Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Fruit flies illuminate the role of Alzheimer's disease risk genes

Scientists have identified hundreds of genes that may increase the risk of developing Alzheimer's disease but the roles these genes play in the brain are poorly understood.

29 Oct 2025

UCSF receives historic $100 million gift for Memory and Aging Center

UC San Francisco today announced a $100 million gift to its renowned Memory and Aging Center (MAC). It is the first gift to name a UCSF division, which will now be the Edward and Pearl Fein Memory and Aging Center.

29 Oct 2025

Exploring the gut-brain-immune axis in neurodegeneration

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.

28 Oct 2025

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer's disease therapy.

27 Oct 2025

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

23 Oct 2025

Revolutionizing gait analysis with wearable sensors and 3D depth cameras

A study from the College of Engineering and Computer Science and the Sensing Institute (I-SENSE) at Florida Atlantic University reveals that foot-mounted wearable sensors and a 3D depth camera can accurately measure how people walk – even in busy clinical environments – offering a powerful and more accessible alternative to traditional gait assessment tools.

23 Oct 2025

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will gather leading ALS researchers and clinicians to discuss the latest research and perspectives on the disease.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Earlier menopause and reduced cardiac function may negatively affect brain health

Women face a higher risk of developing both cardiovascular disease and Alzheimer's disease than men. Cardiovascular disease is linked to an increased likelihood of Alzheimer's disease, especially among women.

21 Oct 2025

Study offers a nuanced understanding of how bedroom ventilation affects sleep health

Good sleep is key to good health, overall well-being, and optimal cognitive function. Disturbed sleep or lack of sleep can lead to various health issues such as cardiovascular diseases, cancer, and other morbidity, including Alzheimer's disease and obesity.

21 Oct 2025

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Women are significantly more likely than men to develop Alzheimer's disease. Earlier age at menopause is associated with a greater risk for late-life cognitive decline and Alzheimer's disease.

21 Oct 2025

Transdermal hormone therapy offers potential reduction in anxiety and depression

Hormone therapy–oral and transdermal–remains the most effective treatment for such bothersome menopause symptoms as hot flashes and is generally considered safe for most patients. A new study shows that risk profiles are different based on how the hormones are administered.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

Social and environmental inequality linked to risk of Alzheimer’s

The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare.

20 Oct 2025

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

17 Oct 2025

New 3D human brain tissue platform integrates all major brain cell types into a single culture

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture.

17 Oct 2025

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule essential for the development and function of the nervous system, new research suggests.

17 Oct 2025

Advanced MRI technique reveals early markers of hereditary frontotemporal dementia

An international study led by researchers at Karolinska Institutet in Sweden demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques.

16 Oct 2025

Alzheimer's Disease News and Research

Further Reading

Fruit flies illuminate the role of Alzheimer's disease risk genes

UCSF receives historic $100 million gift for Memory and Aging Center

Exploring the gut-brain-immune axis in neurodegeneration

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Revolutionizing gait analysis with wearable sensors and 3D depth cameras

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

People with multiple sclerosis found to have dysbiotic oral microbiome

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Earlier menopause and reduced cardiac function may negatively affect brain health

Study offers a nuanced understanding of how bedroom ventilation affects sleep health

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Transdermal hormone therapy offers potential reduction in anxiety and depression

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Social and environmental inequality linked to risk of Alzheimer’s

Study reveals how a microglial mutation increases risk for Alzheimer's disease

New 3D human brain tissue platform integrates all major brain cell types into a single culture

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Advanced MRI technique reveals early markers of hereditary frontotemporal dementia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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