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Diabetes drug blunts exercise-induced health improvements

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

7 Nov 2025

Intensive mind-body retreat rapidly alters brain function and blood biology

Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques, including meditation and healing practices, produced rapid and wide-ranging changes in brain function and blood biology.

6 Nov 2025

Can creatine help with depression? New review says results are inconclusive

Creatine supplementation may modestly reduce depressive symptoms, but the effect is small, uncertain, and likely influenced by study bias. The evidence remains of very low quality, highlighting the need for larger, well-designed clinical trials.

6 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

Long-term study shows peanut patch treatment builds tolerance in toddlers

New research presented at the 2025 Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) offers encouraging news for parents of young children with peanut allergies.

6 Nov 2025

Researchers identify patient response patterns to novel schizophrenia medication

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

6 Nov 2025

Experimental intranasal vaccine triggers broad immune response against multiple strains of H5N1

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) reported encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 "bird flu".

6 Nov 2025

Rituximab shows remarkable success in adults with relapsing nephrotic syndrome

One monoclonal antibody, rituximab, can work wonders for the treatment of children with frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome.

5 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Urolithin A, a natural postbiotic known to trigger mitophagy, rejuvenated key immune cell functions in healthy middle-aged adults after 28 days. The trial showed a shift toward a youthful, energy-efficient CD8⁺ T-cell profile and enhanced bacterial clearance without inflammatory side effects.

3 Nov 2025

Research shows citrus and grape compounds may protect against type 2 diabetes

A six-month clinical trial found that a supplement combining citrus and grape extracts, hesperidin, and chromium significantly reduced fasting blood glucose in prediabetic adults. Participants also saw improved cholesterol and triglyceride levels, returning many to normal metabolic health.

2 Nov 2025

Antibiotic use within 24 hours of birth reduces wound severity in childbirth injuries

Giving antibiotics to women within 24 hours of an obstetric tear during childbirth is associated with a reduced risk of larger/clinically relevant wound complications, find the results of a clinical trial from Denmark published by The BMJ today.

30 Oct 2025

WHO reviews highlight limited long-term data on GLP-1 drug safety

Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform upcoming guidelines on the use of these drugs to treat obesity.

30 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 Oct 2025

Precursor of dopamine increases willingness to wait for larger delayed rewards

A research team from the University of Cologne conducted one of the most comprehensive studies on dopamine and decision-making in humans so far, providing evidence for effects of the former on the latter.

28 Oct 2025

What Britain’s post-war sugar rationing teaches us about long-term heart health

A BMJ study found that individuals exposed to sugar rationing during their first 1,000 days of life had significantly lower risks of heart attack, stroke, and heart failure in adulthood. Early-life sugar restriction was linked to a 2.5-year delay in cardiovascular disease onset, suggesting long-term benefits for heart health.

26 Oct 2025

Semaglutide protects the heart beyond weight loss, SELECT trial shows

Semaglutide lowered the risk of major adverse cardiovascular events across all body weight and waist circumference levels in people with overweight or obesity and cardiovascular disease. Early waist reduction explained only a third of this benefit, showing that semaglutide’s heart protection extends beyond fat loss.

26 Oct 2025

Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

The federal Food and Drug Administration today approved a new menopause drug that reduces hot flashes and night sweats after the drug was successfully tested at UVA Health and other sites in the United States and around the world.

24 Oct 2025

Semaglutide can offer important heart benefits that go beyond weight loss

A new analysis of the SELECT trial – the largest and longest clinical trial to date examining the cardiovascular benefits of semaglutide (a medication used to support weight loss and diabetes management) – confirms it also lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don't have diabetes.

23 Oct 2025

Placebo News and Research

Diabetes drug blunts exercise-induced health improvements

Intensive mind-body retreat rapidly alters brain function and blood biology

Can creatine help with depression? New review says results are inconclusive

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term study shows peanut patch treatment builds tolerance in toddlers

Researchers identify patient response patterns to novel schizophrenia medication

Experimental intranasal vaccine triggers broad immune response against multiple strains of H5N1

Rituximab shows remarkable success in adults with relapsing nephrotic syndrome

New review illuminates the intricate connections between gut microbiota and sleep regulation

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Research shows citrus and grape compounds may protect against type 2 diabetes

Antibiotic use within 24 hours of birth reduces wound severity in childbirth injuries

WHO reviews highlight limited long-term data on GLP-1 drug safety

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

Precursor of dopamine increases willingness to wait for larger delayed rewards

What Britain’s post-war sugar rationing teaches us about long-term heart health

Semaglutide protects the heart beyond weight loss, SELECT trial shows

Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

Semaglutide can offer important heart benefits that go beyond weight loss

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