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Gut enzyme discovery sheds light on bilirubin balance in humans

Researchers study identified BilR, a gut microbiota-derived enzyme, crucial for converting bilirubin to urobilinogen, impacting bilirubin homeostasis in humans.

7 Jan 2024

Inhalable point-of-care urinary diagnostic platform for early lung cancer detection

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.

5 Jan 2024

New app helps patients with alcohol-related liver disease recover, saves lives

A mobile phone app which helps patients with alcohol-related liver disease to stay sober could help save hundreds of lives every year, according to researchers from UCL and the Royal Free Hospital who developed the app.

5 Jan 2024

Breakthrough drug halts lung cancer and brain metastases

D'Or Institute for Research and Education (IDOR) played an important role in the phase III LIBRETTO-431 multicenter study, which evaluated the efficacy and safety of selpercatinib compared to control treatment, which consisted of platinum-based chemotherapy associated or not with pembrolizumab (immune checkpoint inhibitor) in non-small cell lung cancer (NSCLC).

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

4 Jan 2024

Gut microbes revealed as key players in liver disease solutions

In the editorial published on 4 September 2023, in the "gut-liver axis" special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota in various liver diseases.

4 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

Simple technique boosts antibody delivery for treating brain diseases

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

3 Jan 2024

Natural compounds show promise in modulating heme breakdown, offering new therapeutic avenues

Study explores the impact of natural compounds on bilirubin production and heme catabolic pathway modulation, highlighting their potential in treating neurodegenerative and cardiovascular diseases.

3 Jan 2024

Study: High-fat diets impact genes in the intestines, brain, and immune system

A UC Riverside study to motivate your new year's resolutions: it demonstrates that high-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Researchers identify microbial enzyme responsible for making urine yellow

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

3 Jan 2024

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Whether a polyphenol found in green tea, reduces inflammation.

3 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

AI advances could revolutionize hepatocellular carcinoma diagnosis

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is a major global health concern with rising rates, particularly in North Africa and East Asia.

28 Dec 2023

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Liver News and Research

Gut enzyme discovery sheds light on bilirubin balance in humans

Inhalable point-of-care urinary diagnostic platform for early lung cancer detection

New app helps patients with alcohol-related liver disease recover, saves lives

Breakthrough drug halts lung cancer and brain metastases

Unlocking the power of diet: How miRNAs influence health and disease

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

Gut microbes revealed as key players in liver disease solutions

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Simple technique boosts antibody delivery for treating brain diseases

Natural compounds show promise in modulating heme breakdown, offering new therapeutic avenues

Study: High-fat diets impact genes in the intestines, brain, and immune system

"Genetic priority score" promises to revolutionize drug development

Researchers identify microbial enzyme responsible for making urine yellow

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Exploring the global health challenge of hepatitis D

Brain receptor discovery opens door to new therapies for addiction and mental health

AI advances could revolutionize hepatocellular carcinoma diagnosis

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

New drug screening system helps uncover promising target for pancreatic cancer treatments

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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