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Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

Discovery of fat-regulating enzyme points to a new obesity therapy

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD).

23 Dec 2025

Artificial intelligence improves risk stratification in oropharyngeal cancer

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment.

23 Dec 2025

Older age affects functional recovery after spinal cord injury

A new study published on December 23, 2025, in Neurology, the medical journal of the American Academy of Neurology, looks at how age may affect recovery for people with spinal cord injuries.

23 Dec 2025

Paternal microplastic exposure alters metabolic health in offspring

A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father's exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring.

23 Dec 2025

Study validates OVCAR3 as a model for high-grade serous ovarian cancer

A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled "Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53."

23 Dec 2025

$Neighborhood disadvantage shapes recovery after hip fracture$

Neighborhood disadvantage shapes recovery after hip fracture

Older adults who live in economically disadvantaged neighborhoods spend significantly fewer days at home in the year after a fall-related hip fracture than those living in more affluent areas, according to a large national study published today in JAMA Network Open.

23 Dec 2025

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Antimicrobial resistance emerges as a slow-moving global pandemic

Once a medical miracle, antibiotics are now losing their power. Across the world, common infections are becoming harder-and sometimes impossible-to treat.

23 Dec 2025

Robots and click chemistry open a new frontier in antibiotic discovery

Researchers have used a cutting-edge robotic system capable of synthesizing hundreds of metal complexes to develop a possible antibiotic candidate - offering fresh hope in the global fight against drug-resistant infections.

23 Dec 2025

Marijuana use associated with worse school performance and emotional distress for teens

Using marijuana just once or twice a month was associated with worse school performance and emotional distress for teens, according to a large national study of adolescents led by Ryan Sultán, an assistant professor of clinical psychiatry at Columbia University Vagelos College of Physicians and Surgeons.

23 Dec 2025

An Arm and a Leg: A few more good things from 2025

An Arm and a Leg host Dan Weissmann breaks down how two states passed laws aimed at protecting people from things like medical debt, insurance delays and denials, and corporate profiteering.

23 Dec 2025

Medical bills can be vexing and perplexing. Here’s this year’s best advice for patients.

A Texas boy's second dose of the MMRV vaccine cost over $1,400. A Pennsylvania woman's long-acting birth control cost more than $14,000.

23 Dec 2025

After outpatient cosmetic surgery, they wound up in the hospital or alone at a recovery house

Lisa Farris worried that a nasty infection from recent liposuction and a tummy tuck was rapidly getting worse. So she phoned the cosmetic surgery center to ask if she should head to the emergency room, she alleges in a lawsuit.

23 Dec 2025

Second WHO Global Summit on Traditional Medicine marks a major milestone for global health

The second WHO Global Summit on Traditional Medicine, jointly organized with the Government of India, concluded today in New Delhi, marking a major milestone for global health as it drew over 16 000 online registrations and brought together 800 delegates from more than 100 countries, including ministers from over 20 nations.

23 Dec 2025

THC products provide small improvements in pain but carry side effects

A new systematic evidence review finds that cannabis products that carry relatively high levels of the psychoactive compound tetrahydrocannabinol, commonly known as THC, may provide short-term improvements in pain and function.

22 Dec 2025

Early brain connectivity predicts recovery after traumatic brain injury

After traumatic brain injury (TBI), some patients may recover completely, while others retain severe disabilities.

22 Dec 2025

Researchers create the most detailed 3D maps of the human genome

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome's three‑dimensional organization across time and space, according to a new study published in Nature.

22 Dec 2025

Reframing the role of MCL1 in cancer signaling and metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology.

22 Dec 2025