Cholesterol News and Research

RSS

Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

In the United States, one in every 250 people has inherited a genetic variant that leads to dangerously high cholesterol levels from birth.

10 Nov 2025

Coronary artery calcium score could help predict overall health and all-cause mortality

In a new study of more than 40,000 patients, researchers at Intermountain Health in Salt Lake City have found that patients who have no evidence of calcium in their coronary arteries are not only significantly less likely to die from heart conditions – including heart attacks and heart failure– but also are at reduced risk of death from non-cardiac medical conditions.

10 Nov 2025

New delivery particle could make mRNA vaccines cheaper and more effective

A new delivery particle developed at MIT could make mRNA vaccines more effective and potentially lower the cost per vaccine dose.

7 Nov 2025

Major gaps found in cholesterol management for young adults

Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or "bad" cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's 2025 Scientific Sessions.

6 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

Heart damage during middle age linked to greater dementia risk in later life

People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by UCL (University College London) researchers.

5 Nov 2025

What’s driving England’s rise in chronic illness? Ageing, not lifestyle, researchers find

A new Nature Communications study using the IMPACTNCD microsimulation model projects that England’s major illness burden will rise sharply by 2043, even with substantial lifestyle improvements. Population ageing, not modifiable risk factors, remains the dominant driver of future multimorbidity.

5 Nov 2025

How gut microbes shape sleep: New review reveals microbiome clues to insomnia and apnea

A new Brain Medicine review maps how gut microbes influence sleep disorders, from insomnia and sleep apnea to circadian disruption, via bile acids, neurotransmitters, and immune pathways. The findings highlight gut-driven targets for improving sleep quality through diet, probiotics, and microbiome modulation.

5 Nov 2025

Action needed to fix gender gap in cardiac rehab

Addressing barriers to cardiac rehab for women is essential. The AHA's guidelines focus on enhancing access and promoting effective heart health strategies.

5 Nov 2025

Common cholesterol drugs found to speed up PFAS removal from the body

Certain medicines can cause the environmental toxin PFAS to be eliminated from the body faster, according to a study at the University of Gothenburg.

4 Nov 2025

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

A new study by investigators from Mass General Brigham shows that patients with traumatic spinal cord injuries (TSCI) are at a higher risk of developing a myriad of chronic health problems, regardless of age, location of the injury and prior health status.

4 Nov 2025

UCLA experts call for individualized heart monitoring in breast cancer survivors

As breast cancer survival rates continue to climb - 4.3 million women in the U.S. are currently living with a history of the disease and in the next 10 years that number is expected to rise by another million - heart health has become an increasingly important part of survivorship care.

4 Nov 2025

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Women who consumed more ultra-processed foods (UPFs) showed distinct DNA methylation patterns, mostly reduced across key gene regions. These exploratory findings suggest that high UPF intake may influence gene regulation through epigenetic mechanisms.

4 Nov 2025

Swapping meat for plant-based options cuts fat but lowers protein, study finds

Replacing meat with plant-based or mycoprotein alternatives in UK diets lowers saturated fat and boosts fiber but reduces protein intake, especially for teens and older adults. The overall saturated fat reduction is too small to meaningfully affect cholesterol levels, researchers report in npj Science of Food.

4 Nov 2025

New study finds no increased risk of heart and brain infarctions for transgender women

Contrary to previous research, transgender women who use the hormone oestradiol for their transition do not have an increased risk of heart attack and stroke compared to men in the general Dutch population.

4 Nov 2025

How walnuts combat inflammation and oxidative stress in the body

This review in Food Science & Nutrition synthesizes evidence showing that walnuts (Juglans regia L.) exert potent antioxidant, anti-inflammatory, apoptosis-regulatory, and immunomodulatory effects through bioactive compounds influencing mitochondrial, cytokine, and redox pathways.

3 Nov 2025

Fewer women participate in cardiac rehabilitation, despite a slew of benefits

For someone who has heart surgery or experiences a major cardiovascular event, cardiac rehabilitation can significantly improve their short and long term recovery.

3 Nov 2025

Combined analysis of three blood tests enhances heart attack risk prediction

A combined analysis of blood tests to measure three biomarkers linked to higher risk of cardiovascular disease-lipoprotein a (Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)-may help identify high-risk individuals earlier and guide more personalized prevention strategies, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Low-dose aspirin helps reduce the incidence of major cardiovascular event among diabetic individuals

People with Type 2 diabetes (T2D) and an elevated risk for cardiovascular disease (CVD) who took low-dose aspirin were less likely to experience a major cardiovascular event, including heart attack, stroke or death, than people with T2D at similar CVD risk who did not take low-dose aspirin, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Cholesterol News and Research

Further Reading

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

Coronary artery calcium score could help predict overall health and all-cause mortality

New delivery particle could make mRNA vaccines cheaper and more effective

Major gaps found in cholesterol management for young adults

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Heart damage during middle age linked to greater dementia risk in later life

What’s driving England’s rise in chronic illness? Ageing, not lifestyle, researchers find

How gut microbes shape sleep: New review reveals microbiome clues to insomnia and apnea

Action needed to fix gender gap in cardiac rehab

Common cholesterol drugs found to speed up PFAS removal from the body

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

UCLA experts call for individualized heart monitoring in breast cancer survivors

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Swapping meat for plant-based options cuts fat but lowers protein, study finds

New study finds no increased risk of heart and brain infarctions for transgender women

How walnuts combat inflammation and oxidative stress in the body

Fewer women participate in cardiac rehabilitation, despite a slew of benefits

Combined analysis of three blood tests enhances heart attack risk prediction

Low-dose aspirin helps reduce the incidence of major cardiovascular event among diabetic individuals

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News