Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Digital pathology solution from Sectra used for training future pathologists

The Royal College of Pathologists of Australasia has reached a milestone in its exam process with trainees now using the digital pathology solution from the international medical imaging IT and cybersecurity company Sectra.

9 Nov 2020

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

In the study, published on the pre-print journal bioRxiv, the researchers revealed that SARS-CoV-2-infected EHTs manifested the typical characteristics of myocarditis or heart inflammation. These include the stimulation of immune cells, heart cell death, and decreased contractile force generation.

8 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

A team of researchers in Singapore, led by Dr. Joe Yeong, and Prof. Tony Kiat Hon Lim, have reported the presence of residual SARS-CoV-2 ribonucleic acid (RNA) – the virus' genetic material – in stool samples and gastrointestinal tissues from patients recovering from the coronavirus disease 2019 (COVID-19).

8 Nov 2020

Study identifies key clinical features of chronic nonbacterial osteomyelitis

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features of chronic nonbacterial osteomyelitis (CNO), which leads to an important step toward the development of much-needed classification criteria for a disease that affects children and young adults worldwide.

6 Nov 2020

Study opens a new avenue for prophylactic anti-malarial strategies

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 that is required for their entry into hepatocytes.

6 Nov 2020

Commonly prescribed anti-depressant may halt the growth of childhood sarcoma

A new study has found that a commonly prescribed anti-depressant may halt growth of a type of cancer known as childhood sarcoma, at least in mice and laboratory cell experiments.

6 Nov 2020

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

Pancreatic cancer is highly lethal: according to the National Cancer Institute, only about 10 percent of patients remain alive five years after diagnosis.

6 Nov 2020

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

A team of researchers recently investigated the genetic determinants of COVID-19 risk and severity in humans.

6 Nov 2020

Unrelated mutations can lead to false-positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false-positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

5 Nov 2020

Persistent and extensive lung damage seen in COVID-19 patients

A team of researchers at the University of Trieste in Italy aimed to determine the extent and the causes of lung damage from COVID-19 to better understand the pathological correlates of the disease.

5 Nov 2020

Children produce different antibodies in response to infection with new coronavirus

Children and adults produce different types and amounts of antibodies in response to infection with the new coronavirus, SARS-CoV-2, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

5 Nov 2020

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

5 Nov 2020

Experts release new guidance for endoscopists on how to assess colorectal lesions

Early identification and removal of cancerous colorectal polyps is critical to preventing the progression of colorectal cancer and improving survival rates.

4 Nov 2020

Eye's cornea can resist infection from novel coronavirus

New findings from researchers at Washington University School of Medicine in St. Louis suggest the eye's cornea can resist infection from the novel coronavirus.

3 Nov 2020

Blood vessel malformations originate in vein cells

In the condition known as cavernoma, lesions arise in a cluster of blood vessels in the brain, spinal cord or retina. Researchers from Uppsala University can now show, at molecular level, that these changes originate in vein cells.

3 Nov 2020

SARS-CoV-2 virus may target red marrow and prevent the formation of new erythrocytes

Specialists from the Department of Fundamental Medicine of Far Eastern Federal University (FEFU) with Russian and Japanese colleagues have probed into mechanisms of COVID-19 inside-the-body distribution linked to erythrocytes damaging.

30 Oct 2020

Experts call for transformative change to reduce future pandemics

Future pandemics will emerge more often, spread more rapidly, do more damage to the world economy and kill more people than COVID-19 unless there is a transformative change in the global approach to dealing with infectious diseases, warns a major new report on biodiversity and pandemics by 22 leading experts from around the world.

30 Oct 2020

SARS-CoV-2 spike proteins can directly impact the blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Pathology News and Research

Further Reading

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Digital pathology solution from Sectra used for training future pathologists

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

Study identifies key clinical features of chronic nonbacterial osteomyelitis

Study opens a new avenue for prophylactic anti-malarial strategies

Commonly prescribed anti-depressant may halt the growth of childhood sarcoma

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

Unrelated mutations can lead to false-positive results in men with advanced prostate cancer

Persistent and extensive lung damage seen in COVID-19 patients

Children produce different antibodies in response to infection with new coronavirus

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Experts release new guidance for endoscopists on how to assess colorectal lesions

Eye's cornea can resist infection from novel coronavirus

Blood vessel malformations originate in vein cells

SARS-CoV-2 virus may target red marrow and prevent the formation of new erythrocytes

Experts call for transformative change to reduce future pandemics

SARS-CoV-2 spike proteins can directly impact the blood-brain barrier

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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