Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Epstein family support accelerates USC’s mission to end Alzheimer’s

The USC Alzheimer's Therapeutic Research Institute will be renamed the USC Epstein Family Alzheimer's Therapeutic Research Institute in honor of Life Trustee Daniel J. Epstein '62, his wife Phyllis and their family, who have been the philanthropic leaders behind the university's world-leading efforts to make Alzheimer's a memory.

1 Dec 2025

Understanding tea's health benefits and risks

The review confirms that tea, particularly green tea, plays a crucial role in preventing cardiovascular diseases (CVDs), obesity, diabetes, and certain types of cancer.

1 Dec 2025

Southeast Asia's first consortium launched to tackle dementia

Nanyang Technological University, Singapore (NTU Singapore) is leading 24 clinicians from the region and beyond to set up Southeast Asia's first consortium dedicated to tackling dementia.

28 Nov 2025

New AI models detect dementia with high accuracy using EEG signals

Researchers at örebro University have developed two new AI models that can analyze the brain's electrical activity and accurately distinguish between healthy individuals and patients with dementia, including Alzheimer's disease.

27 Nov 2025

Driving behavior data may help detect early cognitive decline

Using in-vehicle driving data may be a new way to identify people who are at risk of cognitive decline, according to a study published on November 26, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Nov 2025

Shared genetic roots between delirium and Alzheimer’s disease

This study reveals genetic and proteomic risk factors for delirium, offering insights into its etiology and potential biomarkers for prediction and prevention.

26 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.

25 Nov 2025

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline.

25 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Arginine reduced amyloid beta aggregation in vitro and in both Drosophila and AppNL-G-F mouse models of Alzheimer’s disease, leading to fewer dense-core plaques and improved behavior. The study provides preclinical evidence that oral arginine may modulate amyloid pathology, although high dosing requirements and model limitations constrain human translation.

24 Nov 2025

New discovery could reshape how scientists think about Alzheimer’s treatment

Rutgers neuroscientist Peng Jiang was visiting his hometown of Qianshan, a city in China's Anhui province, when a neighbor came to his parents' house with a story that would stay with him.

24 Nov 2025

Oral arginine reduces amyloid buildup in Alzheimer’s models

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their clinical effectiveness remains limited.

21 Nov 2025

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function.

21 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

Study reveals how aging reshapes protein chemistry in the brain

A study by the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging.

20 Nov 2025

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective disease-modifying therapies remain elusive, underscoring the urgent need for novel neuroprotective strategies.

19 Nov 2025

Clogged brain drains may signal early Alzheimer's risk

"Drains" in the brain, responsible for clearing toxic waste in the organ, tend to get clogged up in people who show signs of developing Alzheimer's disease, a study by researchers from Nanyang Technological University, Singapore (NTU Singapore) has discovered.

19 Nov 2025

Alzheimer's Disease News and Research

Further Reading

Epstein family support accelerates USC’s mission to end Alzheimer’s

Understanding tea's health benefits and risks

Southeast Asia's first consortium launched to tackle dementia

New AI models detect dementia with high accuracy using EEG signals

Driving behavior data may help detect early cognitive decline

Shared genetic roots between delirium and Alzheimer’s disease

Obesity-related metabolic stress may affect brain health far earlier than expected

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Infection-related hospital stays linked to higher risk of developing dementia

Scientists uncover how brain enzyme OTULIN controls tau expression

New analysis shows one in two people in the U.S. live with neurological conditions

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

New discovery could reshape how scientists think about Alzheimer’s treatment

Oral arginine reduces amyloid buildup in Alzheimer’s models

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s

Changes in brain fats play a key role in Alzheimer's development and progression

Study reveals how aging reshapes protein chemistry in the brain

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Clogged brain drains may signal early Alzheimer's risk

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