Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Breakfast may lower risk of diabetes and heart disease, study says

A new study published in the Journal of Physiology suggests that regularly consuming breakfast affects our body fat cells by lowering the activity of genes involved in fat metabolism and increasing the amount of sugar they use up. According to the study, this may reduce the risk of diabetes and cardiovascular disease.

5 Dec 2017

Impaired respiratory function in people born prematurely could be due to smaller airways

People born prematurely may have smaller airways than those born at full term, which can cause respiratory problems. That’s according to research published in Experimental Physiology today.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

Innovative nanoparticle-based approach to fight myocardial infarction

How can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells? A research team under the supervision of the University of Bonn is now presenting an innovative method on mice: Muscle replacement cells, which are to take over the function of the damaged tissue, are loaded with magnetic nanoparticles.

1 Dec 2017

Research suggests general mechanism by which dietary fats affect cellular physiology

You are what you eat when it comes to fat, report scientists from McGovern Medical School at The University of Texas Health Science Center at Houston in the journal Science Advances.

1 Dec 2017

Prenatal maternal stress affects size of the baby, study finds

A new study has been published that suggests babies are physically affected by the stress level of their mother during pregnancy. It has been previously found that adversity in the womb enhances or hampers offspring development and performance.

29 Nov 2017

Regular exercise may protect smokers from muscle loss and inflammation

Regular exercise may protect smokers from some of the negative effects associated with smoking, such as muscle loss and inflammation, according to a new study.

28 Nov 2017

Rod photoreceptors in the retina contribute to daylight vision, new study shows

An international research team headed by Thomas Münch of the Institute for Ophthalmic Research and Werner Reichardt Centre for Integrative Neuroscience of the University of Tübingen found the contribution of rod photoreceptors in mouse retinas to be much greater than previously assumed. One cannot distinguish colors with rods.

28 Nov 2017

Intestinal epithelial stem cells may provide new insights into behavior of cancer cells

The lining of the intestines - the epithelium - does more than absorb nutrients from your lunch. It grows, shrinks, and adjusts the very makeup of its cells in response to whatever you just ate. And understanding that process might just give scientists new insights into the behavior of cancer cells.

28 Nov 2017

Flies could act as autonomous bionic drones to help monitor disease outbreaks

An international research team led by Nanyang Technological University, Singapore have proposed that swarms of flies can be used to help monitor disease outbreaks.

25 Nov 2017

Researchers find no signs of early-onset OA in radiographs of Dolly's skeleton

Original concerns that cloning caused early-onset osteoarthritis (OA) in Dolly the sheep are unfounded, say experts at the University of Nottingham and the University of Glasgow.

23 Nov 2017

High-fat diet during lactation alters RNA activity in breast milk, research suggests

New research suggests that following a high-fat diet during lactation - regardless of diet during pregnancy - alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.

21 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

New research finds out how cinnamon may help fight against obesity

New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice--cinnamon--might be enlisted in the fight against obesity.

21 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

Combining calorie-restricted diet with high-intensity exercise could help reduce risk of weight regain

Researchers at the University of Alabama at Birmingham have found that combining a calorie-restricted diet with high-intensity interval training could be a solution for reducing weight regain after weight loss.

16 Nov 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

New research shows how a gene can fuel obesity in mice

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.

16 Nov 2017

Physiology News and Research

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Breakfast may lower risk of diabetes and heart disease, study says

Impaired respiratory function in people born prematurely could be due to smaller airways

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Study reveals gene linked to metastatic melanoma

Innovative nanoparticle-based approach to fight myocardial infarction

Research suggests general mechanism by which dietary fats affect cellular physiology

Prenatal maternal stress affects size of the baby, study finds

Regular exercise may protect smokers from muscle loss and inflammation

Rod photoreceptors in the retina contribute to daylight vision, new study shows

Intestinal epithelial stem cells may provide new insights into behavior of cancer cells

Flies could act as autonomous bionic drones to help monitor disease outbreaks

Researchers find no signs of early-onset OA in radiographs of Dolly's skeleton

High-fat diet during lactation alters RNA activity in breast milk, research suggests

Simple test could help predict best treatment for cystic fibrosis patients

New research finds out how cinnamon may help fight against obesity

New model to test effectiveness of existing and potential CF therapies

Combining calorie-restricted diet with high-intensity exercise could help reduce risk of weight regain

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

New research shows how a gene can fuel obesity in mice

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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