Exosome News and Research

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Researchers discover a previously unknown genetic cause for microcephaly

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.

28 Oct 2025

RION engages Lonza to scale manufacturing exosome based therapeutics

RION, a commercial and clinical-stage regenerative medicine company pioneering platelet-derived exosomes for both human and animal health applications, has announced a collaboration with Lonza, one of the world’s largest contract development and manufacturing organizations (CDMOs), to provide cGMP manufacturing and technical support for commercial scale production of its Purified Exosome Product™ (PEP™) drug substance for late phase clinical supply and beyond.

From Lonza 26 Sep 2025

Exosomes carry key indicators of biological aging

A new research paper featured on the cover of Volume 17, Issue 8 of Aging (Aging-US) was published on July 30, 2025, titled "Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures."

2 Sep 2025

MicroRNA panels show promise for improving prostate cancer diagnosis

Prostate cancer is highly heterogeneous, ranging from slow-growing tumors to aggressive, life-threatening disease.

2 Sep 2025

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Traumatic injuries of the central nervous system (CNS)-such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)-are characterized by oxidative damage and neuroinflammation.

28 Aug 2025

New technique enables efficient loading of large biomolecules into exosomes

Exosomes, naturally derived vesicles responsible for intercellular communication, are emerging as next-generation drug delivery systems capable of transporting therapeutics to specific cells.

13 Aug 2025

Exosomes play a dual role in cancer progression and immune regulation

Tiny extracellular vesicles known as exosomes are emerging as key regulators of the tumor microenvironment (TME), influencing how cancer progresses, spreads, and responds to treatment.

7 Aug 2025

New method uses exosome stiffness for lung cancer gene detection

The research team led by Senior Researchers Yoonhee Lee from the Division of Biomedical Technology and Gyogwon Koo from the Division of Intelligent Robot at DGIST (under President Kunwoo Lee) has developed a technology that distinguishes lung cancer gene mutations solely by measuring the "stiffness" of exosomes-tiny particles released from cancer cells in the bloodstream-using atomic force microscopy (AFM).

30 Jul 2025

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

This new article publication from Acta Pharmaceutica Sinica B, discusses the use of engineered platelet-derived exosomal spheres for enhanced tumor penetration and extended circulation in melanoma immunotherapy.

12 Jul 2025

TTUHSC researchers seek to understand TBX2's role in bone metastasis of prostate cancer

The American Cancer Society estimates that more than 313,780 cases of prostate cancer will be diagnosed in the United States in 2025, resulting in approximately 35,770 deaths.

12 Jun 2025

Mitochondrial transplantation as a strategy to address metabolic decline in aging

Announcing a new publication for Acta Materia Medica journal. Aging impairs adipose tissue function and contributes to metabolic disorders, such as obesity and insulin resistance.

10 May 2025

MD Anderson researchers present promising clinical trial results at AACR 2025

Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025.

26 Apr 2025

Liquid biopsy offers new hope for early cancer detection

Cancer is one of the leading causes of death globally, with nearly 20 million new cases and 9.7 million deaths in 2022.

22 Apr 2025

Study reveals a potential breakthrough in treating osteonecrosis of the femoral head

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

15 Apr 2025

Exosome-mediated siRNA delivery targets antibiotic resistance in bacteria

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial infections by silencing their resistance genes.

7 Mar 2025

Strontium-enhanced exosomes show promise for osteoarthritis treatment

Temporomandibular joint osteoarthritis (TMJOA) is a debilitating condition that causes severe joint pain, restricted mobility, and progressive cartilage degradation.

24 Feb 2025

Researchers launch startup to revolutionize targeted drug delivery using milk exosomes

Two Nebraska researchers have launched a startup company aimed at bringing to market an innovative method for delivering therapeutics, gene editing tools, plasmids and more to targeted locations in the human body.

17 Jan 2025

Investigating the impact of CircRNAs on cancer progression and drug resistance

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance.

6 Jan 2025

Harnessing exosomes to deliver therapeutic proteins

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

11 Dec 2024

Exosomes: A double-edged sword in hepatocellular carcinoma

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune surveillance.