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Healthy gut microbiota contributes to normal brain function, study shows

Depression is a mental disorder that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is vital for the development of effective therapeutic strategies.

11 Dec 2020

New AI tool could make breast cancer treatment less expensive and more readily available

Imagine being a doctor and having a precocious resident permanently by your side, giving you brilliant insight into disease and helping you to identify the best treatment path for your patients.

11 Dec 2020

Researchers analyze prevalence of COVID-19 in human post-mortem ocular tissues

COVID-19 has been found in conjunctival swabs and tears of infected patients, according to a new study published in The Ocular Surface.

11 Dec 2020

MEDS433 hinders SARS-CoV-2 replication

A paper that recently appeared in the preprint server bioRxiv* reports the powerful activity of a compound named MEDS433 against this virus.

10 Dec 2020

Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies.

10 Dec 2020

Organic hydrogels can be a promising candidate for building long-term functioning glucose biosensors

In a new study, published online in the journal American Chemical Society (ACS) Applied Polymer Materials, scientists at Texas A&M University reported they have designed a hydrogel membrane that may be used to house optical glucose sensing materials, toward building a biosensor for monitoring sugar levels in diabetics.

10 Dec 2020

Modulation of oral microbiota impacts the cardiovascular benefits of sport

Exercise plays a key role in maintaining good physical and mental health throughout life. There is an increasing amount of scientific evidence that some of the immune system and metabolism benefits provided by sport are related to the thousands of millions of bacteria that colonize the digestive tract, from the mouth to the intestines, known as microbiota.

9 Dec 2020

New consortium aims to understand principles underlying the formation of coronaviruses

The University of California, Riverside, is the recipient of a 2021 UC Multicampus Research Programs and Initiatives, or MRPI, award allowing the campus to put together a UC Coronavirus Assembly Research Consortium.

9 Dec 2020

Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Researchers say they've identified a way to disrupt a process that promotes the growth of pancreatic cancers -- one of the most difficult and deadly cancers to treat.

9 Dec 2020

Chemists identify a new method to make valuable hydrocarbons

Inspired by light-sensing bacteria that thrive near hot oceanic vents, synthetic chemists at Rice University have found a mild method to make valuable hydrocarbons known as olefins, or alkenes.

8 Dec 2020

Reductive stress promotes protein aggregation in neuroblastoma cells, impairs neurogenesis

Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at the other end of the spectrum -- reductive stress, or RS -- may affect neurons.

8 Dec 2020

Amilorides reduce SARS-CoV-2 viral replication in vitro

A new U.S. study published on the bioRxiv preprint server reports the use of an amiloride-based scaffold that targets a viral RNA structure known to be essential in viral replication in the 5’-untranslated region (UTR) of the virus. The researchers say this heralds the application of these molecules as chemical probes to explore viral biology and produce specific antivirals targeting RNA regions of the coronavirus genome.

8 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Research illuminates regulatory mechanism of ubiquitin-proteasome system in DNA damage repair

An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light.

8 Dec 2020

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles.

8 Dec 2020

Dihydrogen phosphate anions bind together even in dilute solutions, study shows

Scientists at UNSW Sydney, together with collaborators from Western Sydney University and The Netherlands, were surprised to find that dihydrogen phosphate anions - vital inorganic ions for cellular activity - bind with other dihydrogen phosphate anions despite being negatively charged.

8 Dec 2020

Molecule News and Research

Healthy gut microbiota contributes to normal brain function, study shows

New AI tool could make breast cancer treatment less expensive and more readily available

Researchers analyze prevalence of COVID-19 in human post-mortem ocular tissues

MEDS433 hinders SARS-CoV-2 replication

Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

Organic hydrogels can be a promising candidate for building long-term functioning glucose biosensors

Modulation of oral microbiota impacts the cardiovascular benefits of sport

New consortium aims to understand principles underlying the formation of coronaviruses

Tomatoes could become a new, natural source of Parkinson's disease drug

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Chemists identify a new method to make valuable hydrocarbons

Reductive stress promotes protein aggregation in neuroblastoma cells, impairs neurogenesis

Amilorides reduce SARS-CoV-2 viral replication in vitro

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Study findings can guide personalized breast cancer therapies based on melatonin

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Research illuminates regulatory mechanism of ubiquitin-proteasome system in DNA damage repair

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Dihydrogen phosphate anions bind together even in dilute solutions, study shows

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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