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Air surveillance of SARS-CoV-2 and other respiratory pathogens

A recent study posted to the medRxiv* preprint server reported severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detection in air samples from real-world congregate settings.

4 Apr 2022

The SAVE initiative to monitor the impact of SARS-CoV-2 variants

The SAVE initiative assesses the impact of SARS-CoV-2 variants on diagnostics, vaccines, and therapies, as well as communicating public health dangers.

4 Apr 2022

BNT162b2 booster vaccine provides equal protection against BA.1 and BA.2

Researchers compare the neutralization of BA.1 and BA.2 strains in immunized people who had received two doses and a booster BNT162b2 mRNA vaccine.

4 Apr 2022

The emergence and limited spread of the Mu SARS-CoV-2 variant

A recent report provides insights into the restricted worldwide spread of the SARS-CoV-2 Mu (B.1.621) variant.

4 Apr 2022

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

Researchers examined whether varied allelic frequencies of the HLA gene in people of different ancestral origins were associated with increased susceptibility to SARS-CoV-2 infection and disease severity.

4 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

Human genome sequenced in its entirety for the first time

An international team of almost one hundred scientists has uncovered the complete, gap-free human genome by deciphering the remaining and hitherto unknown sequences – opening the door for novel approaches to treat various diseases. This seminal, historical study is published in the renowned journal Science.

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

Researchers conduct a massive exome-wide genome study to explore the connections between gene variants/deleterious mutations and COVID-19 outcomes.

3 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

1 Apr 2022

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

In a paper in the journal Nature, Los Alamos National Laboratory scientists Bette Korber, Hyejin Yoon, Will Fischer and James Theiler, among nearly 130 authors from institutions around the world, describe their groundbreaking collaborative work, "Defining the risk of SARS-CoV-2 variants on immune protection."

1 Apr 2022

Research illuminates why immune disorders affect only one of two identical twins

Scientists have long queried the causes of immune disorders in only one of two identical twins with identical genes. New research from the Wellcome Sanger Institute, the Josep Carreras Leukaemia Research Institute in Spain and their collaborators, has found the answer lies in both alterations in immune cell-cell communication and the epigenome, the host of biological processes that regulate how our genes function.

1 Apr 2022

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

In a new study, researchers developed a whole-genome sequencing pipeline based on nanopore technology for the rapid identification of genetic variants.

1 Apr 2022

Therapeutic antibodies against filoviruses including Ebola and Marburg

Researchers discuss the development and structural characterization of therapeutic monoclonal antibodies targeting the surface glycoprotein of filoviruses.

31 Mar 2022

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

UW Medicine genome scientists were among the leading contributors to the publication of the first complete, gapless sequence of a human genome announced this week by the National Human Genome Research Institute.

31 Mar 2022

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

When they're prepared for transport, apples and other fruits are often treated with a fungicide to prevent spoilage and extend shelf life.

31 Mar 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Inconsistency in disease severity across SARS-CoV-2 variants

Researchers determine how the severity of successively dominant SARS-CoV-2 variants has changed since the beginning of the pandemic.

30 Mar 2022

Scientists create a biobank of 87 triple-negative breast cancer organoids

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived from cancer or healthy cells.

30 Mar 2022

Genome News and Research

Air surveillance of SARS-CoV-2 and other respiratory pathogens

The SAVE initiative to monitor the impact of SARS-CoV-2 variants

BNT162b2 booster vaccine provides equal protection against BA.1 and BA.2

The emergence and limited spread of the Mu SARS-CoV-2 variant

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

Human genome sequenced in its entirety for the first time

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

Research illuminates why immune disorders affect only one of two identical twins

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

Therapeutic antibodies against filoviruses including Ebola and Marburg

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Inconsistency in disease severity across SARS-CoV-2 variants

Scientists create a biobank of 87 triple-negative breast cancer organoids

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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