immunity News and Research

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Aptar Pharma’s intranasal solutions power CastleVax Phase II clinical trials for next-gen COVID-19 vaccine

In a significant step forward for mucosal immunity, Aptar Pharma has announced that its innovative nasal delivery systems are being utilized in CastleVax’s Phase II clinical trial for CVAX-01, an intranasal COVID-19 vaccine candidate.

From Hanson Wade Group - 4th Nasal Formulation & Delivery Summit 16 Feb 2026

Innate immune priming may evolve into a broadly applicable infection-prevention strategy

Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine.

16 Feb 2026

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

15 Feb 2026

Universal famine thresholds may mask unfolding starvation

Recent global crises have exposed the limits of a universal mortality threshold for declaring famine-an approach that can obscure how famine actually unfolds across different populations.

13 Feb 2026

Antibody feedback reshapes B cell selection during immune response

A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes how immune cells are selected during an immune response.

13 Feb 2026

SLAMF6 discovery offers hope for non-responding cancer patients

Cancer researchers working on immunotherapies have made a big discovery: SLAMF6, a molecule on the surface of immune cells that prevents T cells from effectively attacking tumors – and, in mice, they've found a way to neutralize it.

12 Feb 2026

Study uncovers immune trigger behind vaccine-induced immune thrombocytopenia and thrombosis

A global research collaboration of scientists from McMaster University (Canada), Flinders University (Australia) and Universitätsmedizin Greifswald (Germany) uncovered why a small number of people developed dangerous blood clots after either receiving certain COVID‑19 vaccines or experiencing a natural adenovirus infection, and the answer lies in an unexpected case of misdirected targeting by the immune system.

11 Feb 2026

New strategy harnesses pre-existing antiviral immunity to boost anti-tumor responses

Because many different types of cancer cells overexpress programmed death-ligand 1 (PD-L1), this cell surface protein is a major target of cancer immunotherapy.

11 Feb 2026

Safety perceptions of major vaccines show significant drop over the past three years

In a winter marked by flu outbreaks, the persistence of Covid-19, and surges of measles cases across the United States, an Annenberg survey finds that a sizable majority of Americans think the three vaccines that combat these potentially deadly illnesses are safe to take, although perceptions of the safety of all three vaccines showed a statistically significant drop over the past three years.

10 Feb 2026

Stress hormones rewire immune system during periods of food scarcity

When food is scarce, stress hormones direct the immune system to operate in "low power" mode to preserve immune function while conserving energy, according to researchers at Weill Cornell Medicine.

10 Feb 2026

Engineered wax moths offer ethical alternative to rodents used in research

A scientific breakthrough not only promises faster testing for antimicrobial resistance, but also an ethical solution to the controversial issue of using rodents in research.

10 Feb 2026

Preexisting flu immunity may offer baseline protection against avian influenza

Are seasonal flu antibodies also effective against avian flu? A team from the University of Geneva (UNIGE) has shown that a specific type of antibody associated with the former virus—already present throughout the population—may offer baseline protection against the latter.

10 Feb 2026

AI model accelerates antibody production and clone selection

As instigators of immunity, monoclonal antibodies are marvels of modern medicine, lab-made proteins that can treat cancers, autoimmune diseases, and many other conditions.

9 Feb 2026

Influenza viruses can directly impair heart function

Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk of a heart attack or other major cardiovascular event.

9 Feb 2026

Binghamton University receives $2.5 million to develop a next-generation avian flu vaccine

Outbreaks of avian flu at U.S. poultry farms led to more than $1.5 billion in losses over the last two years and drove egg prices to all-time highs in 2025.

6 Feb 2026

European collaboration transforms immune cell data into cancer biomarkers

World Cancer Day, marked on 4 February, is an international day dedicated to raising awareness of cancer, and to encouraging its prevention, detection and treatment.

6 Feb 2026

Griffith researchers on the cusp of new vaccine to prevent chikungunya

Griffith University researchers are on the cusp of a new vaccine to prevent chikungunya, a global health threat which attacks human joint tissue.

6 Feb 2026

11th Innate Killer Summit returns to San Diego, showcasing clinical data that signals renewed momentum in NK cell therapy

The 11th Innate Killer Summit returns, bringing together global leaders advancing natural killer (NK) cell–based immunotherapies.

From Hanson Wade Group - 11th Innate Killer Summit 6 Feb 2026

Computational method clarifies microbial signals in tumor sequencing

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

5 Feb 2026

Study reveals evidence of silent mpox exposure in healthy Nigerians

New evidence suggests that mpox may be circulating quietly among healthy Nigerians, with some infections occurring without the symptoms that typically trigger detection by health authorities.

5 Feb 2026

immunity News and Research

Aptar Pharma’s intranasal solutions power CastleVax Phase II clinical trials for next-gen COVID-19 vaccine

Innate immune priming may evolve into a broadly applicable infection-prevention strategy

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Universal famine thresholds may mask unfolding starvation

Antibody feedback reshapes B cell selection during immune response

SLAMF6 discovery offers hope for non-responding cancer patients

Study uncovers immune trigger behind vaccine-induced immune thrombocytopenia and thrombosis

New strategy harnesses pre-existing antiviral immunity to boost anti-tumor responses

Safety perceptions of major vaccines show significant drop over the past three years

Stress hormones rewire immune system during periods of food scarcity

Engineered wax moths offer ethical alternative to rodents used in research

Preexisting flu immunity may offer baseline protection against avian influenza

AI model accelerates antibody production and clone selection

Influenza viruses can directly impair heart function

Binghamton University receives $2.5 million to develop a next-generation avian flu vaccine

European collaboration transforms immune cell data into cancer biomarkers

Griffith researchers on the cusp of new vaccine to prevent chikungunya

11th Innate Killer Summit returns to San Diego, showcasing clinical data that signals renewed momentum in NK cell therapy

Computational method clarifies microbial signals in tumor sequencing

Study reveals evidence of silent mpox exposure in healthy Nigerians

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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