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Study examines the relationship between leukocyte telomere length and age-related cataract

Cataracts remain the leading cause of blindness worldwide among adults over 50, despite major advances in surgical treatment.

12 Feb 2026

Specific foods linked to autism risk via immune pathways

Genetic and clinical data suggest dietary factors may influence autism risk via immune pathways, highlighting the need for further research in this area.

14 Jan 2026

Novel cryo-EM findings could revolutionize T cell immunotherapy design

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full understanding of how they actually work has eluded researchers.

16 Dec 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Blood group A linked to a higher risk of primary biliary cholangitis

Findings indicate blood group A elevates the risk of primary biliary cholangitis, suggesting ABO group analysis could aid in autoimmune liver disease diagnosis.

19 Nov 2025

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with a five-year survival rate near 50%.

13 Nov 2025

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

Scientists uncover why many cancer patients develop chemotherapy-induced neuropathy

Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why many cancer patients develop nerve damage after chemotherapy.

30 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Targeting the glycocalyx may offer a new approach to reduce frailty in older adults

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 30, 2025, titled, "Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity."

14 Oct 2025

Elderberry juice boosts key genes for metabolic flexibility in overweight adults

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight adults during meal challenges.

3 Oct 2025

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung and prostate cancer.

26 Sep 2025

Study shows dementia patients exposed to pollution had longer telomeres

Researchers studying a Swedish aging cohort found no overall link between air pollution and telomere shortening, a key marker of biological aging. Intriguingly, dementia patients exposed to higher pollution showed longer telomeres, though results were statistically non-significant.

24 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

Oral drug baricitinib shows promise in slowing early type 1 diabetes progression

In 2023, the groundbreaking Australian BANDIT (Baricitinib in New Onset Type 1 Diabetes) trial [1] reported that a daily pill of baricitinib, commonly prescribed for rheumatoid arthritis and alopecia, could safely preserve the body's own insulin production and slow the progression of type 1 diabetes (T1D) in people recently diagnosed with the condition.

19 Sep 2025

Study reveals how centenarians preserve youthful immune defenses

Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.

15 Sep 2025

Targeting complement with an inhibitor may prevent preterm birth and protect the baby’s brain

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that contribute to fetal brain inflammation and preterm birth, the latter of which is the leading cause of complications and death in newborns.

4 Sep 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025

Blocking a single gene disrupts vitamin D metabolism and cancer pathways in new cell study

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells. Disruption of this enzyme altered cancer-related pathways and cell viability, highlighting its potential as a therapeutic target.

21 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025