Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Research asserts ability of DRS technique to characterize healthy and non-healthy tissue

In an article published in the peer-reviewed SPIE publication Journal of Biomedical Optics (JBO), "Influence of neoadjuvant chemotherapy on diffuse reflectance spectra of tissue in breast surgery specimens," research observed across 92 ex vivo breast specimens suggests that there is little to no impact on the optical signatures of breast tissue after neoadjuvant chemotherapy.

27 Nov 2019

Study shows potential of hydromethylthionine treatment for Alzheimer's disease

In a paper published in today's online issue of the Journal of Alzheimer's Disease (DOI 10.3233/JAD-190772), TauRx has reported unexpected results of a pharmacokinetic analysis of the relationship between treatment dose, blood levels and pharmacological activity of the drug hydromethylthionine on the brain in over 1,000 patients with mild-to-moderate Alzheimer's disease.

27 Nov 2019

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Cleveland-based startup will use federal grant to develop AI tools for TB detection

Cleveland--Diascopic LLC, a Cleveland-based medical research company that develops diagnostic technology, will use a highly competitive federal grant to develop and apply new artificial intelligence and digital pathology tools for detecting tuberculosis.

26 Nov 2019

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

Extra virgin olive oil boosts brain power

Researchers from the Lewis Katz School of Medicine at Temple University have found that extra virgin olive oil (EVOO) could help boost brain power and help halt the progression of the effects of aging on the brain. The study was published in the latest issue of the journal Aging Cell, and it was titled, “Extra virgin olive oil improves synaptic activity, short‐term plasticity, memory, and neuropathology in a tauopathy model.”

26 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

25 Nov 2019

Novel solution could produce accurate, automated placental diagnostic reports

Placentas can provide critical information about the health of the mother and baby, but only 20 percent of placentas are assessed by pathology exams after delivery in the U.S. The cost, time and expertise required to analyze them are prohibitive.

25 Nov 2019

Study shows how drinking patterns reprogram circadian metabolism in the liver

Drinking alcohol is a widespread habit in modern society and can have serious metabolic consequences. Recent studies have uncovered the interplay between nutrition, metabolism and circadian rhythms. But, until now, little has been done to understand the effects of alcohol consumption on circadian metabolism.

22 Nov 2019

Higher antibiotic exposure linked to increased risk of Parkinson's disease

Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson's disease according to a recently published study by researchers form the Helsinki University Hospital, Finland.

22 Nov 2019

Kessler Foundation to study use of minimally invasive treatment for meniscal tears

Kessler Foundation received a $590,000 award from The Geneva Foundation for a three-year study of the use of a an experimental minimally invasive treatment for meniscal tears--the injection of autologous micro-fragmented adipose tissue into the knee joint.

21 Nov 2019