Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Small changes in one heart protein cause distinct cardiomyopathies

Cardiomyopathies are a group of mostly hereditary, rare heart diseases in which the structure of the heart muscle tissue is impaired.

29 Jul 2026

Daily multivitamin improves functional health in older adults, study finds

The ability to perform everyday activities free of debilitating symptoms profoundly affects quality of life as we age.

27 Jul 2026

Scientists link genetic spelling mistakes to sudden cardiac death

Scientists have found that the 'sudden' cardiac death condition related to high profile deaths or major medical episodes of sports stars including Fabrice Muamba, Christian Erikson and Mark-Vivian Foe has numerous linked gene variations, or "spelling mistakes", which highlights a potentially treatable vulnerability.

21 Jul 2026

NOX4 inhibition may protect hearts affected by Duchenne muscular dystrophy

Researchers at the University of South Florida USF Health Morsani College of Medicine have identified a potential pathway that could protect cardiac function in people with Duchenne muscular dystrophy, a progressive and fatal genetic disease that weakens the body's muscles.

17 Jul 2026

New molecular mechanism identified in common inherited heart disease

A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), working in collaboration with an international research team, has identified a new molecular mechanism involved in hypertrophic cardiomyopathy, the most common inherited cardiovascular disease.

7 Jul 2026

Vascular organoids may be an effective treatment for ischemic heart disease

Ischemic heart disease (IHD), also known as coronary artery disease, is a leading cause of death and morbidity in western countries. IHD arises when blood vessels of the heart become clogged, blunting oxygen and nutrient supply to heart muscle cells, which eventually die off, leading to heart attack or heart failure.

2 Jul 2026

Review links iron-dependent cell death to pathogenesis of Friedreich's Ataxia

Published in the open-access journal Ferroptosis and Oxidative Stress, the review by Giovanni Cravin and Giorgio Cozza from the University of Padua examines the growing evidence linking ferroptosis to the pathogenesis of Friedreich's Ataxia (FRDA), a rare inherited neurodegenerative disease characterized by progressive neurological decline, cardiomyopathy, and premature mortality.

30 Jun 2026

Three courageous heart transplant survivors are celebrated by the British Heart Foundation for giving their old hearts for research

The British Heart Foundation is celebrating three incredible young women who donated their old hearts to science after having heart transplant surgery.

25 Jun 2026

Recognizing perinatal heart failure early reduces life-threatening risks

Early detection and timely treatment of heart failure in pregnant or postpartum women are crucial to prevent serious complications, such as irregular heartbeat, stroke and death, according to a new American Heart Association scientific statement, "Heart Failure Occurring in the Perinatal Period."

25 Jun 2026

Scientists discover how fat tissue drives the spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is aggressive and hard to treat. But the role of fat tissue in how the cancer spreads may help point toward new understanding and treatments, according to a new paper from scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) and colleagues at Georgetown University's Lombardi Comprehensive Cancer Center.

23 Jun 2026

Novel gene therapy appears to be safe for Friedreich ataxia cardiomyopathy

A new gene therapy appears to be safe in patients diagnosed with Friedreich ataxia cardiomyopathy, a progressive and fatal inherited cardiac disease, according to a phase 1 clinical trial led by Weill Cornell Medicine researchers.

17 Jun 2026

Protein repair defects linked to hidden heart failure

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed in patients with idiopathic dilated cardiomyopathy (IDCM ).

9 Jun 2026

Diabetes drug dramatically lowers heart failure risk in genetic carriers

Rare genetic variants known to cause cardiomyopathy, an inherited cause of a weak heart, can increase the risk of patients developing heart failure.

8 Jun 2026

What pregnancy reveals about a woman’s future heart health

Pregnancy acts as a natural cardiovascular stress test, revealing hidden heart disease and identifying women at higher long-term risk after complications such as preeclampsia, gestational diabetes, and preterm birth. The review highlights major evidence gaps in cardio-obstetric care and calls for stronger postpartum screening, dedicated women’s health clinics, and better inclusion of reproductive-age women in research.

3 Jun 2026

RNA therapy targets genetic cause of heart failure in the Netherlands

Using patient-derived cardiac tissue and stem cell-based models, the team of translational researchers demonstrated that targeting the genetic cause of disease improved cellular abnormalities and identified the biological pathways involved.

29 May 2026

Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence

The review highlights nanocarriers, microspheres, hydrogels, microneedles, long-acting formulations, and co-formulations as promising but mostly early-stage strategies that still require stronger long-term clinical evidence.

27 May 2026

Scientists visualize a key cell protein regulating inflammatory disease pathways

University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part of newly published research from the College of Medicine.

22 May 2026

Pregnancy magnifies heart risk, but age alone does not explain why

A large U.S. cohort-crossover study found that pregnancy and the postpartum period were linked to about a seven-fold higher relative risk of major adverse cardiovascular events compared with patients’ nonpregnant baseline risk. This relative risk increase did not vary by maternal age, suggesting pregnancy broadly amplifies existing cardiovascular risk rather than making older age itself the driver of pregnancy-specific cardiovascular complications.

20 May 2026

New research maps the biological toll of drinking

A new review published in the journal Addiction confirms drinking causes substantial harm to health. Some of those harms may be reversible if the person reduces or stops drinking.

14 May 2026

New trial aims to improve ATTR-CM diagnosis in heart failure

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized yet frequently underdiagnosed cause of heart failure, particularly among older adults.

13 May 2026