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Wayne State researchers pursue new treatments for ocular chemical injuries in military personnel

Researchers at Wayne State University are pursuing new therapies for treating chemical injuries to the eyes with the help of a two-year, $400,400 grant from the U.S. Department of Defense (DOD).

28 Aug 2025

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

Can the gut microbiome adapt to protect the brain after stroke?

Alterations in gut microbiota post-stroke may drive metabolic changes, presenting opportunities for innovative therapeutic strategies in acute stroke recovery.

28 Aug 2025

New trial will test if a low-plastic lifestyle improves your health

A new protocol published in BMJ Open outlines the PERTH trial, a randomized controlled study testing whether a four-week low-plastic lifestyle can reduce exposure to plastic-derived endocrine-disrupting chemicals.

27 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

Researchers discover why smoking tobacco helps people with ulcerative colitis

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.

25 Aug 2025

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk.

25 Aug 2025

Why a common pesticide may alter brain growth in school-age children

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25 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

AI predicts designer drug structures for improved detection

How does one identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement. The chemical structure variations that help these compounds avoid detection also make them unpredictable in the body - a quality that poses serious health consequences.

21 Aug 2025

Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025