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Living digital camera: scientists capture light patterns in DNA for image storage

Researchers described a technique of capturing two-dimensional (2D) light patterns into DNA.

6 Jul 2023

Bionano announces the Stratys™ system for OGM and VIA™ software for hematologic malignancies

Bionano Genomics, Inc. today announced the Stratys™ system for high throughput optical genome mapping (OGM) and VIA™ software for visualization, interpretation and reporting of genome analysis for OGM, microarrays and next-generation sequencing (NGS) data in one integrated software platform.

From Bionano Genomics, Inc. 5 Jul 2023

Mount Sinai launches first-of-its-kind center for ophthalmic AI

The Icahn School of Medicine at Mount Sinai has launched the Center for Ophthalmic Artificial Intelligence and Human Health, the first of its kind in New York and one of the first in the United States.

5 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Towards Zika preparedness: immunogenicity insights from vaccine research

Study assesses the safety and immunogenicity of an inactivated Zika virus vaccine candidate.

30 Jun 2023

Advances in influenza research

This interview with Dr. Mohammad S Safiarian, Associate Product Manager at Sino Biological, discusses the advances in influenza research and how effective vaccines are developed.

From Sino Biological Inc. 30 Jun 2023

Cyanotriazole compounds can selectively and rapidly kill trypanosome parasites, study shows

Cyanotriazole compounds are fast-acting topoisomerase II poisons that can selectively and rapidly kill trypanosome parasites that cause Chagas disease and African sleeping sickness, according to a new study.

29 Jun 2023

Study shows promising prospects for automating 3D-DSRT in drug testing

The June 2023 issue of SLAS Discovery contains one review article, five full-length articles and two technical briefs covering spheroid models, 3D cell high-throughput screening (HTS) applications for treating Alzheimer's and other drug discovery research.

29 Jun 2023

SickKids researchers discover new way to attack treatment-resistant TB infections

In the face of growing antibiotic resistance among bacterial infections, scientists at The Hospital for Sick Children (SickKids) have delved into the molecular science behind treatment-resistant tuberculosis.

28 Jun 2023

New rapid automated viral plaque detection system enabled by holography and deep learning

In a new paper published in Nature Biomedical Engineering, a team of scientists led by Professor Aydogan Ozcan from the Electrical and Computer Engineering Department at UCLA and an associate director of the California NanoSystems Institute, developed a rapid, stain-free, and automated viral plaque detection system enabled by holography and deep learning.

23 Jun 2023

Key viral protein produced by influenza A can shred a host cell's genetic materials, finds study

Influenza A is one of two influenza viruses that fuel costly annual flu seasons and is a near constant threat to humans and many other animals. It's also responsible for occasional pandemics that, like the one in 1918, leave millions dead and wreak havoc on health systems and wider society.

23 Jun 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

A single mutation stands in the way of a drug's effectiveness. Understanding it helps find new therapeutic approaches.

21 Jun 2023

INTEGRA Biosciences’ pipettes help to advance cancer drug discovery

The Institute for Cancer Research (ICR), part of the University of London, is using VIAFLO electronic pipettes from INTEGRA Biosciences to streamline its preclinical drug screening and translational medicine workflows.

From INTEGRA Biosciences 20 Jun 2023

Sphere Fluidics’ Pico-Mine platform chosen by Biosyntia to accelerate synthetic biology and metabolic workflows

Platform selected to accelerate precision fermentation workflows, to support more sustainable and cost-effective manufacturing for active ingredients in vitamins and bioactive.

From Fluidic Sciences and Sphere Bio 20 Jun 2023

Complete genomics announces updated mission and new partnerships on 18th anniversary

Complete Genomics, Inc., a pioneering genomics company, today unveiled updated mission/vision statement to reflect renewed ambitions in taking on more for a better world, in celebration of its 18th anniversary.

From MGI 15 Jun 2023

Cerillo showcases wireless, scalable, off-the-shelf co-culture solution

Cerillo, a biotechnology company at the forefront of developing advanced research platforms for the study of the microbiome, will host demonstrations of the company’s new co-culture duet system at ASM Microbe 2023 from June 16-18th in Houston, Texas at booth #704.

From Cerillo 15 Jun 2023

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.