the single-center, phase 2 CAR-PRISM (PRecision Intervention Smoldering Myeloma) clinical trial, the first to investigate Chimeric Antigen Receptor (CAR) T-cell therapy in patients with high-risk smoldering multiple myeloma, showed that all 20 patients were negative for minimal residual disease (MRD) within two months of treatment and remained MRD-negative after a median of 15.3 months of follow-up, and none experienced high-grade side effects, according to results presented at the AACR Annual Meeting 2026, held April 17-22, in San Diego, Calif.

21 Apr 2026

Oral bacteria can reveal your true biological age and health risks

A simple oral rinse may predict biological age, linking oral microbiome changes to aging, frailty, and chronic disease risk in a noninvasive manner.

21 Apr 2026

High-fat, low-carbohydrate diet may improve beta-cell function in patients with type 2 diabetes

People with type 2 diabetes on a high-fat, low-carbohydrate diet may have a better chance of reversing their diabetes than those on a low-fat diet, according to a small study published in the Journal of the Endocrine Society.

21 Apr 2026

Long-term exposure to air pollution (PM2.5) raises risk of developing cancer by 11 % and of dying from cancer by 12 %

The Union for International Cancer Control (UICC), with support from the Clean Air Fund, has released a global report, Clean air in cancer control: An overview of the evidence, presenting data on the scale of cancer risk and mortality from polluted air.

21 Apr 2026

Single CAR T infusion shows strong response in smoldering multiple myeloma patients

A single infusion of ciltacabtagene autoleucel (Carvykti) led to a 100% minimal residual disease (MRD)-negativity rate in patients with high-risk smoldering multiple myeloma, according to results from CAR-PRISM, a phase II clinical trial, presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

20 Apr 2026

Why heart risk is hard to predict in type 1 diabetes

A European study reveals cardiovascular risk patterns in type 1 diabetes, highlighting the need for tailored prevention strategies to catch complications early.

20 Apr 2026

Nature-inspired vesicles offer new path for precision medicine therapies

A quiet revolution is underway in modern medicine: Drug development is aiming to move from managing disease to correcting it through RNA and gene-editing therapies.

17 Apr 2026

Breakthrough blood test predicts kidney failure years before clinical symptoms

A new blood test can identify which individuals of African ancestry carrying high-risk APOL1 gene variants are most likely to develop kidney failure, years before clinical disease becomes apparent.

15 Apr 2026

Rural Nebraska dialysis unit closes despite the state’s $219M in rural health funding

The sun was just warming the horizon as Mark Pieper left his house near his cattle ranch on a crisp February morning.

15 Apr 2026

Metabolic syndrome doubles worldwide over two decades

A global study reveals a sharp rise in metabolic syndrome prevalence from 2000 to 2023, highlighting urgent public health challenges and regional disparities.

15 Apr 2026

Hepatologists effectively deliver palliative care to patients with liver disease

Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality of life.

13 Apr 2026

Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

The Medicines and Healthcare products Regulatory Agency (MHRA) has granted approval for Kerendia® (finerenone), a non-steroidal, selective mineralocorticoid receptor antagonist (nsMRA), for the treatment of symptomatic chronic heart failure (HF) with left ventricular ejection fraction (LVEF) ≥ 40 %, in adults in the UK.

From Bayer PLC 13 Apr 2026

Obesity health risks differ significantly between men and women

New research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May), reveals distinct patterns of heart, metabolic, and inflammatory health risks between men and women living with obesity, providing an insight into how clinicians may be able to tailor management approaches.

13 Apr 2026

Weight gain timing affects long-term health outcomes

When in life we gain weight can have a significant impact on our health many years later. In a study involving over 600,000 people, researchers at Lund University in Sweden have investigated how changes in weight between the ages of 17 and 60 are linked to the risk of dying from various diseases

11 Apr 2026

Man steps forward to donate kidney to unknown teen

Tim Fitzpatrick was at home on Long Island when he saw a local news story about a 13-year-old boy in need of a kidney transplant.

11 Apr 2026

More steps cut chronic disease risk but cannot fully undo long sitting

Research shows higher daily step counts can mitigate risks of chronic diseases linked to prolonged sitting, emphasizing the need to reduce sedentary time.

10 Apr 2026

Large US study finds never-married adults face higher risk for most major cancers

A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.

9 Apr 2026

Wireless ureteral stent sleeve enables early detection of hydronephrosis

Ureteral stents are widely used to relieve obstruction and protect kidney function, but they can also become blocked, triggering hydronephrosis and prolonged elevation of intrarenal pressure that may impair renal function.

9 Apr 2026

Neighborhood conditions linked to cellular aging and health disparities

There's a growing consensus that your zip code is a strong predictor of your health and lifespan. Now, researchers at NYU School of Global Public Health have determined that neighborhood conditions may be driving aging at the cellular level.

7 Apr 2026

Kidney News and Research

Cognitive decline may signal heart trouble years before a cardiovascular event

CAR-PRISM trial reports promising results in high-risk smoldering multiple myeloma

Oral bacteria can reveal your true biological age and health risks

High-fat, low-carbohydrate diet may improve beta-cell function in patients with type 2 diabetes

Long-term exposure to air pollution (PM2.5) raises risk of developing cancer by 11 % and of dying from cancer by 12 %

Single CAR T infusion shows strong response in smoldering multiple myeloma patients

Why heart risk is hard to predict in type 1 diabetes

Nature-inspired vesicles offer new path for precision medicine therapies

Breakthrough blood test predicts kidney failure years before clinical symptoms

Rural Nebraska dialysis unit closes despite the state’s $219M in rural health funding

Metabolic syndrome doubles worldwide over two decades

Hepatologists effectively deliver palliative care to patients with liver disease

Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

Obesity health risks differ significantly between men and women

Weight gain timing affects long-term health outcomes

Man steps forward to donate kidney to unknown teen

More steps cut chronic disease risk but cannot fully undo long sitting

Large US study finds never-married adults face higher risk for most major cancers

Wireless ureteral stent sleeve enables early detection of hydronephrosis

Neighborhood conditions linked to cellular aging and health disparities

Event guide: 8th CKD Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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