Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

High BMI linked to vascular dementia risk

High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular + unspecified dementia), according to new research from the University of Bristol and University Hospital of Copenhagen (Rigshospitalet and Herlev-Gentofte hospital).

22 Jan 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Rhythmic carbon dioxide exposure may enhance brain waste clearance mechanisms

Abnormal clumps of proteins like α-synuclein, amyloid beta and tau are associated with neurodegenerative conditions like Parkinson's and Alzheimer's disease, but a waste removal mechanism called the glymphatic pathway can clear these proteins and other metabolic byproducts from the brain.

20 Jan 2026

Elevated tau in Long COVID patients raises risk for neurodegenerative diseases

A study of 227 individuals who experienced neuro cognitive difficulties post COVID-19 infection – such as headaches, vertigo, balance dysregulation, changes in taste/smell, and brain fog – displayed a significant increase in their blood plasma of a crucial protein called tau, which is found in nerves and especially in the brain.

19 Jan 2026

Super agers' resilience against Alzheimer's disease linked to protective gene variant

The gene variant posing the greatest genetic risk of late-onset Alzheimer's disease (AD) is called APOE-ε4. A different variant of the same gene, APOE-ε2, is thought to confer protection against AD.

19 Jan 2026

Study reveals how ketogenic diet protects against epilepsy seizures

University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy seizures and possibly neurodegenerative diseases such as Alzheimer's and Parkinson's.

16 Jan 2026

Autonomous AI system screens for cognitive impairment using routine clinical notes

A team of Mass General Brigham researchers has developed one of the first fully autonomous artificial intelligence (AI) systems capable of screening for cognitive impairment using routine clinical documentation.

15 Jan 2026

Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia

Sickle cell anemia is the world's most common genetic disorder. It causes the red blood pigment hemoglobin to crystallize, which results in rigid, malformed red blood cells with a sickle shape.

15 Jan 2026

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.

14 Jan 2026

New European initiative aims to transform real world Alzheimer’s disease care

Today, the ACCESS-AD consortium is announcing the launch of a transformative European initiative that will accelerate the implementation of scientific innovations for Alzheimer's disease (AD) management in real-world health systems.

13 Jan 2026

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer's disease.

13 Jan 2026

Sex-based differences and role of BMP signaling in neurogenesis in Alzheimer's mice models

Alzheimer's disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows sex-based differences, with women being more at risk. However, the origin of these differences remains unknown.

9 Jan 2026

APOE gene: A major driver in Alzheimer's disease

Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.

9 Jan 2026

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest.

6 Jan 2026

Finger-prick blood test shows promise for detecting Alzheimer’s disease biology

Finger-prick dried blood sampling can accurately measure key Alzheimer’s disease biomarkers, including p-tau217, GFAP, and NfL, showing strong concordance with venous plasma and meaningful associations with CSF pathology. While analytical limitations remain, this minimally invasive approach shows promise as a scalable research and screening tool within biomarker-based diagnostic pathways.

6 Jan 2026

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two isoforms of a critical cellular energy sensor play distinct, and sometimes opposing, roles in Alzheimer's disease.

6 Jan 2026

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

A groundbreaking international study has demonstrated that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.

5 Jan 2026

New guidelines aim to standardize diagnosis of canine dementia

An international working group of canine cognition experts has released a set of guidelines for veterinarians to use in diagnosing and monitoring canine cognitive dysfunction syndrome (CCDS), or canine dementia.

5 Jan 2026

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Alzheimer's Disease News and Research

Further Reading

High BMI linked to vascular dementia risk

Unfolding the role of Hsp70 chaperones in neurodegeneration

Rhythmic carbon dioxide exposure may enhance brain waste clearance mechanisms

Elevated tau in Long COVID patients raises risk for neurodegenerative diseases

Super agers' resilience against Alzheimer's disease linked to protective gene variant

Study reveals how ketogenic diet protects against epilepsy seizures

Autonomous AI system screens for cognitive impairment using routine clinical notes

Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

New European initiative aims to transform real world Alzheimer’s disease care

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

Sex-based differences and role of BMP signaling in neurogenesis in Alzheimer's mice models

APOE gene: A major driver in Alzheimer's disease

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Finger-prick blood test shows promise for detecting Alzheimer’s disease biology

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

New guidelines aim to standardize diagnosis of canine dementia

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

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