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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

This 3D modeling reveals how SARS-CoV-2 attacks

Now, researchers at the Garvan Institute of Medical Research, Darlinghurst in Australia, CSIRO Data61, and the School of Biotechnology and Biomolecular Sciences (UNSW) demonstrated the most comprehensive analysis of the three-dimensional structure of SARS-CoV-2, providing a new insight into how the virus infects cells and replicates.

16 Sep 2021

New study reveals chemical steps in an important cellular modification process

The chemical steps in an important cellular modification process that adds a chemical tag to some RNAs have been revealed in a new study. Interfering with this process in humans can lead to neuronal diseases, diabetes, and cancers.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

Heart inflammation more common among men following mRNA-based COVID-19 vaccination

Researchers in the UK have assessed data from around the world to better understand the frequency and risk factors for myocarditis and pericarditis following immunization with messenger RNA (mRNA)-based vaccines designed to protect against coronavirus disease 2019 (COVID-19).

16 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

A new study focused on in vitro antiviral activity in various cell models and in vivo therapeutic efficacy of oral GS-621763 in a mouse model of SARS-CoV-2 pathogenesis.

15 Sep 2021

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Researchers in the United States have developed a new automated approach to detecting variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that have increased growth rates over other lineages.

15 Sep 2021

Effectiveness of mRNA-1273 against asymptomatic infection, COVID-19 diagnosis, and severe outcomes

A Moderna phase 3 trial provides evidence that the RNA-1273 vaccine is highly effective in preventing disease following infection SARS-CoV-2.

14 Sep 2021

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Now, a new study posted to the bioRxiv* server by scientists from the University of Washington explores the use of NanoString’s GeoMx digital spatial profiling (DSP) to investigate CG caused by HIV and SARS-Cov-2 infections.

14 Sep 2021

Study compares DNA extraction and amplification methods used for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

14 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Study suggests SARS-CoV-2 circulation in schools is limited

A new study discusses existing evidence of SARS-CoV-2 transmission in an educational setting.

13 Sep 2021

Rutgers study examines link between COVID-19 and memory loss, dementia

A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, "brain fog," and dementia.

13 Sep 2021

Does SARS-CoV-2 contamination in operating and birthing room settings pose risks for health care workers?

A new study assesses the risk of contamination in the operating room and birthing suite environment.

13 Sep 2021

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

A recent study examined the ability of SARS-CoV-2 to impact DNA damage response and telomere stability in Vero E6 cells.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

An investigation of SARS-CoV-2 infections among Australian passengers on the Diamond Princess cruise ship

The Diamond Princess Cruise ship left Yokohama (Japan) on 20 January 2020, for a fourteen-day tour with shore excursions in Japan, Hong Kong, Vietnam, and Taiwan. Unfortunately, one of the passengers who complained of mild dry cough was later confirmed to be SARS-CoV-2 positive. In due course, 19% of the passengers were infected with the virus, and thirteen people died.

13 Sep 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

RNA News and Research

Further Reading

This 3D modeling reveals how SARS-CoV-2 attacks

New study reveals chemical steps in an important cellular modification process

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Heart inflammation more common among men following mRNA-based COVID-19 vaccination

Aptamers for Targeting SARS-CoV-2 Proteins

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Effectiveness of mRNA-1273 against asymptomatic infection, COVID-19 diagnosis, and severe outcomes

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Study compares DNA extraction and amplification methods used for microbiome research

New SARS-CoV-2 mechanism of host gene suppression

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Study suggests SARS-CoV-2 circulation in schools is limited

Rutgers study examines link between COVID-19 and memory loss, dementia

Does SARS-CoV-2 contamination in operating and birthing room settings pose risks for health care workers?

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

An investigation of SARS-CoV-2 infections among Australian passengers on the Diamond Princess cruise ship

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

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