Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

Debate over a dying child and a lack of transplant organs

Several columnists explore the difficult questions raised by the case of Sarah Murnaghan, a 10-year-old with cystic fibrosis who needs a lung transplant to survive.

10 Jun 2013

Discovery highlights protective role of liver enzyme in treating jaundice

Helping to protect newborns and older patients against more severe effects of jaundice is the hope of University of Guelph researchers, who have shown how a liver enzyme protects cells from damage caused by the condition.

10 Jun 2013

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Concert Pharmaceuticals, Inc. today announced that it has initiated a Phase 1 clinical trial with CTP-354. CTP-354 is a novel GABAA receptor subtype-selective modulator that has demonstrated no sedation at therapeutic doses in preclinical models in contrast to existing GABAA receptor non-selective agonists, such as benzodiazepines.

10 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Brain-training computer games may help restore memory and competency to forensic psychiatry patients in state mental hospitals, researchers say.

10 Jun 2013

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Edge Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products for acute, fatal or debilitating conditions, announced today that the U.S. Food and Drug Administration has accepted the Company's Investigational New Drug application for EG-1962, a novel bio-absorbable nimodipine microparticle formulation.

10 Jun 2013

Poll reveals that half of Canadians are directly touched by stroke

More Canadians are surviving strokes due to advances in awareness and medical services but a new report by the Heart and Stroke Foundation reveals that more than one-third of Canadians mistakenly believe that the recovery period is limited to a few months.

10 Jun 2013

First consensus guidelines for use of neurostimulation in chronic pain

Recognizing that treatment of chronic pain can be confounding, the Neuromodulation Appropriateness Consensus Committee, an international group of more than 60 leading pain specialists, has created the first consensus guidelines for the use of neurostimulation in chronic pain.

10 Jun 2013

International experts formulate guidance for neuromodulation practitioners

An international panel of experts has formulated guidance for neuromodulation practitioners that reflects increasing recognition of the value of this growing field.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Summa Akron City Hospital installs Toshiba's Aquilion ONE, Infinix-i systems

As a level-one trauma and accredited stroke center, time is critical at Summa Health System's Akron City Hospital, located in Akron, Ohio. To provide the highest level of patient care, the hospital installed an Aquilion ONE CT scanner and Infinix-i bi-plane cardiovascular X-ray from Toshiba America Medical Systems, Inc.

10 Jun 2013

Nation's leading experts join forces to accelerate effective treatments for brain tumors

The nation's leading brain tumor and biotech industry experts again joined forces Friday, June 7, in a bid to accelerate more effective treatments for brain tumors and promote funding for the latest emerging therapies, as the Weill Cornell Brain and Spine Center and Voices Against Brain Cancer hosted its second annual Brain Tumor Biotech Summit.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

Study sheds light on origin of wide range of brain disorders

Researchers at Weill Cornell Medical College have uncovered a mechanism that guides the exquisite wiring of neural circuits in a developing brain -- gaining unprecedented insight into the faulty circuits that may lead to brain disorders ranging from autism to mental retardation.

10 Jun 2013

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Difficult-to-study diseases such as Alzheimer's, schizophrenia, and autism now can be probed more safely and effectively thanks to an innovative new method for obtaining mature brain cells called neurons from reprogrammed skin cells. According to Gong Chen, the Verne M. Willaman Chair in Life Sciences and professor of biology at Penn State University and the leader of the research team, "the most exciting part of this research is that it offers the promise of direct disease modeling, allowing for the creation, in a Petri dish, of mature human neurons that behave a lot like neurons that grow naturally in the human brain."

10 Jun 2013

Large study of deep brain stimulation underway for Alzheimer's disease treatment

Together, Butler Hospital and Rhode Island Hospital are participating in The ADvance Study, a clinical trial investigating the use of deep brain stimulation as a treatment for patients with Alzheimer's disease.

10 Jun 2013

Brain News and Research

Further Reading

Researchers find master regulator of EMT and metastasis

Debate over a dying child and a lack of transplant organs

Discovery highlights protective role of liver enzyme in treating jaundice

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Common antidepressant medications may impair a form of learning, new report suggests

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Poll reveals that half of Canadians are directly touched by stroke

First consensus guidelines for use of neurostimulation in chronic pain

International experts formulate guidance for neuromodulation practitioners

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Summa Akron City Hospital installs Toshiba's Aquilion ONE, Infinix-i systems

Nation's leading experts join forces to accelerate effective treatments for brain tumors

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Scientists discover how Arc protein helps translate learning into memory

Study sheds light on origin of wide range of brain disorders

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Large study of deep brain stimulation underway for Alzheimer's disease treatment

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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