Genomic News and Research

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New platform could help advance genomic medicine research, drug discovery

A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published recently in Genome Biology.

8 Feb 2021

CRISPR genomic editing to obtain more productive and nutritive plant varieties

New study by the IBMCP of the UPV university facilitates the use of the CRISPR genomic editing technique on plants.

8 Feb 2021

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Why the U.S. is underestimating Covid reinfection

Kaitlyn Romoser first caught Covid-19 in March, likely on a trip to Denmark and Sweden, just as the scope of the pandemic was becoming clear. Romoser, who is 23 and a laboratory researcher in College Station, Texas, tested positive and had a few days of mild, coldlike symptoms.

8 Feb 2021

COVID-19 pandemic and nanotechnology

Writing in the International Journal of Nanomedicine, Professor Dongki Yang, from the Department of Physiology, Gachon University, South Korea, has reviewed the available knowledge on the coronaviruses, current approaches to tackle the newly emerged SARS-CoV-2 infection, and the innovative application of nanotechnology in the COVID-19 pandemic.

8 Feb 2021

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized.

8 Feb 2021

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv preprint server.

7 Feb 2021

Study shows how bacteriophage lysis genes could be key to developing new antibiotics

A study from the Center for Phage Technology, part of Texas A&M's College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the "hidden" genes in bacteriophages -- types of viruses that infect and destroy bacteria -- may be key to the development of a new class of antibiotics for human health.

7 Feb 2021

Researchers develop systems to detect an atypical fungus responsible for severe pneumonia

The group led by Dr. Enrique J. Calderón - "Clinical Epidemiology and Vascular Risk" at the Institute of Biomedicine of Seville - IBiS/University Hospitals Virgen del Rocío and Macarena/CSIC/University of Seville, also a member of CIBERESP, participated in a project with researchers from CIBER-BBN, in which they developed systems to detect Pneumocystis jirovecii, an atypical fungus responsible for very severe pneumonia in immunosuppressed patients.

6 Feb 2021

European Union funds new project to improve personalized treatments for ovarian cancer

The European Union has funded a project to improve personalized treatments for ovarian cancer with nearly 15 million euros for five years. The international DECIDER project has partners from 14 organizations in seven EU countries.

5 Feb 2021

Researchers to create computational models to improve treatments for ovarian cancer

The 5-year research project involves 14 organizations in seven EU countries and is funded by €15 M from the EU.

4 Feb 2021

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Scripps Research, a globally recognized nonprofit biomedical research institute, today announced a collaborative research program with Tempus, a leader in precision medicine and artificial intelligence, to develop a predictive model of glucose responses in people with and without type 2 diabetes.

4 Feb 2021

Scientists identify genomic signatures of long-term survival in luminal breast cancer patients

Researchers at NUI Galway have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival.

4 Feb 2021

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Like weeds sprouting from cracks in the pavement, cancer often forms in sites of tissue damage. That damage could be an infection, a physical wound, or some type of inflammation.

4 Feb 2021

Genomic study suggests SARS-CoV-2 clade 20C was imported into Japan from the US

A new study describes the outcome of such sequencing efforts in Japan as an important tool towards containing the spread of the infection.

3 Feb 2021

Researchers develop new modeling to map SARS-CoV-2 transmission dynamics in UK

Using a modified version of the susceptible-infectious-recovered (SIR) model to include effects of prevention measures, researchers show patterns in the increase and decrease of coronavirus disease 2019 (COVID-19) cases in the UK.

2 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

E484K mutation is potentially associated with SARS-CoV-2 adaptive fitness

A team of Brazilian scientists has recently conducted genomic and phylogenetic analyses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome to understand the viral evolution process better. Their analyses reveal that the E484K mutated variant of SARS-CoV-2 is present in three different lineages in four Brazilian regions and that the mutation may serve as a common solution for viral evolution.

31 Jan 2021

Genomic News and Research

New platform could help advance genomic medicine research, drug discovery

CRISPR genomic editing to obtain more productive and nutritive plant varieties

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Why the U.S. is underestimating Covid reinfection

COVID-19 pandemic and nanotechnology

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

Study shows how bacteriophage lysis genes could be key to developing new antibiotics

Researchers develop systems to detect an atypical fungus responsible for severe pneumonia

European Union funds new project to improve personalized treatments for ovarian cancer

Researchers to create computational models to improve treatments for ovarian cancer

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Scientists identify genomic signatures of long-term survival in luminal breast cancer patients

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Genomic study suggests SARS-CoV-2 clade 20C was imported into Japan from the US

Researchers develop new modeling to map SARS-CoV-2 transmission dynamics in UK

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

E484K mutation is potentially associated with SARS-CoV-2 adaptive fitness

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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