Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Cold Spring Harbor Protocols features organ and cell culture methods

Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory.

4 Nov 2008

YM Biosciences reports on early trials of nimotuzumab in brain metastases and high-grade glioma

YM BioSciences Inc. has announced data from two clinical trials of nimotuzumab, its humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR). Preliminary results from the two trials which are evaluating nimotuzumab in combination with radiation therapy for the treatment of brain metastases and high-grade gliomas, conducted by YM's licensor, were presented at the 2008 EORTC-NCI-AACR annual meeting recently held in Geneva, Switzerland.

3 Nov 2008

Genentech submits application to FDA for Avastin in the most aggressive form of brain cancer

Genentech has announced that the company submitted a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for Avastin (bevacizumab) as a therapy for people with previously treated glioblastoma. If accepted by the FDA, the application would be considered for an accelerated approval that allows provisional approval of medicines for cancer or other life-threatening diseases based on preliminary evidence suggesting clinical benefit.

3 Nov 2008

Minor shift in vaccine schedule has potential to reduce infant illness, death

A new study by researchers at Wake Forest University School of Medicine and Vanderbilt University suggests that protecting infants from a common, highly contagious and even deadly disease may be as easy as administering a routine vaccine two weeks earlier than it is typically given.

3 Nov 2008

Magnet restores colour perception in partially-sighted patient

A researcher from the University of Essex has succeeded in inducing the experience of colour in the blind part of a partially sighted patient's visual field.

3 Nov 2008

First gene for child brain tumour identified

Scientists have found the first genetic link to a common childhood brain tumour - reveals research published in Cancer Research.

3 Nov 2008

Without glial cells, animals lose their senses

Sensory neurons have always put on a good show. But now it turns out they'll be sharing the credit. In groundbreaking research to appear in the October 31 issue of Science, Rockefeller University scientists show that while neurons play the lead role in detecting sensory information, a second type of cell, the glial cell, pulls the strings behind the scenes.

3 Nov 2008

Lithium carbonate to be tested for motor neurone disease

Victims of motor neurone disease (MND) will find hope from British research which has found that lithium carbonate, a cheap off-patent drug, may offer a treatment for the disease.

3 Nov 2008

Insomnia linked to a neurochemical abnormality in the brain

Scientists at the American Academy of Sleep Medicine have linked insomnia to a neurochemical abnormality in the brain.

3 Nov 2008

New method provides panoramic view of protein-RNA interactions in living cells

DNA, it has turned out, isn't all it was cracked up to be. In recent years we learned that the molecule of life, the discovery of the 20th century, did not - could not - by itself explain the huge differences in complexity between a human and a worm.

2 Nov 2008

Double-barreled immune cell approach for neuroblastoma

Adding an artificial tumor-specific receptor to immune system cells called T-lymphocytes that target a particular virus extended and improved the cells' ability to fight a form of childhood cancer called neuroblastoma, said researchers form Baylor College of Medicine and Texas Children's Hospital in a report that appears online in the journal Nature Medicine.

2 Nov 2008

Scientists develop genome-wide platform to study how specialized proteins regulate RNA in living, intact cells

DNA, it has turned out, isn't all it was cracked up to be. In recent years we learned that the molecule of life, the discovery of the 20th century, did not -- could not -- by itself explain the huge differences in complexity between a human and a worm.

2 Nov 2008

Alternative splicing in genes more prevalent than previously believed

Scientists have long known that it's possible for one gene to produce slightly different forms of the same protein by skipping or including certain sequences from the messenger RNA.

2 Nov 2008

Antioxidants reduce the toxic effects of lead

A research study carried out by the Universidad Complutense de Madrid (UCM) proves that administering natural antioxidants can reduce the effects of lead poisoning in animals during the gestation and lactation periods. The study suggests that it could also be effective in humans.

31 Oct 2008

Earlier jaundice treatment decreases brain injury in preterm infants

A study from a National Institutes of Health research network found that an early treatment to prevent severe newborn jaundice in extremely early preterm infants reduced the infants' rate of brain injury, a serious complication of severe jaundice.

30 Oct 2008

Three effective treatments for childhood anxiety disorders found

Treatment that combines a certain type of psychotherapy with an antidepressant medication is most likely to help children with anxiety disorders, but each of the treatments alone are also effective, according to a new study funded by the National Institute's of Health's National Institute of Mental Health (NIMH) The study was published online Oct. 30, in the New England Journal of Medicine.

30 Oct 2008

Pulsed ultrasound used to remote control brain circuits

In a twist on nontraditional uses of ultrasound, a group of neuroscientists at Arizona State University has developed pulsed ultrasound techniques that can remotely stimulate brain circuit activity.

29 Oct 2008

Professor reveals the 'Jennifer Aniston neuron'

According to a top scientist parts of the brain are wired up to be devoted to celebrities.

29 Oct 2008

Researchers discover how Sonic hedgehog gene controls brain development

University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics.

28 Oct 2008

High-fat diet could promote the development of Alzheimer's

A team of Université Laval researchers has shown that the main neurological markers for Alzheimer's disease are exacerbated in the brains of mice fed a diet rich in animal fat and poor in omega-3s. Details of the study-which suggests that diets typical of most industrialized countries promote the development of Alzheimer's-are outlined in the latest online edition of Neurobiology of Aging.

28 Oct 2008