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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Both low and moderate-high intensity exercise could help fight against Alzheimer's

Researchers at University of California San Diego and Wake Forest University have found that both low and moderate-high intensity exercise could be valuable tools in the fight against Alzheimer's.

24 Apr 2025

AI predicts pediatric glioma recurrence using multiple brain scans

Artificial intelligence (AI) shows tremendous promise for analyzing vast medical imaging datasets and identifying patterns that may be missed by human observers.

24 Apr 2025

Epilepsy after brain injury increases risk of premature death

People who develop epilepsy after a traumatic brain injury are at an 80 percent higher risk of premature death compared to those who have suffered a similar brain injury without developing epilepsy.

24 Apr 2025

NIH study reveals how inflammation affects pain perception

Researchers uncover the cellular and molecular basis for sensing heat and inflammatory pain.

24 Apr 2025

Step-and-shoot proton arc therapy reduces cancer treatment side effects

For many cancer patients, side effects from radiation can be debilitating. But a new way of delivering radiation treatment has proven effective at eliminating a hard-to-treat cancer with the only side effect being light skin discoloration, even nine months after treatment.

24 Apr 2025

Metabolic driver of Parkinson’s offers new target for treatment

Researchers have identified a key enzyme driving forms of Parkinson’s, and have shown how blocking it restores normal function in animal and cell models – offering a promising new drug target for the condition.

24 Apr 2025

Metabolic syndrome in midlife linked to higher dementia risk

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published on April 23, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

23 Apr 2025

Scientists unlock secrets of how cells navigate the body

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science framework to better understand how cells travel through the body.

23 Apr 2025

New approach may prevent neurotoxic protein aggregates in ALS

Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

23 Apr 2025

Move more, think sharper: How physical activity boosts brain health in aging

A brisk walk, a splash of water aerobics, or even a light jog around the block – if your heart rate goes up then so too will your brain health according to new research from the University of South Australia.

23 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

Genetic susceptibility to schizophrenia associated with thinner retinas

A new study led by the University of Zurich has shown that evidence of genetic susceptibility to schizophrenia can be found in the retina. This finding could help improve the early detection of the disorder.

22 Apr 2025

Carotid artery plaque contains elevated micronanoplastics

People with plaque in the blood vessels of their neck have a higher amount of tiny plastic particles in those vessels compared to people with healthy arteries.

22 Apr 2025

UCLA launches trial of wearable ADHD therapy for children exposed to alcohol in the womb

Researchers at UCLA Health are launching the first clinical trial to test whether a wearable device that delivers gentle nerve stimulation during sleep could ease ADHD symptoms in children with prenatal alcohol exposure.

22 Apr 2025

Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

Single psychedelic dose boosts long-term cognitive flexibility in mice

University of Michigan researchers have found that certain psychedelic compounds improve the brain’s ability to adapt and flexibly learn new concepts over long periods.

22 Apr 2025

Study uncovers how prenatal stress leaves a molecular imprint on babies

A new study has uncovered how stress experienced by mothers during pregnancy leaves a molecular imprint on their babies—starting before birth.

22 Apr 2025

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Age and sex shape Alzheimer’s blood biomarkers, study finds

ESTHER study found that non-modifiable factors like age, sex, and APOE ε4 status significantly influence blood biomarker levels linked to Alzheimer’s disease. GFAP and NfL levels, in particular, showed strong age- and sex-related patterns, with GFAP levels rising faster in women.

22 Apr 2025

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity-two issues that commonly co-occur with alcohol use disorder (AUD).

22 Apr 2025