Compound News and Research

RSS

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

31 Oct 2025

Researchers visualize how brain network development is altered in rare childhood disorder

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder.

31 Oct 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

At the hollow in Florida, the ‘medical freedom’ movement finds its base camp

MAGA and MAHA are happily married in Florida, and nowhere more at home than in Sarasota County, where on a humid October night a crowd of several hundred gathered to honor state Surgeon General Joseph Ladapo, his wife, and an unlicensed Canadian radiologist who treats cancer with horse paste.

31 Oct 2025

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and the Eötvös Loránd University in Budapest has developed a groundbreaking new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies.

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages.

30 Oct 2025

Breakthrough could offer a new therapeutic option for stopping diabetes-induced complications

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

30 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

New imaging technique maps medication distribution across skin layers

A new study by the Hebrew University has developed a rapid imaging method that reveals how drugs move through the skin, in just ten minutes.

29 Oct 2025

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes.

29 Oct 2025

Flavanol-rich foods offer vascular protection during extended sitting

New research from the University of Birmingham shows that eating flavanol-rich foods-like tea, berries, apples, and cocoa-can protect vascular health in men from the harmful effects of prolonged sitting.

29 Oct 2025

Hydroxytyrosol from olives shows new promise as a brain-protective compound

This review highlights hydroxytyrosol's role as a neuroprotective agent, activating key pathways for mental and vascular health through olive-derived compounds.

29 Oct 2025

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.

28 Oct 2025

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain's sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need.

27 Oct 2025

Researchers reveal how maternal stress reshapes fetal growth and brain development

Maternal stress, encompassing physical, emotional, and psychological distress, remains a widespread yet underestimated risk during pregnancy.

24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

Toxic compounds from heated e-cigarette fluids can damage lung cells

A study by University of California, Riverside, scientists has found that two toxic chemicals can form when the main ingredient in most e-cigarette fluids is heated, and that these compounds can harm human lung cells.

23 Oct 2025

Discovery could pave the way for new generation of RNA-based cancer treatments

Researchers fhave created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive.

23 Oct 2025

Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

Enamine, a leading chemistry and R&D services company, today announced that it was a key synthetic chemistry contributor to a first-of-its-kind, open-science approach that led to the development of a promising broad-spectrum coronavirus antiviral pre-clinical candidate.

23 Oct 2025

A new way to monitor chemotherapy drug behavior inside cells

Scientists have made incredible progress in developing cancer therapies that help patients across cancer types.

22 Oct 2025

Compound News and Research

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Researchers visualize how brain network development is altered in rare childhood disorder

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

At the hollow in Florida, the ‘medical freedom’ movement finds its base camp

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Breakthrough could offer a new therapeutic option for stopping diabetes-induced complications

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

New imaging technique maps medication distribution across skin layers

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

Flavanol-rich foods offer vascular protection during extended sitting

Hydroxytyrosol from olives shows new promise as a brain-protective compound

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

Researchers reveal how maternal stress reshapes fetal growth and brain development

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

Toxic compounds from heated e-cigarette fluids can damage lung cells

Discovery could pave the way for new generation of RNA-based cancer treatments

Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

A new way to monitor chemotherapy drug behavior inside cells

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News