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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Iowa researcher uses new technique to verify brain's master switch

The protein that has long been suspected by scientists of being the master switch allowing brains to function has now been verified by an Iowa State University researcher.

10 May 2010

Study: PDE5 inhibitors may increase permeability of blood brain barrier to Herceptin

New research by scientists at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute suggests that a drug currently approved to treat erectile dysfunction may significantly enhance the delivery of the anti-cancer drug Herceptin to certain hard-to-treat brain tumors.

10 May 2010

Majority of Iraq and Afghanistan veterans experience multi-symptom pain disorders

Dr. Gallagher further noted the VA's pain care challenge is magnified by a 90 percent injury survivor rate from these conflicts compared with only 40 percent in the Vietnam War. VA clinicians are now challenged to manage pain in blast survivors with one or several other consequences of blast, such as head injuries causing mild to severe TBI, physical disfigurement and social stigma, emotional trauma, and often post traumatic stress disorder (PTSD).

10 May 2010

A cutting-edge symposium sheds light on the possibilities of molecular neuroimaging

SNM's Molecular Imaging Center of Excellence wrapped up its Molecular Neuroimaging Symposium today in Bethesda, Md., at the Natcher Auditorium of the National Institutes of Health (NIH).

10 May 2010

First 3-year results of world's largest temporomandibular joint disorder study reported at APS meeting

Scientists with the University of Maryland Dental School and collaborators at three other major universities will report results from the first three years of the world's largest study yet of a mysterious yet common pain syndrome involving the jaw at 8:30 a.m.on May 7 at the annual scientific meeting of the American Pain Society (APS). This year it is being held at the Baltimore Convention Center.

7 May 2010

Closer to understanding age-related memory loss and drug to boost memory

The world's scientific community may be one step closer to understanding age-related memory loss, and to developing a drug that might help boost memory. In an editorial published May 7 in Science, J. David Sweatt, Ph.D., chair of the University of Alabama at Birmingham (UAB) Department of Neurobiology, says that drugs known as histone deacetylase inhibitors are showing great promise in stopping memory loss - and even in boosting the formation of memory in animal models.

7 May 2010

Researchers investigate effects of fatigue on neurosurgery resident performance

There are more than 6,000 U.S. hospitals, with approximately 3,500 actively practicing board-certified neurosurgeons serving a population of over 303 million people. About 150 neurosurgery residents graduate every year from the 99 accredited U.S. neurosurgery training programs.

7 May 2010

Researchers analyze relationship between extent of resection and outcome in patients with glioblastoma

Gliomas arise from the supporting cells of the brain, called the glia. These cells are subdivided into astrocytes, ependymal cells and oligodendroglial cells (or oligos). These tumors are graded from the lowest grade 1 to highest grade 4, with glioblastoma multiforme being the highest grade and deadliest type of glioma.

7 May 2010

Two-day symposium on molecular neuroimaging

Today, SNM's Molecular Imaging Center of Excellence kicked off a two-day symposium bringing together individuals from multiple scientific disciplines-including chemistry, engineering, physics, molecular biology, neurosciences and imaging sciences-to promote the emerging field of molecular neuroimaging.

7 May 2010

ADDF awards $210,300 to Amicus Therapeutics to evaluate PCs for treating Alzheimer's disease

The Alzheimer's Drug Discovery Foundation announced today that it has awarded a grant of $210,300 to Amicus Therapeutics (Cranbury, NJ) to evaluate small-molecule, orally delivered pharmacological chaperone compounds as a novel approach for treating Alzheimer's disease.

7 May 2010

Study highlights benefits of using endometrial stem cells to restore functioning of brain cells

Stem cells derived from the endometrium (uterine lining) and transplanted into the brains of laboratory mice with Parkinson's disease appear to restore functioning of brain cells damaged by the disease, according to a new study by Yale School of Medicine researchers.

7 May 2010

DNA sequence of amphibian genome sheds light on the study of embryonic development

A pair of University of Houston researchers contributed to the assembly of the first comprehensive DNA sequence of an amphibian genome, which will shed light on the study of embryonic development, with implications for preventing birth defects and more effectively treating many human diseases.

