Proliferation News and Research

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Galectin-3 identified as key driver of chemoresistance in pancreatic cancer

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality.

17 Jul 2025

New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

WEE1 identified as a key driver of immune resistance in cancer

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues.

15 Jul 2025

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems.

14 Jul 2025

Researchers develop novel engineered extracellular matrix to improve cartilage repair

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to address the challenge of cartilage repair.

11 Jul 2025

Does soup really work when you’re down with cold or flu?

A systematic review found that chicken-based and vegetable-enriched soups may modestly reduce the severity and duration of acute respiratory tract infections. However, stronger evidence is needed before soup can be recommended as a clinical treatment.

10 Jul 2025

How does olive oil affect gut health?

Could olive oil’s hidden compounds be the key to a healthier gut? New research uncovers how olive-derived bioactives transform our microbiome and may unlock future therapies for digestive and metabolic health.

9 Jul 2025

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion.

9 Jul 2025

Retinal organoid model advances understanding of dry age-related macular degeneration

Age-related macular degeneration (AMD), classified into dry and wet types, poses a significant threat to the vision of the elderly population globally.

9 Jul 2025

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor progression and dampening immune responses.

7 Jul 2025

Flavonoid diversity, not just quantity, drives better health outcomes

This study reveals that diverse flavonoid intake is crucial for lowering chronic disease risk and mortality, advocating for a varied diet rich in flavonoids.

7 Jul 2025

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth.

7 Jul 2025

XPR1 silencing enhances immune response and reduces ovarian tumor growth

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression.

4 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

NAD+ supplementation could be a potential treatment for accelerated aging diseases

Can research into a rare, accelerated aging disease and "zombie cells" teach us something about the normal aging process?

4 Jul 2025

Study unveils powerful strategy to rejuvenate effectiveness of CAR T cell therapy against glioblastoma

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors.

3 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Study enhances the understanding of urolithiasis pathogenesis

A recent study published in Genes & Diseases reveals new insights into the relationship between immune cell characteristics, blood metabolites, and the risk of urolithiasis.

2 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Breakthrough study reveals killing power of CD4 T cells against cancer

In the fight against cancer, immunotherapy - which aims to boost the body's natural defences against cancer - is experiencing remarkable growth. Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells.

1 Jul 2025

Proliferation News and Research

Galectin-3 identified as key driver of chemoresistance in pancreatic cancer

New monoclonal antibody enhances immune response by selectively targeting Tregs

WEE1 identified as a key driver of immune resistance in cancer

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

Researchers develop novel engineered extracellular matrix to improve cartilage repair

Does soup really work when you’re down with cold or flu?

How does olive oil affect gut health?

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Retinal organoid model advances understanding of dry age-related macular degeneration

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity

Flavonoid diversity, not just quantity, drives better health outcomes

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

XPR1 silencing enhances immune response and reduces ovarian tumor growth

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

NAD+ supplementation could be a potential treatment for accelerated aging diseases

Study unveils powerful strategy to rejuvenate effectiveness of CAR T cell therapy against glioblastoma

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

Study enhances the understanding of urolithiasis pathogenesis

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Breakthrough study reveals killing power of CD4 T cells against cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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