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Comprehensive peri-operative care guidelines address needs of transgender and gender-diverse patients

New guidance on peri-operative care of transgender and gender-diverse individuals is today published in Anaesthesia (the journal of the Association of Anaesthetists) to guide best practice to ensure the safety and dignity of transgender and gender-diverse people in the peri-operative period.

23 Jul 2024

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors.

23 Jul 2024

Financial incentives boost meal replacement therapy success in severely obese adolescents

Adolescents with severe obesity who received meal-replacement therapy plus financial incentives experienced a greater reduction in body mass index compared to those who received meal replacement therapy alone, according to recent findings published in JAMA Pediatrics.

23 Jul 2024

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis.

23 Jul 2024

Lario Therapeutics awarded $6M Grant from The Michael J. Fox Foundation for Parkinson’s Research

Award supports preclinical research of Lario’s CaV2.3 calcium channel inhibitors as a novel disease-modifying approach for treatment of Parkinson's disease.

23 Jul 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

New study sheds light on irregular heartbeat risk

Two new, basic animal research studies shed light on alcohol consumption and the heart. The first study may help explain why binge drinking sometimes causes an irregular heartbeat and a possible way to prevent it. The second study investigated why alcohol may have a negative impact on heart function in women taking estrogen replacement therapy.

23 Jul 2024

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

A new research paper was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma."

22 Jul 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Study finds limited evidence for massage therapy's effectiveness in pain relief

A study in JAMA Network Open reviews evidence on massage therapy's effectiveness in relieving pain, finding moderate certainty for some conditions but overall low certainty for most.

21 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Published in Clinical Cancer Research, results of a preclinical study led by investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Stem Cells and Cancer Group, headed by Héctor G. Palmer, pave the way for systemic targeted therapy in patients with pseudomyxoma peritonei, a rare form of cancer with very few therapeutic options available.

19 Jul 2024

Collaborative grant program boosts health research across Tennessee

Researchers from the University of Tennessee Health Science Center College of Medicine-Knoxville; the University of Tennessee, Knoxville; and the University of Tennessee Health Science Center Office of Research understand the challenges affecting the health and wellness of Tennesseans.

19 Jul 2024

Physical modulation of the tumor microenvironment to enhance cancer therapy

Announcing a new article publication for BIO Integration journal. The tumor microenvironment (TME) has a crucial role in tumor development, metastasis, and recurrence.

19 Jul 2024

Does hormone-modulating therapy for breast cancer treatment affect risk for Alzheimer disease and related dementias?

The association between hormone-modulating therapy (HMT) for breast cancer treatment and the risk of developing Alzheimer's disease and related dementias.

19 Jul 2024

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product.

19 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Medical debt doubles risk of skipping mental health care for depression and anxiety

Medical debt is significantly more prevalent among adults with depression or anxiety compared to adults without these mental disorders, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Among adults with depression or anxiety, those with medical debt were twice as likely to report having delayed or forgone mental health care in the previous 12 months compared to those without medical debt.

19 Jul 2024

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Researchers found that high-dose psilocybin significantly disrupts brain functional connectivity, particularly in the default mode network, with lasting effects linked to therapeutic benefits.

18 Jul 2024

Therapy News and Research

Comprehensive peri-operative care guidelines address needs of transgender and gender-diverse patients

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Financial incentives boost meal replacement therapy success in severely obese adolescents

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Lario Therapeutics awarded $6M Grant from The Michael J. Fox Foundation for Parkinson’s Research

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

New study sheds light on irregular heartbeat risk

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Study finds limited evidence for massage therapy's effectiveness in pain relief

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Collaborative grant program boosts health research across Tennessee

Physical modulation of the tumor microenvironment to enhance cancer therapy

Does hormone-modulating therapy for breast cancer treatment affect risk for Alzheimer disease and related dementias?

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Medical debt doubles risk of skipping mental health care for depression and anxiety

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

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