7 May 2010

Neuroscientists show how individual neurons carry significant aspects of sensory processing

Pioneering a novel microscopy method, neuroscientist Arthur Konnerth and colleagues from the Technische Universitaet Muenchen (TUM) have shown that individual neurons carry out significant aspects of sensory processing: specifically, in this case, determining which direction an object in the field of view is moving.

7 May 2010

Medtronic initiates U.S. clinical trial of RestoreSensor neurostimulator in chronic pain patients

Medtronic, Inc. today announced the initiation of a prospective, multi-center, randomized U.S. clinical trial for the RestoreSensorTM neurostimulator that adapts therapy to the changing needs of chronic pain patients by responding automatically to changes in body position and activity in an upright position.

7 May 2010

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Quark Pharmaceuticals, Inc., the world leader in clinical development of RNAi-based therapeutics, announced today that researchers from Pfizer, Inc. presented data on in vivo activity of PF-04523655 at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, being held May 2-6, 2010 in Fort Lauderdale.

7 May 2010

Mouse study may lead to new therapies for Parkinson's disease

Endometrial stem cells injected into the brains of mice with a laboratory-induced form of Parkinson's disease appeared to take over the functioning of brain cells eradicated by the disease.

7 May 2010

Tel Aviv researchers develop microscope-based cell scanner to speed research into fat-busting drugs

Anglers rely on fish finders to help them locate the big catch. Now Tel Aviv University researchers in tissue engineering have developed a "fat finder" that can help scientists accelerate their research into new fat-melting drugs.

7 May 2010

FDA assigns BYDUREON new PDUFA action date of October 22, 2010

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has classified the BYDUREON™ (exenatide for extended-release injectable suspension) complete response as a Class 2 resubmission and assigned a new Prescription Drug User Fee Act (PDUFA) action date of October 22, 2010.

6 May 2010

Intellect Neurosciences signs debt settlement agreement with CARBOGEN AMCIS AG

Intellect Neurosciences, Inc., a biopharmaceutical company focused on development of disease-modifying therapeutic agents for Alzheimer's disease, announced today that it has reached a debt settlement agreement with CARBOGEN AMCIS AG, one of Intellect's largest trade creditors, in connection with prior services rendered.

6 May 2010

Biovail reports 27% increase in first-quarter 2010 total revenues

Biovail Corporation today announced its financial results for the three-month period ended March 31, 2010.

6 May 2010

Brain News and Research

Further Reading

Iowa researcher uses new technique to verify brain's master switch

Study: PDE5 inhibitors may increase permeability of blood brain barrier to Herceptin

Majority of Iraq and Afghanistan veterans experience multi-symptom pain disorders

A cutting-edge symposium sheds light on the possibilities of molecular neuroimaging

First 3-year results of world's largest temporomandibular joint disorder study reported at APS meeting

Closer to understanding age-related memory loss and drug to boost memory

Researchers investigate effects of fatigue on neurosurgery resident performance

Researchers analyze relationship between extent of resection and outcome in patients with glioblastoma

Two-day symposium on molecular neuroimaging

ADDF awards $210,300 to Amicus Therapeutics to evaluate PCs for treating Alzheimer's disease

Study highlights benefits of using endometrial stem cells to restore functioning of brain cells

DNA sequence of amphibian genome sheds light on the study of embryonic development

Neuroscientists show how individual neurons carry significant aspects of sensory processing

Medtronic initiates U.S. clinical trial of RestoreSensor neurostimulator in chronic pain patients

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Mouse study may lead to new therapies for Parkinson's disease

Tel Aviv researchers develop microscope-based cell scanner to speed research into fat-busting drugs

FDA assigns BYDUREON new PDUFA action date of October 22, 2010

Intellect Neurosciences signs debt settlement agreement with CARBOGEN AMCIS AG

Biovail reports 27% increase in first-quarter 2010 total revenues

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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