Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Protein made by stressed cancer cells helps tumors to evade immune attack

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows.

18 Feb 2026

Developmental ANGPTL4 deficiency protects mice from colitis and tumors

A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation.

18 Feb 2026

Scientists uncover nanoplastics in brain tissue and question their role in neurological disease

Emerging evidence suggests nanoplastics accumulate in human tissues including the brain and may contribute to neuroinflammation and neurodegenerative disease pathways. However, causality, exposure routes, and long-term health effects remain uncertain and require coordinated research.

17 Feb 2026

AI tool can accurately predict colorectal cancer risk in UC-LGD patients

People with ulcerative colitis (UC), a chronic inflammatory bowel disease, are up to four times more likely to develop colorectal cancer than the general population.

17 Feb 2026

NCCN publishes new guidelines for management of pediatric soft tissue sarcomas

The National Comprehensive Cancer Network (NCCN) today published new NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Soft Tissue Sarcomas.

17 Feb 2026

Dysplasia grade predicts colorectal cancer risk in people with IBD

People with inflammatory bowel disease (IBD) and precancerous colorectal lesions are much more likely to develop colorectal cancer, a new study shows.

16 Feb 2026

Synergistic drug pair shows promise for spinal cord injury recovery

Spinal cord injury remains one of the most challenging neurological conditions to treat, largely because damage continues to worsen long after the initial trauma.

16 Feb 2026

Advanced use of MRI aids in accurate identification of rare, atypical parkinsonian disorders

An international study led by researchers from the Sant Pau Research Institute (IR Sant Pau) shows that advanced use of magnetic resonance imaging (MRI) allows much more accurate identification of patients with progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD).

16 Feb 2026

Osteoprotegerin links bone metabolism to cardiovascular disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Osteoprotegerin (OPG), a glycoprotein in the tumor necrosis factor superfamily, regulates bone metabolism by suppressing the formation and activation of osteoclasts.

13 Feb 2026

Early cognitive stimulation preserves memory in Alzheimer’s

A team from the Institute of Neurosciences of the University of Barcelona (UBneuro) has discovered that early and sustained cognitive stimulation can help preserve brain connectivity and memory in Alzheimer's disease, even in advanced stages of the pathology.

12 Feb 2026

FDA-approved anti-seizure drug could help fight Alzheimer's disease

While physicians and scientists have long known Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced.

12 Feb 2026

Leica Biosystems revolutionizes histology workflows with global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System

Leica Biosystems, a Danaher company and a global leader in anatomic pathology solutions, is redefining histology workflows with the global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System.

From Leica Biosystems 12 Feb 2026

New roadmap integrates aging into Parkinson disease models

Even though aging is the largest risk factor for Parkinson's disease, the majority of research aimed at taming the able neurodegenerativeincur motor disease has largely left aging out of the mix.

11 Feb 2026

Study uncovers immune trigger behind vaccine-induced immune thrombocytopenia and thrombosis

A global research collaboration of scientists from McMaster University (Canada), Flinders University (Australia) and Universitätsmedizin Greifswald (Germany) uncovered why a small number of people developed dangerous blood clots after either receiving certain COVID‑19 vaccines or experiencing a natural adenovirus infection, and the answer lies in an unexpected case of misdirected targeting by the immune system.

11 Feb 2026

Advanced three-dimensional imaging maps vascular amyloid spread

Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy (CAA).

11 Feb 2026

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Researchers engineered CD4+ chimeric antigen receptor T cells targeting fibrillar amyloid beta and tested them in a mouse Alzheimer model. The preclinical study showed reduced amyloid pathology and altered neuroimmune responses, supporting CAR-T immunotherapy as a potential future Alzheimer strategy.

11 Feb 2026

Transcription factor HOXD13 drives melanoma growth and immune evasion

A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors' ability to evade attack by the body's immune system, a new study shows.

11 Feb 2026

New guidance for the diagnosis and management of inherited hyperbilirubinemia

Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting bilirubin metabolism and transport.

10 Feb 2026

Study reveals how inherited genetic abnormalities raise Barrett’s esophagus risk

Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett's esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, one of the fastest-spreading and deadliest forms of cancer.

10 Feb 2026

Preexisting flu immunity may offer baseline protection against avian influenza

Are seasonal flu antibodies also effective against avian flu? A team from the University of Geneva (UNIGE) has shown that a specific type of antibody associated with the former virus—already present throughout the population—may offer baseline protection against the latter.

10 Feb 2026