Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

COVID-19-related myocarditis may be a relatively rare occurrence, indicates study

A study conducted by Richard Vander Heide, MD, PhD, Professor and Director of Pathology Research at LSU Health New Orleans School of Medicine, and Marc Halushka, MD, PhD, Professor of Pathology at Johns Hopkins University School of Medicine, suggests myocarditis caused by COVID-19 may be a relatively rare occurrence.

30 Oct 2020

COVID-19 study: Researchers recruit frontline workers to identify asymptomatic individuals

Fifteen hundred frontline workers are being recruited for a yearlong study to find what percentage are positive for the virus that causes COVID-19, what percentage become positive and whether the antibodies they produce protect them from reinfection.

30 Oct 2020

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

Now, a team of researchers at the University of Florida report that the SARS-CoV-2 viroporin triggers the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome, which is responsible for the inflammatory pathology in severely ill COVID-19 patients.

30 Oct 2020

New method could help increase effectiveness of vaccines against coronavirus

A University at Buffalo-led research team has discovered a technique that could help increase the effectiveness of vaccines against the novel coronavirus, the virus that causes COVID-19.

29 Oct 2020

Majority of people infected with mild-to-moderate COVID 19 mount robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease. In order for this tau pathology to spread, the protein must interact with heparan sulfate, a sugar molecule found on the surface of neurons.

28 Oct 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

Scientists compare ACE2 interaction with SARS-CoV-2 across species

Like other pathogenic coronaviruses, SARS-CoV-2 crossed the species barrier to cause human disease. This fact motivated the current study, published on the preprint server bioRxiv* in October 2020, which explores the way coronaviruses engage their host cell receptors in a range of animals.

28 Oct 2020

Ultramicroscopy helps visualize tumor tissues in three dimensions

After cancer surgery, the crucial question is: Are there possibly cancer cells left behind that can continue to grow, or has the entire tumor actually been removed? To find out, the tumor is examined by pathologists.

28 Oct 2020

Study: Coronaviruses are adept at imitating human immune proteins involved in COVID-19

Coronaviruses are adept at imitating human immune proteins that have been implicated in severe COVID-19 disease, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

28 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Study provides novel biomarkers for predicting rheumatoid arthritis patient responsiveness to DMARDs

A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs).

27 Oct 2020

Lung biomarkers may predict severe COVID-19

Two University of New Mexico researchers postulate certain specific biomarkers' relevance in predicting the potential for progression to severe COVID-19 in a paper published on the preprint server bioRxiv*

27 Oct 2020

Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

Pancreatic cancer has remained resistant to immunotherapies that are revolutionizing the treatment of many types of cancer.

27 Oct 2020

New tool predicts prognosis of individual patients with COVID-19

A new artificial intelligence-based score considers multiple factors to predict the prognosis of individual patients with COVID-19 seen at urgent care clinics or emergency departments.

27 Oct 2020

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

Huron Digital Pathology announced today that the Joint Pathology Center (JPC), the premier pathology reference center for the United States federal government and part of the US Defense Health Agency, has selected Huron’s artificial intelligence-enabled LagottoTM image search engine to index and search JPC’s growing digital image archive.

From Huron Technologies 26 Oct 2020

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

From Huron Technologies 23 Oct 2020

Study raises new questions about viral load in asymptomatic children with COVID-19

New questions are at the forefront as a study published in the Journal of Clinical Microbiology from nine children's hospitals finds that most asymptomatic children who tested positive for COVID-19 had relatively low levels of the virus compared to symptomatic children.

22 Oct 2020

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

The Alzheimer's Biomarkers Consortium - Down Syndrome, a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health, to expand research on the biomarkers of Alzheimer's disease in adults with Down syndrome.

22 Oct 2020

Study: More women with invasive breast cancer could potentially be spared an axillary surgery

More women could potentially be spared an axillary lymph node dissection -- the surgical removal of 10-20 lymph nodes -- a procedure that causes disabling arm swelling in up to 25% of women, according to a UCLA study led by Dr. Maggie DiNome, chief of breast surgery at the David Geffen School of Medicine at UCLA.

22 Oct 2020

Pathology News and Research

Further Reading

COVID-19-related myocarditis may be a relatively rare occurrence, indicates study

COVID-19 study: Researchers recruit frontline workers to identify asymptomatic individuals

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

New method could help increase effectiveness of vaccines against coronavirus

Majority of people infected with mild-to-moderate COVID 19 mount robust antibody response

Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Scientists compare ACE2 interaction with SARS-CoV-2 across species

Ultramicroscopy helps visualize tumor tissues in three dimensions

Study: Coronaviruses are adept at imitating human immune proteins involved in COVID-19

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

Study provides novel biomarkers for predicting rheumatoid arthritis patient responsiveness to DMARDs

Lung biomarkers may predict severe COVID-19

Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

New tool predicts prognosis of individual patients with COVID-19

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

Study raises new questions about viral load in asymptomatic children with COVID-19

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

Study: More women with invasive breast cancer could potentially be spared an axillary surgery

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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