Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Sugary beverages contribute to millions of diabetes and heart disease cases

A new study from researchers at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University, which published in Nature Medicine on January 6, estimates that 2.2 million new cases of type 2 diabetes and 1.2 million new cases of cardiovascular disease occur each year globally due to consumption of sugar-sweetened beverages.

6 Jan 2025

Social connections may boost immunity and reduce disease risk

Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests.

3 Jan 2025

Lithocholic acid enhances health and lifespan, mimicking calorie restriction

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose tolerance, and lifespan in aged organisms.

1 Jan 2025

Insulin degradation uncovered as a new driver of resistance

Researchers reveal insulin resistance may be driven by insulin degradation during transit in the bloodstream, challenging the belief that cell defects are the primary cause.

22 Dec 2024

Annona squamosa extracts show promise in treating pain and arthritis

In Brazil, researchers have identified substances with analgesic, anti-inflammatory, anti-hyperalgesic (against persistent pain) and anti-arthritic activity in the leaves of Annona squamosa, a tree popularly known in the country as fruta-do-conde or pinha.

20 Dec 2024

The role of phytochemicals in combating metabolic diseases

This editorial reviews the impact of phytochemicals on metabolic diseases, emphasizing their potential in reducing inflammation and improving health outcomes.

19 Dec 2024

New study identifies potential target for treating diabetic cardiomyopathy

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders.

12 Dec 2024

Scientists identify potential therapeutic targets for diabetic kidney disease

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

10 Dec 2024

Sweet news: Dark chocolate reduces type 2 diabetes risk

Findings show dark chocolate may lower type 2 diabetes risk, while milk chocolate contributes to weight gain. Implications for dietary choices discussed.

10 Dec 2024

Eating breakfast later lowers blood sugar spikes in type 2 diabetes patients

Skipping early breakfasts may reduce blood sugar spikes in people with type 2 diabetes, with later breakfast timings showing significant benefits.

10 Dec 2024

Can HIIT's metabolic benefits last? New study explores post-exercise sustainability in diabetes

Researchers investigate whether high-intensity interval training-induced metabolic benefits sustain or differ after prolonged training cessation.

9 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

Researchers develop diabetes prediction system using clinical and genetic data

A research team led by professor Nan-Hee Kim from Korea University's College of Medicine (Nan-Hee Kim and So-Young Park of Department of Endocrinology and Metabolism; Min-Hee Kim and Jae-Young Kim of Health Science Research Center) recently developed a diabetes prediction system using clinical and genetic data. The system was registered for the domestic patent.

5 Dec 2024

Replacing carbohydrates with protein and fat improves cholesterol profiles in type 2 diabetes

Research indicates that a carbohydrate-reduced, high-protein diet improves lipid metabolism and reduces liver fat in type 2 diabetes without weight loss.

5 Dec 2024

How carrageenan affects insulin resistance

A randomized controlled trial found that carrageenan, a common food additive, may cause subclinical inflammation and insulin resistance in overweight individuals, mediated by gut permeability and inflammation. Effects were linked to BMI but not observed in non-overweight participants during short-term exposure.

3 Dec 2024

Gut microbes may have helped human ancestors develop larger brains

Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance.

3 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024

Visceral fat found to contribute to Alzheimer's disease development

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

2 Dec 2024

Can beef fit in a heart-healthy diet? Review provides new insights

A systematic review suggests unprocessed beef has minimal impact on cardiovascular health markers.

1 Dec 2024

Heart health benefits soar with regular sleep schedules, research finds

Irregular sleep patterns significantly increase the risk of major adverse cardiovascular events (MACE), with higher sleep regularity associated with reduced cardiovascular risks. This large UK Biobank study underscores the need to prioritize sleep regularity in public health and clinical guidelines.

1 Dec 2024